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Valneva (0OB3) (FR:VLA)
:VLA
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Valneva (VLA) AI Stock Analysis

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FR:VLA

Valneva

(LSE:VLA)

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Neutral 55 (OpenAI - 4o)
Rating:55Neutral
Price Target:
€5.00
▲(12.36% Upside)
Valneva's overall stock score is primarily influenced by its challenging financial performance and valuation concerns, despite strong technical indicators. The company's high leverage and negative cash flows are significant risks, while the bullish technical momentum offers some potential upside.

Valneva (VLA) vs. iShares MSCI France ETF (EWQ)

Valneva Business Overview & Revenue Model

Company DescriptionValneva SE, a specialty vaccine company, focuses on the development and commercialization of prophylactic vaccines for infectious diseases with unmet needs. Its commercial vaccines for travelers include IXIARO, an inactivated Vero cell culture-derived Japanese encephalitis vaccine indicated for active immunization against Japanese encephalitis; DUKORAL, an oral vaccine for the prevention of diarrhea caused by Vibrio cholera and/or heat-labile toxin producing Enterotoxigenic Escherichia coli bacterium; and VLA2001, a vaccine candidate against SARS-CoV-2. The company also develops VLA15, a vaccine candidate that has completed Phase II clinical trial against Borrelia; and VLA1553, a vaccine candidate, which is in Phase III clinical trial against the chikungunya virus. It sells its products in the United States, Canada, Germany, Austria, Nordics, the United Kingdom, other European countries, and internationally. Valneva SE has collaborations with Pfizer, Inc. to co-develop and commercialize its Lyme disease vaccine; and Instituto Butantan for the development, manufacturing, and marketing of single-shot chikungunya vaccine. The company was founded in 1998 and is headquartered in Saint-Herblain, France.
How the Company Makes MoneyValneva generates revenue primarily through the sale of its vaccine products, both commercialized and in development. The company also earns income through partnerships and collaborations with other pharmaceutical companies and government entities, which may include upfront payments, milestone payments, and royalties based on sales. Significant partnerships, such as those with the European Union for its COVID-19 vaccine and collaborations with major pharmaceutical firms, contribute to Valneva's earnings by providing funding for research and development, as well as access to larger distribution networks.

Valneva Earnings Call Summary

Earnings Call Date:Aug 12, 2025
(Q2-2025)
|
% Change Since: |
Next Earnings Date:Nov 13, 2025
Earnings Call Sentiment Neutral
Valneva's earnings call highlighted significant revenue growth, strong cash position, and positive progress in vaccine development. However, the company also faced challenges including operating losses and safety concerns for IXCHIQ. The highlights and lowlights were relatively balanced.
Q2-2025 Updates
Positive Updates
Significant Revenue Growth
Valneva achieved total revenues close to EUR 100 million, marking a very significant year-over-year growth. Product sales increased by 33.3% to EUR 91 million compared to EUR 68.3 million in the first half of 2024.
Strong Cash Position
The company reported a cash position of more than EUR 160 million, indicating a strong additional cash influx through ATM transactions and a significant reduction in operating cash burn.
Regulatory and Commercial Achievements
Valneva secured additional marketing authorizations for IXCHIQ in the UK, Brazil, and Europe, and announced an exclusive vaccine marketing and distribution agreement for Germany with CSL Seqirus.
Positive Progress in Vaccine Development
Valneva completed the vaccination in the current VALOR Phase III study for Lyme disease, observed a high sustained 1-year immune response in adolescents for IXCHIQ, and achieved positive Phase III pediatric safety and immunogenicity results for IXCHIQ.
Improved Gross Margin
The gross margin on commercial products, excluding IXCHIQ, increased to 59.2% in the first half of 2025 compared to 47.7% in the prior year.
Negative Updates
Operating Loss
Valneva reported an operating loss of EUR 16.8 million compared to an operating profit of EUR 46.7 million last year, which was due to the sale of a priority review voucher.
Decreased EBITDA
Adjusted EBITDA in the first half of 2025 was minus EUR 6 million compared to a positive EBITDA of EUR 56.2 million last year, excluding the one-off PRV sale.
Safety Concerns for IXCHIQ
The safety assessment by FDA and EMA showed safety signals during the vaccination campaign in La Réunion, leading to temporary age-related restrictions.
Company Guidance
During the recent call, Valneva provided guidance for 2025, projecting product sales between EUR 170 million and EUR 180 million, with total revenues expected to reach EUR 180 million to EUR 190 million. The company highlighted significant year-over-year growth, noting total revenues nearing EUR 100 million in the first half of 2025, along with a robust cash position of over EUR 160 million. Valneva emphasized its focus on strategic R&D investments, with expected R&D expenses between EUR 90 million and EUR 100 million, partially offset by grants and anticipated tax credits. The company also aims for a reduced operational cash usage by more than 50% year-over-year. Valneva remains optimistic about the future, expecting sustainable profitability following the successful approval and commercialization of its Lyme disease vaccine.

Valneva Financial Statement Overview

Summary
Valneva's financial performance is challenged by negative profitability and cash flow issues, despite some revenue growth. High leverage and negative returns on equity further emphasize the need for strategic improvements.
Income Statement
45
Neutral
Valneva's income statement shows a mixed performance. The TTM (Trailing-Twelve-Months) revenue growth rate of 5.52% indicates a positive trajectory compared to the previous year. However, the company struggles with profitability, as evidenced by negative net profit margins and EBIT margins. The gross profit margin has improved over time, but the consistent net losses highlight ongoing challenges in achieving profitability.
Balance Sheet
40
Negative
The balance sheet reveals a high debt-to-equity ratio of 1.20 in the TTM, indicating significant leverage. This could pose a risk if not managed properly. Return on equity remains negative, reflecting the company's struggle to generate returns for shareholders. The equity ratio suggests a moderate level of equity financing, but the high leverage remains a concern.
Cash Flow
35
Negative
Valneva's cash flow statement highlights challenges in cash generation, with negative operating and free cash flows in the TTM. The free cash flow growth rate is negative, indicating a decline in cash generation capabilities. The operating cash flow to net income ratio is also negative, underscoring the difficulty in converting earnings into cash flow.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue196.33M169.58M153.71M361.30M348.08M110.32M
Gross Profit96.25M71.04M52.84M36.86M160.16M56.02M
EBITDA-41.28M32.08M-57.72M-99.39M-46.87M-46.11M
Net Income-67.04M-12.25M-101.43M-143.28M-73.42M-64.39M
Balance Sheet
Total Assets472.63M500.03M460.06M621.34M817.35M449.16M
Cash, Cash Equivalents and Short-Term Investments161.31M168.27M126.08M289.43M346.64M204.39M
Total Debt196.92M216.31M208.82M152.38M114.66M105.45M
Total Liabilities286.19M318.78M331.81M401.55M646.77M371.74M
Stockholders Equity186.43M181.25M128.25M219.80M170.58M77.42M
Cash Flow
Free Cash Flow-34.39M-83.66M-217.06M-274.67M-16.27M118.27M
Operating Cash Flow-11.90M-67.22M-202.74M-245.34M76.90M137.74M
Investing Cash Flow-12.33M76.92M-20.59M-29.05M-93.12M-19.34M
Financing Cash Flow56.57M30.68M63.08M215.12M154.50M21.74M

Valneva Technical Analysis

Technical Analysis Sentiment
Positive
Last Price4.45
Price Trends
50DMA
4.30
Positive
100DMA
3.52
Positive
200DMA
3.25
Positive
Market Momentum
MACD
0.11
Positive
RSI
50.30
Neutral
STOCH
12.78
Positive
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For FR:VLA, the sentiment is Positive. The current price of 4.45 is below the 20-day moving average (MA) of 4.60, above the 50-day MA of 4.30, and above the 200-day MA of 3.25, indicating a neutral trend. The MACD of 0.11 indicates Positive momentum. The RSI at 50.30 is Neutral, neither overbought nor oversold. The STOCH value of 12.78 is Positive, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for FR:VLA.

Valneva Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
60
Neutral
$181.83M104.57-51.06%-45.41%-273.69%
58
Neutral
€6.31B-148.98%18.52%
55
Neutral
€764.66M-38.01%30.21%-76.83%
52
Neutral
€1.11B181.43%28.76%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
50
Neutral
€455.90M-152.03%-20.97%
39
Underperform
€496.15M-12.84%-81.94%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
FR:VLA
Valneva
4.45
1.79
67.29%
FR:GNFT
Genfit
3.64
-1.69
-31.63%
FR:ABVX
Abivax SA
81.10
71.47
742.16%
FR:DBV
DBV Technologies
3.08
2.37
335.55%
FR:IVA
Inventiva
3.57
1.07
42.80%
FR:MEDCL
MedinCell SA
33.68
18.04
115.35%
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Oct 01, 2025