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Valneva SE (FR:VLA)
:VLA

Valneva (VLA) AI Stock Analysis

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FR:VLA

Valneva

(VLA)

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Neutral 46 (OpenAI - 4o)
Rating:46Neutral
Price Target:
€4.00
▲(12.36% Upside)
Valneva's overall stock score is primarily impacted by its financial challenges, including negative profitability and cash flow issues. While there is some positive momentum from revenue growth and strategic partnerships, these are offset by significant operational and regulatory hurdles.
Positive Factors
Revenue Growth
Consistent revenue growth indicates a positive trajectory, suggesting effective market penetration and product demand, which can support long-term financial stability.
Strategic Partnerships
Strategic partnerships enhance market reach and distribution capabilities, potentially leading to increased sales and market share over time.
Product and Regulatory Achievements
Obtaining new marketing authorizations expands the company's market presence and regulatory compliance, supporting long-term growth and competitive positioning.
Negative Factors
Operating Loss
Sustained operating losses can hinder financial health, limiting the company's ability to reinvest in growth initiatives and affecting long-term profitability.
High Leverage
High leverage increases financial risk, potentially impacting the company's ability to finance operations and growth, and could lead to financial distress if not managed.
Uncertain Future for Zika Vaccine
Regulatory uncertainty for key pipeline products can delay market entry and revenue generation, impacting long-term growth prospects and investor confidence.

Valneva (VLA) vs. iShares MSCI France ETF (EWQ)

Valneva Business Overview & Revenue Model

Company DescriptionValneva SE, a specialty vaccine company, focuses on the development and commercialization of prophylactic vaccines for infectious diseases with unmet needs. Its commercial vaccines for travelers include IXIARO, an inactivated Vero cell culture-derived Japanese encephalitis vaccine indicated for active immunization against Japanese encephalitis; DUKORAL, an oral vaccine for the prevention of diarrhea caused by Vibrio cholera and/or heat-labile toxin producing Enterotoxigenic Escherichia coli bacterium; and VLA2001, a vaccine candidate against SARS-CoV-2. The company also develops VLA15, a vaccine candidate that has completed Phase II clinical trial against Borrelia; and VLA1553, a vaccine candidate, which is in Phase III clinical trial against the chikungunya virus. It sells its products in the United States, Canada, Germany, Austria, Nordics, the United Kingdom, other European countries, and internationally. Valneva SE has collaborations with Pfizer, Inc. to co-develop and commercialize its Lyme disease vaccine; and Instituto Butantan for the development, manufacturing, and marketing of single-shot chikungunya vaccine. The company was founded in 1998 and is headquartered in Saint-Herblain, France.
How the Company Makes MoneyValneva generates revenue through multiple streams, primarily from the sale of its vaccines. This includes direct sales to healthcare providers and governments, which are often secured through public health contracts and partnerships. Significant revenue has been driven by its contracts with governmental organizations for vaccine supply, such as those for its COVID-19 vaccine candidate, which included advanced purchase agreements. Additionally, the company may earn revenue through milestone payments and royalties from partnerships with larger pharmaceutical firms for co-development or licensing deals. The company’s ongoing R&D efforts and pipeline of vaccine candidates are expected to contribute to future revenue growth as they progress through clinical trials and regulatory approvals.

Valneva Earnings Call Summary

Earnings Call Date:Nov 20, 2025
(Q3-2025)
|
% Change Since: |
Next Earnings Date:Mar 19, 2026
Earnings Call Sentiment Neutral
Valneva reported overall revenue growth and made significant strides in regulatory achievements and strategic partnerships. However, the company faced challenges with an operating loss, the suspension of IXCHIQ in the U.S., and decreased sales for some products. The uncertainty around the Zika vaccine candidate also adds to future concerns.
Q3-2025 Updates
Positive Updates
Revenue Growth and Financial Management
Total revenues reached EUR 127 million at the 9-month time point, a substantial growth of almost 9%. Operating cash burn significantly reduced, resulting in a cash position of more than EUR 140 million. Successfully completed debt refinancing, enhancing financial flexibility.
Product and Regulatory Achievements
Secured additional marketing authorizations for IXCHIQ in the U.K. and Brazil. Completed vaccinations in the VALOR Phase III Lyme disease study. Reported positive data for chikungunya vaccine IXCHIQ and the second-generation Zika vaccine candidate, VLA1601.
Strategic Partnerships and Agreements
Announced an exclusive vaccine marketing and distribution agreement for Germany with CSL Seqirus. Found a new partner, Pharmakon, for financial support.
IXIARO Sales Growth
IXIARO sales reached EUR 74.3 million, increasing 12.5% over the prior year, driven by sales to the U.S. Department of Defense and increased sales in some European countries.
Negative Updates
Operating Loss and EBITDA
Valneva reported an operating loss of EUR 53.9 million compared to an operating profit of EUR 34.2 million in the prior year. Adjusted EBITDA reached a negative EUR 37.7 million compared to a positive EUR 48.6 million due to the previous sale of a Priority Review Voucher.
IXCHIQ Sales and FDA Suspension
IXCHIQ's sales reached EUR 7.6 million, but were significantly adversely impacted by the temporary restriction and U.S. license suspension. Awaiting further information from the FDA with no defined timeline for resolution.
DUKORAL Sales Decline
DUKORAL sales decreased from EUR 22.3 million to EUR 21.5 million, affected by foreign currency fluctuation and a distributor shift in Germany.
Uncertain Future for Zika Vaccine Candidate
The development of the Zika vaccine candidate is uncertain due to unclear regulatory pathways and lack of funding opportunities.
Company Guidance
During the Valneva 9 Months 2025 Financial Results Conference Call, several key metrics were highlighted. Total revenues reached EUR 127 million, marking a 9% growth compared to the previous year, despite geopolitical and IXCHIQ challenges. Product sales were EUR 119.4 million, with IXIARO contributing EUR 74.3 million, an increase of 12.5% year-over-year, driven by sales to the U.S. Department of Defense and European markets. DUKORAL sales slightly decreased to EUR 21.5 million. The cash position was over EUR 140 million, partly due to EUR 26 million from ATM transactions. Operating loss stood at EUR 53.9 million, with an adjusted EBITDA of negative EUR 37.7 million. Valneva confirmed its 2025 guidance of EUR 155-170 million in product sales and EUR 165-180 million in total revenues.

Valneva Financial Statement Overview

Summary
Valneva's financial performance is challenged by negative profitability and cash flow issues, despite some revenue growth. High leverage and negative returns on equity further emphasize the need for strategic improvements.
Income Statement
45
Neutral
Valneva's income statement shows a mixed performance. The TTM (Trailing-Twelve-Months) revenue growth rate of 5.52% indicates a positive trajectory compared to the previous year. However, the company struggles with profitability, as evidenced by negative net profit margins and EBIT margins. The gross profit margin has improved over time, but the consistent net losses highlight ongoing challenges in achieving profitability.
Balance Sheet
40
Negative
The balance sheet reveals a high debt-to-equity ratio of 1.20 in the TTM, indicating significant leverage. This could pose a risk if not managed properly. Return on equity remains negative, reflecting the company's struggle to generate returns for shareholders. The equity ratio suggests a moderate level of equity financing, but the high leverage remains a concern.
Cash Flow
35
Negative
Valneva's cash flow statement highlights challenges in cash generation, with negative operating and free cash flows in the TTM. The free cash flow growth rate is negative, indicating a decline in cash generation capabilities. The operating cash flow to net income ratio is also negative, underscoring the difficulty in converting earnings into cash flow.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue196.33M169.58M153.71M361.30M348.08M110.32M
Gross Profit96.25M71.04M52.84M36.86M160.16M56.02M
EBITDA-41.28M32.08M-57.72M-104.72M-38.73M-44.76M
Net Income-67.04M-12.25M-101.43M-143.28M-73.42M-64.39M
Balance Sheet
Total Assets472.63M500.03M460.06M621.34M817.35M449.16M
Cash, Cash Equivalents and Short-Term Investments161.31M168.27M126.08M289.43M346.64M204.39M
Total Debt196.92M216.31M208.82M152.38M114.66M105.45M
Total Liabilities286.19M318.78M331.81M401.55M646.77M371.74M
Stockholders Equity186.43M181.25M128.25M219.80M170.58M77.42M
Cash Flow
Free Cash Flow-34.39M-83.66M-217.06M-274.67M-16.27M118.27M
Operating Cash Flow-11.90M-67.22M-202.74M-245.34M76.90M137.74M
Investing Cash Flow-12.33M76.92M-20.59M-29.05M-93.12M-19.34M
Financing Cash Flow56.57M30.68M63.08M215.12M154.50M21.74M

Valneva Technical Analysis

Technical Analysis Sentiment
Negative
Last Price3.56
Price Trends
50DMA
3.92
Negative
100DMA
4.07
Negative
200DMA
3.47
Positive
Market Momentum
MACD
-0.10
Positive
RSI
39.44
Neutral
STOCH
8.48
Positive
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For FR:VLA, the sentiment is Negative. The current price of 3.56 is below the 20-day moving average (MA) of 3.79, below the 50-day MA of 3.92, and above the 200-day MA of 3.47, indicating a neutral trend. The MACD of -0.10 indicates Positive momentum. The RSI at 39.44 is Neutral, neither overbought nor oversold. The STOCH value of 8.48 is Positive, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for FR:VLA.

Valneva Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
60
Neutral
€248.13M-6.38-51.06%-45.41%-273.69%
53
Neutral
€7.79B-35.7718.52%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
50
Neutral
€722.49M-3.80-241.12%3.09%
47
Neutral
€697.12M-0.97-12.84%-81.94%
46
Neutral
€613.33M-5.80-55.53%13.48%-1299.09%
46
Neutral
€839.54M-41.44166.31%43.80%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
FR:VLA
Valneva
3.56
1.65
86.21%
FR:GNFT
Genfit
4.97
1.50
43.23%
FR:ABVX
Abivax SA
100.00
92.92
1312.43%
FR:DBV
DBV Technologies
3.60
2.97
474.16%
FR:IVA
Inventiva
3.65
1.40
62.22%
FR:MEDCL
MedinCell SA
25.18
8.42
50.24%

Valneva Corporate Events

Valneva’s Earnings Call: Growth Amid Challenges
Sep 1, 2025

Valneva’s recent earnings call painted a picture of both optimism and caution. The company celebrated significant revenue growth and a robust cash position, while also acknowledging challenges such as operating losses and safety concerns related to its IXCHIQ vaccine. The overall sentiment was balanced, with a mix of positive achievements and areas needing attention.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Dec 03, 2025