Successful Commercial Launch of Emrosi
Emrosi achieved $14.7 million in net sales during the 3 quarters it was commercially available in 2025; ~53,000 total prescriptions since promotion began in April 2025; Q4 prescription volume grew nearly 50% sequentially vs Q3; Q4 run-rate annualizes to over 126,000 prescriptions; unique prescribers grew from ~3,200 at year-end 2025 to over 3,500 currently (≈+9.4%).
Revenue Growth
Total revenues were $61.9 million for 2025, up 10% versus $56.1 million in 2024, driven primarily by Emrosi launch uptake.
Improved Margins
Gross margin expanded to 66.2% in 2025 from 62.8% in 2024, an improvement of ~3.4 percentage points, reflecting a more favorable product mix (Emrosi and QBREXZA) and lower inventory period costs.
Progress Toward Profitability
Adjusted EBITDA turned positive at $2.9 million in 2025 (from $0.8 million in 2024), an absolute improvement of $2.1 million; EBITDA improved by $5.2 million, narrowing the loss from $9.2 million in 2024 to a $4.0 million loss in 2025; company reported positive EBITDA and positive adjusted EBITDA in Q4 2025.
Stronger Balance Sheet and Working Capital
Cash at year-end was $24.1 million versus $20.3 million at 12/31/2024 (increase of $3.8 million, ≈+18.7%); working capital improved to $29.4 million from $13.0 million (increase of $16.4 million).
Clinical and Third-Party Validation
Emrosi's Phase III superiority data vs Oracea were published in JAMA Dermatology; the National Rosacea Society updated treatment algorithms recognizing Emrosi; management expects 2–3 additional publications in 2026—these third-party validations support payer and prescriber adoption.
Market Access Momentum
Approximately 100 million commercial covered lives currently have access to Emrosi via contracting with 2 of the top 3 GPOs; management expects the third major GPO imminently, expanding framework access toward ~150 million lives and supporting improved reimbursement and reduced reliance on co-pay assistance.
Improving Patient Retention Metrics
Refill behavior strengthened: refill ratio increased from ~1.0 refills per new prescription (Q3) to ~1.4 refills per new prescription (Q4), indicating improving patient satisfaction and potential for higher lifetime value per patient.
Planned Portfolio Expansion
Company plans to launch 1–2 incremental niche dermatology products in 2026 leveraging the existing dermatology commercial infrastructure, potentially augmenting base business revenue.