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Cadrenal Therapeutics, Inc. (CVKD)
NASDAQ:CVKD
US Market
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Cadrenal Therapeutics, Inc. (CVKD) AI Stock Analysis

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CVKD

Cadrenal Therapeutics, Inc.

(NASDAQ:CVKD)

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Neutral 43 (OpenAI - 5.2)
Rating:43Neutral
Price Target:
$2.00
▼(-1.96% Downside)
Action:Reiterated
Date:07/21/26
The score is primarily held down by weak financial performance (no revenue, widening losses, and heavy cash burn with a shrinking equity base) and bearish technicals (price below all key moving averages with negative momentum). Corporate events provide some offset via financing runway extension and Phase 3 planning progress, but leadership turnover and limited valuation support keep the overall score low.
Positive Factors
Low Leverage / Balance Sheet Flexibility
Zero reported debt across 2024–2025 and TTM reduces fixed obligations and interest exposure, giving management flexibility to allocate scarce capital toward clinical development and partnering. This durable balance sheet characteristic supports runway management and negotiation leverage over coming quarters.
Negative Factors
Sustained Cash Burn / Pre‑revenue Status
The company remains pre‑revenue while burning roughly $11M TTM in operating and free cash flow and reporting widening net losses. Persistent negative cash generation creates a structural dependence on external financing, increasing dilution risk and constraining the firm’s ability to self‑fund multi‑phase clinical programs.
Read all positive and negative factors
Positive Factors
Negative Factors
Low Leverage / Balance Sheet Flexibility
Zero reported debt across 2024–2025 and TTM reduces fixed obligations and interest exposure, giving management flexibility to allocate scarce capital toward clinical development and partnering. This durable balance sheet characteristic supports runway management and negotiation leverage over coming quarters.
Read all positive factors

Cadrenal Therapeutics, Inc. (CVKD) vs. SPDR S&P 500 ETF (SPY)

Cadrenal Therapeutics, Inc. Business Overview & Revenue Model

Company Description
Cadrenal Therapeutics, Inc. operates as a biopharmaceutical enterprise primarily engaged in clinical development. The company's core focus is the advancement of Tecarfarin, a novel therapeutic agent that has received orphan drug designation. This ...
How the Company Makes Money
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Cadrenal Therapeutics, Inc. Financial Statement Overview

Summary
Financial profile is weak: the company is pre-revenue with widening losses (TTM net loss ~ $11.9M) and materially negative operating/free cash flow (~ -$11.0M TTM), implying ongoing reliance on external financing. The main offset is low leverage (no debt), but equity has fallen sharply (to ~ $1.8M TTM), increasing dilution/financing risk.
Income Statement
12
Very Negative
Balance Sheet
34
Negative
Cash Flow
10
Very Negative
BreakdownTTMMar 2026Dec 2024Dec 2023Dec 2022
Income Statement
Total Revenue0.000.000.000.000.00
Gross Profit-956.000.00-1.88K0.00-1.27K
EBITDA-11.56M-13.23M-10.65M-8.34M-6.61M
Net Income-8.22M-13.24M-10.65M-8.36M-6.71M
Balance Sheet
Total Assets5.59M4.33M10.12M8.52M778.17K
Cash, Cash Equivalents and Short-Term Investments2.39M4.01M10.02M8.40M32.59K
Total Debt0.000.000.0021.35K640.71K
Total Liabilities1.50M1.59M2.68M826.88K6.33M
Stockholders Equity4.09M2.74M7.44M7.69M-5.55M
Cash Flow
Free Cash Flow-10.16M-12.60M-7.36M-3.53M-1.20M
Operating Cash Flow-10.16M-12.60M-7.36M-3.53M-1.20M
Investing Cash Flow-412.00-5.10K-6.54K-3.25K-2.28K
Financing Cash Flow6.98M6.60M8.98M11.90M1.24M

Cadrenal Therapeutics, Inc. Technical Analysis

Technical Analysis Sentiment
Negative
Last Price2.04
Price Trends
50DMA
2.79
Negative
100DMA
4.03
Negative
200DMA
6.35
Negative
Market Momentum
MACD
-0.27
Negative
RSI
31.71
Neutral
STOCH
21.74
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For CVKD, the sentiment is Negative. The current price of 2.04 is above the 20-day moving average (MA) of 2.00, below the 50-day MA of 2.79, and below the 200-day MA of 6.35, indicating a bearish trend. The MACD of -0.27 indicates Negative momentum. The RSI at 31.71 is Neutral, neither overbought nor oversold. The STOCH value of 21.74 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for CVKD.

Cadrenal Therapeutics, Inc. Risk Analysis

Cadrenal Therapeutics, Inc. disclosed 80 risk factors in its most recent earnings report. Cadrenal Therapeutics, Inc. reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Cadrenal Therapeutics, Inc. Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
46
Neutral
$15.58M-0.07-302.13%-97.99%99.28%
44
Neutral
$21.57M-1.74763.44%
43
Neutral
$6.56M-0.38-333.32%39.14%
40
Underperform
$6.04M-0.31-160.28%-84.26%14.73%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
CVKD
Cadrenal Therapeutics, Inc.
1.86
-10.82
-85.33%
DARE
Daré Bioscience
1.37
-0.83
-37.73%
HIND
Vyome Holdings
2.16
-11.84
-84.57%
CLGN
Collplant Holdings
0.32
-2.23
-87.52%
LNAI
Lunai Bioworks
2.24
-16.89
-88.29%
TAOX
Tao Synergies
3.48
-4.92
-58.57%

Cadrenal Therapeutics, Inc. Corporate Events

Business Operations and StrategyProduct-Related Announcements
Cadrenal Therapeutics Launches Cardiac Acute Care Franchise Strategy
Positive
Jul 21, 2026
Cadrenal Therapeutics, Inc., a late-stage biopharmaceutical player in critical care cardiology and orphan cardiovascular diseases, has built a portfolio around CAD-1005 for heparin-induced thrombocytopenia, frunexian for cardiac surgery anticoagul...
Business Operations and StrategyExecutive/Board Changes
Cadrenal Therapeutics Announces Chief Medical Officer Transition
Negative
Jul 17, 2026
On July 14, 2026, Cadrenal Therapeutics entered into a confidential separation agreement with Chief Medical Officer James J. Ferguson III, following his July 7, 2026 resignation notice, effective July 31, 2026. Under the agreement, the company wil...
Business Operations and StrategyExecutive/Board Changes
Cadrenal Therapeutics Announces Chief Medical Officer Resignation
Negative
Jul 10, 2026
On July 7, 2026, Cadrenal Therapeutics disclosed that Chief Medical Officer James J. Ferguson III had submitted his resignation, with his departure effective July 31, 2026. The move prompted the company to begin a search for a new CMO while negoti...
Business Operations and StrategyPrivate Placements and Financing
Cadrenal Therapeutics Secures Private Placement to Extend Runway
Positive
Jul 1, 2026
On June 30, 2026, Cadrenal Therapeutics entered a definitive agreement with a single healthcare-focused institutional investor for a private placement of 960,000 shares of common stock or pre-funded warrants, together with series C-1 and C-2 warra...
Executive/Board Changes
Cadrenal Names Interim CFO, Realigns Board Structure
Neutral
Jun 29, 2026
On June 25, 2026, Cadrenal Therapeutics appointed veteran finance executive John P. Sharp as interim chief financial officer under a new statement of work with Lohman Associates, which will provide his services at a flat hourly rate capped at 24 ...
Business Operations and StrategyProduct-Related Announcements
Cadrenal Pursues Rare Pediatric Designation for Tecarfarin
Positive
Jun 18, 2026
On June 18, 2026, Cadrenal Therapeutics announced plans to seek Rare Pediatric Disease Designation from the U.S. Food and Drug Administration for tecarfarin as a chronic oral anticoagulant in pediatric patients with Kawasaki disease who develop co...
Executive/Board Changes
Cadrenal Therapeutics Announces CFO Transition and Interim Appointment
Neutral
Jun 3, 2026
On May 28, 2026, Cadrenal Therapeutics, Inc. and Chief Financial Officer Matthew K. Szot mutually agreed to his transition out of the CFO role, with CEO Quang X. Pham immediately assuming the positions of interim Chief Financial Officer and interi...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Jul 21, 2026