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Cadrenal Therapeutics, Inc. (CVKD)
NASDAQ:CVKD
US Market

Cadrenal Therapeutics, Inc. (CVKD) AI Stock Analysis

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CVKD

Cadrenal Therapeutics, Inc.

(NASDAQ:CVKD)

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Neutral 46 (OpenAI - 5.2)
Rating:46Neutral
Price Target:
$7.00
▼(-45.82% Downside)
The score is held back primarily by weak financial performance (no revenue, widening losses, and accelerating cash burn alongside shrinking assets/equity), plus a clearly bearish technical setup with the price well below key moving averages. Positive corporate events provide some offset by strengthening the pipeline and governance, while valuation signals are limited by negative earnings and no dividend data.
Positive Factors
Pipeline Expansion
The acquisition of VLX-1005 strengthens Cadrenal's pipeline, potentially addressing significant market needs in anticoagulation, enhancing long-term growth prospects.
Regulatory Designations
These designations can expedite development and approval processes, providing a competitive advantage and potentially accelerating time-to-market for VLX-1005.
Leadership Strength
Dr. Golden's expertise in cardiovascular medicine and anticoagulation aligns with Cadrenal's mission, potentially enhancing strategic direction and clinical program success.
Negative Factors
Cash Burn
Persistent cash burn and negative cash flow indicate a need for external funding, which could lead to dilution or increased financial risk if not managed.
Widening Losses
Widening losses without revenue generation highlight financial instability, potentially impacting long-term viability and necessitating strategic financial management.
Asset Decline
Significant asset decline reduces financial flexibility and increases reliance on external funding, posing a risk to sustaining operations and strategic initiatives.

Cadrenal Therapeutics, Inc. (CVKD) vs. SPDR S&P 500 ETF (SPY)

Cadrenal Therapeutics, Inc. Business Overview & Revenue Model

Company DescriptionCadrenal Therapeutics, Inc. operates as a clinical development biopharmaceutical company. The company focuses on developing Tecarfarin, a novel therapy with orphan drug indication for the prevention of systemic thromboembolism of cardiac origin in patients with end-stage renal disease and atrial fibrillation. The company was incorporated in 2022 and is headquartered in Ponte Vedra, Florida.
How the Company Makes MoneyCadrenal Therapeutics makes money primarily through the development and commercialization of proprietary pharmaceuticals. Revenue is generated from the sale of these drugs once they receive regulatory approval and are brought to market. Additionally, the company may engage in strategic partnerships and collaborations with other pharmaceutical firms, which can provide additional revenue streams through licensing agreements, milestone payments, and royalties. These partnerships can also help Cadrenal Therapeutics expand its market reach and accelerate the development of its product pipeline.

Cadrenal Therapeutics, Inc. Financial Statement Overview

Summary
Cadrenal Therapeutics, Inc. exhibits financial challenges with no revenue generation and consistent losses over the past three years. The company relies heavily on financing to maintain operations, with no clear path to revenue or profit generation. While the absence of debt is a positive factor, the lack of operational cash flow and ongoing losses are key concerns for long-term sustainability.
Income Statement
Cadrenal Therapeutics, Inc. has reported zero revenue over the past three years, indicating no operational sales or income. The company consistently reports negative EBIT and net income, highlighting ongoing operational losses without any revenue growth trajectory.
Balance Sheet
The company's balance sheet shows improvement in equity from negative to positive values, mainly due to financing activities. However, there is a lack of revenue generation and reliance on external financing. The absence of debt is positive, but the company is not generating income to strengthen its financial position.
Cash Flow
Cadrenal Therapeutics, Inc. shows negative free cash flow, indicating cash outflows exceeding inflows from operations. Operating cash flows are negative and increasing in magnitude, primarily supported by financing cash inflows. There is no cash flow generated from operations, posing sustainability challenges.
BreakdownTTMDec 2024Dec 2023Dec 2022
Income Statement
Total Revenue0.000.000.000.00
Gross Profit-5.92K-1.88K0.00-1.27K
EBITDA-14.45M-10.65M-8.34M-6.61M
Net Income-14.39M-10.65M-8.36M-6.71M
Balance Sheet
Total Assets4.09M10.12M8.52M778.17K
Cash, Cash Equivalents and Short-Term Investments3.86M10.02M8.40M32.59K
Total Debt0.000.0021.35K640.71K
Total Liabilities1.35M2.68M826.88K6.33M
Stockholders Equity2.73M7.44M7.69M-5.55M
Cash Flow
Free Cash Flow-11.83M-7.36M-3.53M-1.20M
Operating Cash Flow-11.82M-7.36M-3.53M-1.20M
Investing Cash Flow-11.64K-6.54K-3.25K-2.28K
Financing Cash Flow11.33M8.98M11.90M1.24M

Cadrenal Therapeutics, Inc. Technical Analysis

Technical Analysis Sentiment
Negative
Last Price12.92
Price Trends
50DMA
10.00
Negative
100DMA
11.70
Negative
200DMA
12.83
Negative
Market Momentum
MACD
-0.82
Negative
RSI
45.65
Neutral
STOCH
64.55
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For CVKD, the sentiment is Negative. The current price of 12.92 is above the 20-day moving average (MA) of 8.14, above the 50-day MA of 10.00, and above the 200-day MA of 12.83, indicating a bearish trend. The MACD of -0.82 indicates Negative momentum. The RSI at 45.65 is Neutral, neither overbought nor oversold. The STOCH value of 64.55 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for CVKD.

Cadrenal Therapeutics, Inc. Risk Analysis

Cadrenal Therapeutics, Inc. disclosed 73 risk factors in its most recent earnings report. Cadrenal Therapeutics, Inc. reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Cadrenal Therapeutics, Inc. Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
50
Neutral
$28.29M-4.69
46
Neutral
$18.42M-0.98-468.03%-9.80%
44
Neutral
$19.36M-0.02-565.18%-48.74%89.18%
38
Underperform
$18.31M-1.41-92.74%280.77%32.82%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
CVKD
Cadrenal Therapeutics, Inc.
7.88
-8.11
-50.72%
DARE
Daré Bioscience
2.07
-1.26
-37.84%
HIND
Vyome Holdings
3.43
-496.57
-99.31%
CLGN
Collplant Holdings
1.44
-2.49
-63.36%
LNAI
Lunai Bioworks
0.91
-8.09
-89.89%
TAOX
Tao Synergies
5.34
2.00
59.88%

Cadrenal Therapeutics, Inc. Corporate Events

Private Placements and FinancingRegulatory Filings and Compliance
Cadrenal Therapeutics Expands At-The-Market Stock Offering Capacity
Neutral
Dec 23, 2025

On December 23, 2025, Cadrenal Therapeutics, Inc. filed a prospectus supplement with the U.S. Securities and Exchange Commission to continue using its at-the-market equity offering program, allowing the company to offer and sell up to an additional $1,770,028 of its common stock through H.C. Wainwright & Co. as sales agent. This supplemental capacity, which follows approximately $10.0 million of stock already sold under the existing March 11, 2024 agreement, provides Cadrenal with flexible, discretionary access to incremental capital, while specifying parameters such as trading periods, volume limits, and minimum prices, and compensating H.C. Wainwright with a 3% fee on gross sales, with no obligation for the company to sell any shares and the ability for either party to terminate the arrangement under agreed conditions.

The most recent analyst rating on (CVKD) stock is a Buy with a $45.00 price target. To see the full list of analyst forecasts on Cadrenal Therapeutics, Inc. stock, see the CVKD Stock Forecast page.

Business Operations and StrategyPrivate Placements and Financing
Cadrenal Therapeutics Announces New Securities Purchase Agreement
Neutral
Dec 16, 2025

On December 15, 2025, Cadrenal Therapeutics, Inc. entered into a securities purchase agreement for a registered direct offering of 207,374 shares of common stock and unregistered warrants to purchase up to 414,748 shares, aiming to raise approximately $2.2 million. The offering, expected to close on December 16, 2025, includes a lock-up period and restrictions on further stock issuance, impacting the company’s financial strategy and market operations.

The most recent analyst rating on (CVKD) stock is a Buy with a $45.00 price target. To see the full list of analyst forecasts on Cadrenal Therapeutics, Inc. stock, see the CVKD Stock Forecast page.

M&A Transactions
Cadrenal Therapeutics Acquires VLX-1005 from Veralox
Positive
Dec 11, 2025

On December 10, 2025, Cadrenal Therapeutics acquired VLX-1005 and related assets from Veralox Therapeutics, enhancing its pipeline with a first-in-class drug candidate targeting immune signaling pathways in HIT. This acquisition, announced on December 11, 2025, positions Cadrenal to address the $40 billion global anticoagulation market and the $1 billion HIT market in the US and EU. VLX-1005, which has received Orphan Drug and Fast Track designations from the FDA, has shown promising results in Phase 1 and Phase 2 studies, potentially improving patient outcomes. The acquisition agreement includes upfront and milestone payments to Veralox, along with royalties on future global sales, enabling Cadrenal to focus on advancing VLX-1005’s clinical development.

The most recent analyst rating on (CVKD) stock is a Buy with a $45.00 price target. To see the full list of analyst forecasts on Cadrenal Therapeutics, Inc. stock, see the CVKD Stock Forecast page.

Business Operations and StrategyExecutive/Board Changes
Cadrenal Therapeutics Appoints Dr. Golden to Board
Positive
Dec 1, 2025

On December 1, 2025, Cadrenal Therapeutics announced the appointment of Dr. Lee Scott Golden to its Board of Directors. Dr. Golden brings over 25 years of experience in clinical development, particularly in cardiovascular medicine and anticoagulation, aligning with the company’s mission to advance safer anticoagulant options. His expertise is expected to guide Cadrenal’s strategy and clinical programs, potentially enhancing its industry positioning and value for shareholders.

The most recent analyst rating on (CVKD) stock is a Buy with a $45.00 price target. To see the full list of analyst forecasts on Cadrenal Therapeutics, Inc. stock, see the CVKD Stock Forecast page.

Private Placements and FinancingRegulatory Filings and Compliance
Cadrenal Therapeutics Announces New Stock Offering Program
Neutral
Nov 18, 2025

On November 18, 2025, Cadrenal Therapeutics, Inc. announced the filing of a prospectus supplement with the SEC for an ‘at the market offering’ program, allowing the sale of up to $3,438,062 of its common stock through H.C. Wainwright & Co., LLC. This move follows the company’s previous sale of $9,386,964 in shares under the same agreement. The offering is conducted under a registration statement effective since March 2024, and the agreement allows for flexible sales parameters. The company retains the right to suspend or terminate the agreement, and Wainwright will receive a 3% commission on sales.

The most recent analyst rating on (CVKD) stock is a Buy with a $45.00 price target. To see the full list of analyst forecasts on Cadrenal Therapeutics, Inc. stock, see the CVKD Stock Forecast page.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Dec 30, 2025