Pivotal Phase II Trial Initiation
Cellectis is preparing to initiate a pivotal Phase II trial for lasme-cel, UCART22, in relapsed or refractory acute lymphoblastic leukemia in the second half of 2025, following successful end of Phase I discussions with the FDA and EMA.
Strategic Collaboration with AstraZeneca
Research and development activities are ongoing under the partnership with AstraZeneca, covering three cell and gene therapy programs targeting hematological malignancies, solid tumors, and a genetic disorder.
Financial Sufficiency
Cellectis reports a cash position of $230 million as of June 30, 2025, sufficient to fund operations into H2 2027, including pivotal studies for lasme-cel and eti-cel.
Expansion of Clinical Trial Sites
Cellectis is expanding clinical trial sites in the United States and Europe, including the UK, to accelerate recruitment for the Phase II study of UCART22.