Strong Revenue Growth
Continuing Lonza CDMO business delivered CHF 6.5 billion in sales for FY2025, an increase of CHF 1.0 billion versus FY2024 and +21.7% in constant currencies, ahead of upgraded guidance (20%–21%).
Margin Expansion and Profitability
CORE EBITDA margin expanded to 31.6%, up 1.4 percentage points versus prior year and above the guided range of 30%–31%; management expects further expansion to above 32% in 2026.
Vacaville Integration and Contribution
Vacaville acquisition (paid CHF 1.1 billion) contributed roughly CHF 0.6 billion in sales in 2025 (slightly above prior CHF 0.5 billion forecast), successful tech transfer, post-merger integration finalized mid-2025, and only minor FDA observations resolved rapidly.
Organic Growth in Underlying Business
Excluding Vacaville, the organic CDMO business grew at low-teens in line with Lonza's CDMO organic growth model; management cites underlying market/outlook supporting low-teens structural growth (10%–13%).
Contracting Momentum and Future Revenue Visibility
Commercial contracting well above CHF 10 billion signed in 2025 (adds to CHF10bn+ in prior years) providing multi-year revenue visibility; 23 large growth CapEx projects (~CHF 7 billion) underway, 90% aimed at commercial/mixed assets in U.S. and Europe.
Platform Outperformance – Advanced Synthesis (ADS)
ADS grew ~22% organically in 2025 with margin improvement of ~5 percentage points to ~42%, driven by bioconjugates and small molecule ramp-ups; management expects ADS margins to remain a strong contributor going forward.
Cash Generation and Working Capital Improvement
Continuing business free cash flow of CHF 545 million in 2025 (almost double 2024), driven by disciplined CapEx, strong inventory and trade working capital management (trade working capital fell as % of sales by ~5 points).
Shareholder Returns and ESG Milestones
Board proposed a 25% dividend increase to CHF 5.00 per share; ESG targets (GHG emission intensity and waste intensity) met five years ahead of schedule with electricity in U.S./Europe/China from renewable sources as of Jan 2026; EcoVadis Gold rating and Ethisphere recognition.