Clinical DevelopmentCERo's CER-1236 modified T cells employ the extracellular domain of TIM-4, potentially mitigating cytokine release syndrome and neurotoxicity seen in traditional CAR-T therapies.
Safety ProfileNo safety issues reported so far, with one patient in the first cohort cleared for dose intensification, indicating a positive safety profile.
Unique Therapeutic ApproachThe unique approach of using TIM-4 receptor in CER-1236 structure is seen as a key differentiator from other CAR-T therapies.