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Orthocell Ltd (AU:OCC)
ASX:OCC
Australian Market

Orthocell Ltd (OCC) AI Stock Analysis

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AU:OCC

Orthocell Ltd

(Sydney:OCC)

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Neutral 41 (OpenAI - 5.2)
Rating:41Neutral
Price Target:
AU$0.70
â–Ľ(-13.33% Downside)
Action:ReiteratedDate:11/19/25
Orthocell Ltd faces significant challenges with profitability and cash flow, as reflected in its financial performance score. Technical analysis indicates bearish momentum, and valuation metrics are unattractive due to negative earnings. These factors collectively result in a low overall stock score.
Positive Factors
Top-line growth
Sustained revenue growth of 19.57% indicates expanding commercial traction for Orthocell’s collagen and cell‑therapy products. Over the medium term this supports scale economies, stronger distributor and surgeon adoption, and a larger addressable market to drive durable sales expansion.
Conservative leverage
A very low debt-to-equity ratio (0.04) provides financial flexibility and lowers fixed interest obligations. Structurally this reduces solvency risk, helps preserve runway for R&D and commercialization, and improves capacity to fund growth through equity or internal cash rather than costly debt.
Improving free cash flow
A 12.12% improvement in free cash flow and an FCF/net income ratio >1 show progress converting operations into cash despite accounting losses. This durable improvement enhances funding flexibility for manufacturing scale-up and clinical programs without immediate reliance on dilutive capital.
Negative Factors
Sustained unprofitability
Persistent negative net and EBIT margins indicate the business has yet to translate revenue into sustainable profits. Over months this constrains reinvestment, weakens return metrics, and obliges management to secure external funding or materially improve margins to achieve self-sustaining growth.
Negative operating cash flow
Negative operating cash flow signals the core business is not yet cash-generative and requires ongoing financing to support operations and manufacturing scale. This structural cash gap increases refinancing risk and may limit the company’s ability to invest in commercialization or clinical development.
Severe EPS decline
A very large negative EPS growth rate (-232.68%) reflects severe earnings deterioration and raises concerns about margin sustainability and profitability trajectory. Over the medium term this undermines investor confidence and can restrict access to favourable capital and partnership terms.

Orthocell Ltd (OCC) vs. iShares MSCI Australia ETF (EWA)

Orthocell Ltd Business Overview & Revenue Model

Company DescriptionOrthocell Limited, a regenerative medicine company, develops and commercializes cell therapies and biological medical devices for the repair of various bone and soft tissue injuries in Australia. The company offers CelGro, a naturally derived collagen medical device for use in multiple indications to augment the surgical repair of bone, peripheral nerves, tendons, and cartilage; and Ortho-ATI, a cell therapy for treatment of chronic tendon injuries. It also provides Ortho-ACI, an autologous chondrocyte implantation to treat articular cartilage defects in the knee and ankle; Striate+, a resorbable collagen membrane used for guided bone and tissue regeneration in dental application; and Remplir, a collagen scaffold used in peripheral nerve repair. Orthocell Limited was incorporated in 2006 and is headquartered in Murdoch, Australia.
How the Company Makes MoneyOrthocell makes money primarily by selling its commercial regenerative medicine products and associated services into healthcare markets. Key revenue streams include: (1) Product sales of its collagen-based implant/device products used in surgical repair (e.g., for tendon/soft-tissue indications), sold through distributors and/or direct hospital and surgeon channels depending on market. Revenue is recognised from supplying these devices for clinical use. (2) Revenue from autologous cell therapy services where patient-derived cells are processed/manufactured under controlled conditions and supplied for clinical use; in these models, Orthocell generates income from manufacturing/processing fees and/or per-treatment supply. (3) Commercialisation-related income tied to market access and distribution arrangements, where applicable; if Orthocell has regional distributors, earnings can be influenced by distributor ordering patterns, pricing agreements, and market expansion milestones. (4) Other operating income may include research and development grants or similar non-dilutive funding where awarded; specific amounts and materiality are null. Significant factors that can affect earnings include regulatory approvals and reimbursement coverage in target markets, adoption by surgeons and hospitals, the company’s ability to scale manufacturing for biologics/cell therapies, and the effectiveness of distribution partnerships (specific partners and financial terms: null).

Orthocell Ltd Financial Statement Overview

Summary
Orthocell Ltd is experiencing revenue growth, but profitability remains a significant challenge with negative margins and returns. The balance sheet is stable with low leverage, but cash flow issues persist, impacting the company's ability to generate positive cash flow from operations.
Income Statement
45
Neutral
Orthocell Ltd has shown a positive revenue growth rate of 19.57% in the latest year, indicating a growing top line. However, the company is struggling with profitability, as evidenced by negative net profit margins and EBIT margins. The gross profit margin has decreased slightly from the previous year, suggesting some pressure on cost management.
Balance Sheet
50
Neutral
The company maintains a low debt-to-equity ratio of 0.04, indicating conservative leverage. However, the return on equity is negative, reflecting ongoing losses. The equity ratio is healthy, suggesting a strong capital structure, but the negative ROE highlights profitability challenges.
Cash Flow
40
Negative
Orthocell Ltd has improved its free cash flow growth rate by 12.12%, but the operating cash flow remains negative, indicating cash flow challenges. The free cash flow to net income ratio is above 1, suggesting that the company is generating cash flow relative to its net losses, but the overall cash flow position is weak.
BreakdownTTMJun 2025Jun 2024Jun 2023Jun 2022Jun 2021
Income Statement
Total Revenue9.41M7.55M5.32M4.24M1.53M1.02M
Gross Profit3.50M4.80M3.69M3.06M832.52K299.88K
EBITDA-15.31M-13.43M-11.68M-10.34M-11.52M-11.67M
Net Income-12.48M-8.57M-7.18M-6.25M-9.11M-9.04M
Balance Sheet
Total Assets59.80M35.24M26.62M29.61M37.90M19.33M
Cash, Cash Equivalents and Short-Term Investments44.37M28.62M20.61M24.82M11.02M16.33M
Total Debt835.79K576.89K689.69K562.30K507.56K621.72K
Total Liabilities18.64M20.67M22.08M23.46M27.99M2.46M
Stockholders Equity41.16M14.57M4.53M6.15M9.90M16.87M
Cash Flow
Free Cash Flow-12.21M-9.04M-7.45M13.96M-6.80M-4.82M
Operating Cash Flow-12.05M-8.68M-6.51M14.59M-6.26M-4.63M
Investing Cash Flow-42.26M-359.06K-942.02K-631.56K-535.02K-188.52K
Financing Cash Flow30.84M17.05M3.24M-164.61K1.49M709.15K

Orthocell Ltd Technical Analysis

Technical Analysis Sentiment
Negative
Last Price0.81
Price Trends
50DMA
0.91
Negative
100DMA
0.99
Negative
200DMA
1.12
Negative
Market Momentum
MACD
-0.05
Positive
RSI
24.87
Positive
STOCH
8.76
Positive
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For AU:OCC, the sentiment is Negative. The current price of 0.81 is below the 20-day moving average (MA) of 0.85, below the 50-day MA of 0.91, and below the 200-day MA of 1.12, indicating a bearish trend. The MACD of -0.05 indicates Positive momentum. The RSI at 24.87 is Positive, neither overbought nor oversold. The STOCH value of 8.76 is Positive, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for AU:OCC.

Orthocell Ltd Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
46
Neutral
AU$113.45M-1.51-265.55%―-20.79%73.98%
44
Neutral
AU$192.13M-5.17-83.97%―1271.12%36.87%
42
Neutral
AU$80.88M-14.80-40.65%―700.00%26.88%
41
Neutral
AU$195.34M-12.98-44.80%―42.05%-0.84%
41
Neutral
AU$138.81M-2.84279.21%――0.66%
40
Underperform
AU$70.74M-3.40-35.86%――-19.21%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
AU:OCC
Orthocell Ltd
0.72
-0.84
-53.85%
AU:PAR
Paradigm Biopharmaceuticals
0.26
-0.14
-34.62%
AU:IMM
Immutep Ltd
0.05
-0.24
-83.16%
AU:DXB
Dimerix Limited
0.32
-0.16
-33.33%
AU:RCE
Recce Pharmaceuticals Ltd.
0.48
0.12
34.83%
AU:ALA
Arovella Therapeutics Limited
0.07
-0.02
-22.99%

Orthocell Ltd Corporate Events

Orthocell reports lapse of 16,567 retention rights, trimming potential equity
Mar 16, 2026

Orthocell Ltd has notified the market that 16,567 retention rights, classified as OCCAAH securities, have lapsed after conditions attached to these rights were not met or became incapable of being satisfied. The cessation of these conditional securities, effective 31 December 2025, results in a small reduction of potential future equity issuance and slightly streamlines the company’s capital structure without impacting existing ordinary shareholders.

The announcement, lodged as a new Appendix 3H on 16 March 2026, reflects Orthocell’s ongoing obligations to keep investors informed of changes to its issued and potential capital. While the lapse of retention rights may signal that certain performance or service milestones were not achieved, it also limits dilution for current investors and underscores the contingent nature of incentive-based equity awards in ASX-listed companies.

The most recent analyst rating on (AU:OCC) stock is a Sell with a A$0.77 price target. To see the full list of analyst forecasts on Orthocell Ltd stock, see the AU:OCC Stock Forecast page.

Orthocell Issues New Retention and Performance Rights Under Employee Incentive Plan
Mar 16, 2026

Orthocell Ltd has issued 654,963 retention rights and 240,065 performance rights as unquoted securities under its employee incentive scheme, effective 16 March 2026. The new rights, which are subject to transfer restrictions and will not be quoted on the ASX, underscore the company’s use of equity-based incentives to retain and motivate staff, aligning employee interests with long-term shareholder value.

The move signals Orthocell’s continued reliance on structured equity remuneration to support its growth and development efforts in regenerative medicine. While the issuance does not immediately affect the company’s quoted share capital, it may contribute to future dilution and reflects ongoing investment in human capital as a strategic asset in a competitive biotech sector.

The most recent analyst rating on (AU:OCC) stock is a Sell with a A$0.77 price target. To see the full list of analyst forecasts on Orthocell Ltd stock, see the AU:OCC Stock Forecast page.

Orthocell Taps LEDA for UK Launch of Remplir Nerve Repair Device
Mar 9, 2026

Orthocell has appointed LEDA Orthopaedics as the exclusive distributor for its Remplir nerve repair device in the United Kingdom, a move that underpins its strategy to penetrate the UK and EU peripheral nerve repair market estimated at US$750 million annually. LEDA, a specialist orthopaedic distributor with more than 40 sales representatives and strong surgeon relationships, will begin pre-launch activities such as surgeon engagement, medical education and hospital procurement planning while Orthocell awaits anticipated UK/EU regulatory approval in Q3 FY26.

The UK rollout will be supported by Orthocell’s Australian-based commercial and medical education teams, leveraging programs and clinical evidence that have driven successful launches in Australia and the United States. With Remplir already approved and selling in multiple markets including Australia, New Zealand, Singapore, the US and Hong Kong, and first Canadian sales expected in the near term, Orthocell’s approximately $49 million in cash reserves provide a strong balance sheet to execute its global distribution strategy and accelerate commercial adoption in new territories.

The most recent analyst rating on (AU:OCC) stock is a Sell with a A$0.84 price target. To see the full list of analyst forecasts on Orthocell Ltd stock, see the AU:OCC Stock Forecast page.

Orthocell director Michael McNulty increases on‑market shareholding
Feb 25, 2026

Orthocell Limited has reported a change in the holdings of director Michael McNulty, who maintains both direct and indirect interests in the company’s securities through personal holdings, a family trust structure and his spouse. The disclosure forms part of the company’s ongoing compliance with ASX requirements to keep the market informed about changes in director interests.

McNulty acquired 26,041 ordinary shares on market on 25 February 2026 for a total consideration of $25,031.26, increasing his direct shareholding to 50,602 ordinary shares while retaining 2,000,000 unlisted options and his spouse’s 56,169 shares. The transaction, which did not occur during a closed period, may be interpreted by investors as a signal of confidence from the director and marginally increases insider ownership in Orthocell.

The most recent analyst rating on (AU:OCC) stock is a Sell with a A$0.86 price target. To see the full list of analyst forecasts on Orthocell Ltd stock, see the AU:OCC Stock Forecast page.

Orthocell Director Increases Shareholding Through On-Market Purchase
Feb 25, 2026

Orthocell has disclosed a change in director John Van Der Wielen’s interests following an on‑market purchase of 32,500 ordinary shares for $31,337. The transaction increases his direct equity exposure while leaving his 4,000,000 unlisted options, exercisable at $0.40 each by 29 May 2028, and his existing 541,666 ordinary shares unchanged, signalling continued alignment between board and shareholder interests.

The acquisition was executed outside a closed trading period and did not involve any related contracts or derivative arrangements. This incremental share purchase modestly strengthens insider ownership, which may be viewed positively by investors monitoring governance, director confidence and capital markets activity around Orthocell’s regenerative medicine portfolio.

The most recent analyst rating on (AU:OCC) stock is a Sell with a A$0.86 price target. To see the full list of analyst forecasts on Orthocell Ltd stock, see the AU:OCC Stock Forecast page.

Orthocell posts record half-year revenue as global expansion gains pace
Feb 23, 2026

Orthocell has reported record first-half FY26 revenue of $6.2 million, up 48% year-on-year, driven by rising adoption of its Striate+ and Remplir products and improved gross margins of 55%. The company remains loss-making, with a $5.2 million net loss after tax reflecting heavy investment in U.S. commercial infrastructure, automation and systems to support its global scale-up.

The U.S. launch of Remplir is advancing, with approvals secured in 45 states and growing hospital account penetration, while national distribution in Canada and new channels in Hong Kong bolster its international footprint. Orthocell is also targeting nerve-sparing prostate surgery and preparing EU and U.K. market entry, supported by a strong $49.4 million cash position and portfolio expansion via PearlBone, which together position the company for broader market access and long-term growth.

The most recent analyst rating on (AU:OCC) stock is a Buy with a A$1.33 price target. To see the full list of analyst forecasts on Orthocell Ltd stock, see the AU:OCC Stock Forecast page.

Orthocell Issues Confidential US Market Update with Standard Legal Disclaimers
Feb 1, 2026

Orthocell Ltd has issued a US market and operational update presentation, but the released text consists solely of standard legal and confidentiality disclaimers typically accompanying investor or corporate communications. The document outlines that the material is not an offer or solicitation for securities, must not be relied upon as comprehensive investment advice, is confidential and restricted in its use and distribution, and that any forward-looking statements are subject to significant risks and uncertainties, underscoring limited liability and no obligation to update such statements beyond legal requirements.

The most recent analyst rating on (AU:OCC) stock is a Buy with a A$1.33 price target. To see the full list of analyst forecasts on Orthocell Ltd stock, see the AU:OCC Stock Forecast page.

Orthocell to Brief Investors on US Rollout of Remplir and Operational Progress
Jan 29, 2026

Orthocell Limited will host an investor webinar on 2 February 2026 to provide an operational update, with a particular focus on the rollout of its Remplir nerve repair device in the United States. The briefing, led by the company’s chairman and chief executive, underscores the strategic importance of the US market to Orthocell’s growth, following recent regulatory clearances and the establishment of a specialist US distributor network that has already generated initial sales, and will give investors and stakeholders further insight into how its expanding product portfolio and regulatory progress are shaping its commercial trajectory in regenerative medicine.

The most recent analyst rating on (AU:OCC) stock is a Buy with a A$1.33 price target. To see the full list of analyst forecasts on Orthocell Ltd stock, see the AU:OCC Stock Forecast page.

Orthocell Posts Record Revenue as Remplir Global Rollout Accelerates
Jan 18, 2026

Orthocell reported its seventh consecutive quarter of record revenue, posting $3.2 million for the December 2025 quarter, up 45% year on year, driven by accelerating adoption of its Remplir nerve repair device and initial US sales. Backed by $49.4 million in cash following a heavily supported $30 million capital raising, the company is ramping up global commercialisation of Remplir with a distributor network now covering more than 25 US states, early traction in Canada and Hong Kong, and a regulatory application lodged for entry into the sizeable EU and UK nerve repair markets; it also secured global distribution rights to PearlBone bone regeneration technology and is building a new commercial opportunity in nerve-sparing prostate cancer surgery that could expand its US addressable market to about US$2 billion.

The most recent analyst rating on (AU:OCC) stock is a Buy with a A$1.33 price target. To see the full list of analyst forecasts on Orthocell Ltd stock, see the AU:OCC Stock Forecast page.

Orthocell Deepens Stake in Marine Biomedical and Secures Rights to PearlBone Bone Regeneration Technology
Jan 15, 2026

Orthocell has executed a binding agreement with Marine Biomedical Pty Ltd, lifting its equity stake from 1.72% to 11.7% for AU$1.05 million and securing a first right of refusal over global distribution rights for PearlBone, a next-generation bone substitute made from sustainably sourced pearl shells, as well as future bone repair products. The deal converts a prior memorandum into a formal strategic partnership, broadening Orthocell’s offering into bone regeneration alongside its existing nerve and tendon repair technologies and positioning it as a multi-tissue regenerative medicine provider targeting complex trauma and reconstructive procedures. With Marine Biomedical progressing PearlBone toward a U.S. FDA 510(k) submission and potential entry into the US$1.6 billion global bone substitute market, Orthocell aims to capitalise on its U.S. distribution network, supported by robust cash reserves of $49.4 million to fund ongoing commercial expansion.

The most recent analyst rating on (AU:OCC) stock is a Buy with a A$1.33 price target. To see the full list of analyst forecasts on Orthocell Ltd stock, see the AU:OCC Stock Forecast page.

Orthocell Delivers Seventh Straight Record Quarter as Remplir Expansion Gains Pace in North America
Jan 5, 2026

Orthocell reported record quarterly revenue of $3.2 million for the December 2025 quarter, its seventh consecutive quarter of record sales, driven by strong Remplir nerve repair product uptake in existing markets and initial U.S. sales. The company’s hybrid U.S. market entry strategy—combining specialist distributors with internal field leadership—is gaining traction, with distributor coverage now spanning more than 25 states, 23 hospital Value Analysis Committee approvals, and multiple medical education events completed, while Canadian market entry is underway. Supported by $49.4 million in cash reserves, no debt and an expected R&D tax refund, Orthocell is well positioned to accelerate Remplir adoption and pursue a step-change in revenue as it scales across North America.

The most recent analyst rating on (AU:OCC) stock is a Buy with a A$1.33 price target. To see the full list of analyst forecasts on Orthocell Ltd stock, see the AU:OCC Stock Forecast page.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Nov 19, 2025