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Noxopharm Ltd. (AU:NOX)
ASX:NOX
Australian Market

Noxopharm Ltd. (NOX) AI Stock Analysis

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AU:NOX

Noxopharm Ltd.

(Sydney:NOX)

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Neutral 43 (OpenAI - 5.2)
,
Neutral 43 (OpenAI - 5.2)
,
Neutral 43 (OpenAI - 5.2)
Rating:43Neutral
Price Target:
AU$0.06
▼(-34.44% Downside)
Action:ReiteratedDate:02/11/26
The score is primarily held down by weak financial performance (persistent losses, ongoing cash burn, and a 2025 deterioration in balance-sheet strength with higher leverage). Technicals also point to a weak trend with negative/soft momentum, while valuation support is limited because the company is loss-making (negative P/E) and no dividend yield is provided.
Positive Factors
Focused oncology R&D pipeline
Noxopharm's strategic focus on small-molecule oncology candidates targeted to boost radiotherapy and immuno-oncology effectiveness is a durable fundamental. A clear therapeutic niche and proprietary platforms support long-term clinical value creation if trials progress, underpinning sustained R&D optionality and partner interest over multiple years.
Partnering and commercialization pathway
An explicit strategy to engage external partners reduces capital intensity and leverages third-party development and commercialization capabilities. Over 2-6 months this structural approach can materially de-risk late-stage development, extend runway indirectly, and improve chances of market entry without needing sole internal commercialization investment.
Improving free cash flow trend
An improvement in free cash flow versus the prior year, even from a negative base, suggests operational adjustments or revenue mix gains beginning to take hold. If sustained, this durable trend can reduce future financing needs, lengthen runway, and indicate management capability to extract efficiencies while progressing clinical programs.
Negative Factors
Weakened balance sheet and high leverage
The material 2025 balance-sheet deterioration, with debt roughly 3.6x equity, materially reduces financial flexibility. High leverage increases refinancing and covenant risk, raises cost of capital, and constrains ability to fund lengthy clinical programs internally, making the company more dependent on dilutive or costly external funding.
Persistent heavy cash burn
Consistent negative operating and free cash flow across years is a structural weakness for a clinical-stage biotech. Ongoing burn requires repeated external financing, which can dilute shareholders and divert management focus. Sustained negative cash flow increases execution risk for multi-year clinical development plans.
Negative gross profit and large operating losses
A negative gross profit and materially larger operating losses in 2025 indicate the core business is not economically sustainable today. Such deep losses limit reinvestment capacity, heighten reliance on capital markets or partners, and elevate the risk that clinical programs may be slowed or reprioritized if funding becomes constrained.

Noxopharm Ltd. (NOX) vs. iShares MSCI Australia ETF (EWA)

Noxopharm Ltd. Business Overview & Revenue Model

Company DescriptionNoxopharm Limited, a drug development company, focuses on developing treatment options for a range of solid tumor cancers and septic shock in Australia and internationally. It primarily develops Veyonda, which is an adjuvant therapy in chemotherapy and radiotherapy for the treatment of late-stage cancers. The company also develops DARRT program that is in Phase 1b/2a for the treatment of metastatic castration-resistant prostate cancer and other solid tumors; LuPIN with combined therapy of Veyonda and 177Lu-PSMA-617 for the treatment of late-stage prostate cancer; IONIC program with Veyonda, which is combined with the Bristol Myers Squibb checkpoint inhibitor Opdivo for the treatment of various solid tumor types; and chemotherapy enhancement program (CEP) combined with carboplatin for patients with refractory solid tumors in the breast, head and neck, lung, prostate, and ovaries. In addition, it develops NOXCOVID Program, a dose escalation and dose expansion study of NOX66 for the treatment of COVID-19 infection. Further, the company develops programs to treat pancreatic cancer and glioblastoma. Noxopharm Limited has a collaboration with Hudson Institute of Medical Research and The Australian National University for the research and development of therapeutic drug against inflammatory disorders. The company was incorporated in 2015 and is based in Chatswood, Australia.
How the Company Makes Moneynull

Noxopharm Ltd. Financial Statement Overview

Summary
Income statement, balance sheet, and cash flow signals are weak: revenue is volatile, 2025 shows negative gross profit and very large operating losses, and net losses remain significant. Cash flow is consistently negative (ongoing cash burn), and the 2025 balance sheet deteriorated materially with higher leverage (debt ~3.6x equity) and much lower equity, increasing funding and financial risk.
Income Statement
18
Very Negative
Revenue has been volatile (down sharply from 2023 to 2024, then up ~20% in 2025), but profitability is weak and deteriorating in the most recent year: 2025 shows negative gross profit and very large operating losses. Net losses remain significant across all years, with margins deeply negative, indicating the core business is not yet economically self-sustaining.
Balance Sheet
32
Negative
The balance sheet has weakened materially in 2025 as debt rose to ~2.48M while equity fell to ~0.69M, pushing leverage high (debt is ~3.6x equity). Returns on equity are strongly negative due to ongoing losses. Earlier years showed lower leverage, but the latest period signals higher financial risk and reduced balance-sheet flexibility.
Cash Flow
20
Very Negative
Cash burn remains heavy, with operating and free cash flow both negative each year. While 2025 free cash flow improved versus the prior year, it is still meaningfully negative, and cash generation does not support the current loss profile. Overall, the company appears reliant on external funding to sustain operations.
BreakdownJun 2025Jun 2024Jun 2023Jun 2022Jun 2021
Income Statement
Total Revenue2.82M2.40M6.01M5.43M5.61M
Gross Profit-1.45M-534.81K5.86M5.17M5.35M
EBITDA-5.38M-5.95M-20.85M-23.70M-5.85M
Net Income-4.88M-3.58M-15.06M-18.67M-9.35M
Balance Sheet
Total Assets4.58M6.78M10.13M26.59M47.85M
Cash, Cash Equivalents and Short-Term Investments1.55M2.32M3.01M14.01M26.80M
Total Debt2.48M0.000.00160.62K349.31K
Total Liabilities3.89M1.29M1.06M2.48M7.08M
Stockholders Equity689.96K5.50M9.07M24.12M40.78M
Cash Flow
Free Cash Flow-5.82M-684.31K-10.95M-13.73M-8.85M
Operating Cash Flow-5.82M-684.31K-10.95M-13.73M-8.85M
Investing Cash Flow2.48M0.00123.51K0.00225.23K
Financing Cash Flow2.60M0.00-178.09K975.73K28.32M

Noxopharm Ltd. Technical Analysis

Technical Analysis Sentiment
Negative
Last Price0.09
Price Trends
50DMA
0.07
Negative
100DMA
0.08
Negative
200DMA
0.09
Negative
Market Momentum
MACD
>-0.01
Positive
RSI
40.99
Neutral
STOCH
27.27
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For AU:NOX, the sentiment is Negative. The current price of 0.09 is above the 20-day moving average (MA) of 0.06, above the 50-day MA of 0.07, and above the 200-day MA of 0.09, indicating a bearish trend. The MACD of >-0.01 indicates Positive momentum. The RSI at 40.99 is Neutral, neither overbought nor oversold. The STOCH value of 27.27 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for AU:NOX.

Noxopharm Ltd. Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
60
Neutral
AU$48.22M-25.8610.35%2.81%0.65%-9.90%
52
Neutral
AU$89.33M-14.80-40.65%700.00%26.88%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
45
Neutral
AU$8.84M-0.152844.96%46.28%
43
Neutral
AU$18.43M-3.69-157.93%-36.89%
42
Neutral
AU$63.09M-5.28-62.49%10.78%
41
Neutral
AU$130.13M-2.84279.21%0.66%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
AU:NOX
Noxopharm Ltd.
0.06
-0.01
-17.81%
AU:PTX
Prescient Therapeutics Limited
0.06
0.02
36.36%
AU:CHM
Chimeric Therapeutics Ltd.
AU:EZZ
EZZ Life Science Holdings Ltd.
1.03
-0.45
-30.65%
AU:RCE
Recce Pharmaceuticals Ltd.
0.45
0.05
13.64%
AU:ALA
Arovella Therapeutics Limited
0.07
-0.03
-26.00%

Noxopharm Ltd. Corporate Events

Noxopharm Half-Year Loss Widens as Net Tangible Assets Turn Negative
Feb 27, 2026

Noxopharm Limited reported a sharp widening of its half-year loss to $1.84 million for the period ended 31 December 2025, a 49% increase from the prior corresponding period’s $1.24 million loss. The company’s net tangible assets per share fell into negative territory at minus 0.39 cents from 0.24 cents, and no dividends were paid or declared, underscoring ongoing funding needs and the capital-intensive nature of its development-stage operations.

The absence of dividends for both the current and previous half-year periods highlights Noxopharm’s continued focus on reinvesting resources into its pipeline rather than returning capital to shareholders. With no changes in control, associates or joint ventures reported, the results primarily reflect internal cost structures and investment in R&D, leaving investors focused on the company’s ability to translate its spending into future clinical and commercial milestones.

The most recent analyst rating on (AU:NOX) stock is a Hold with a A$0.07 price target. To see the full list of analyst forecasts on Noxopharm Ltd. stock, see the AU:NOX Stock Forecast page.

Noxopharm Issues 15 Million New Shares Under Financing Facility
Feb 27, 2026

Noxopharm Limited has issued 15 million fully paid ordinary shares at an issue price of zero dollars per share under a financing facility announced on 27 February 2026, expanding its capital base without providing a disclosure document to investors. The company stated it remains compliant with its financial reporting and continuous disclosure obligations under the Corporations Act and confirmed there is no excluded information that would affect the market, underscoring regulatory transparency around the new share issuance.

The notice clarifies that the share issue was conducted in accordance with section 708A(5)(e) of the Corporations Act, which allows certain placements without a prospectus, potentially streamlining Noxopharm’s access to funding to support its development programs. While the issue price of zero implies the shares were issued as part of an existing financing arrangement rather than a conventional capital raising, it nonetheless alters the company’s share structure and may have implications for existing shareholders in terms of dilution and future funding flexibility.

The most recent analyst rating on (AU:NOX) stock is a Hold with a A$0.07 price target. To see the full list of analyst forecasts on Noxopharm Ltd. stock, see the AU:NOX Stock Forecast page.

Noxopharm Issues 15 Million New Shares Under Financing Facility
Feb 27, 2026

Noxopharm Ltd has applied for quotation on the ASX of 15 million new ordinary fully paid shares issued on 27 February 2026. The shares were created in connection with a new financing facility, with the share issue and execution of the related facility agreement completed on the same day, indicating the company is bolstering its funding capacity through equity-linked arrangements.

The additional securities expand Noxopharm’s quoted share base and provide access to capital that can be deployed into its ongoing operations and development programs. This move may dilute existing shareholders but is likely aimed at strengthening the company’s financial position and supporting its strategic and research activities in the biopharmaceutical market.

The most recent analyst rating on (AU:NOX) stock is a Hold with a A$0.07 price target. To see the full list of analyst forecasts on Noxopharm Ltd. stock, see the AU:NOX Stock Forecast page.

Noxopharm Secures $2.8m R&D Rebate to Advance Sofra Clinical Programs
Feb 27, 2026

Noxopharm has received a $2.8 million rebate under the Australian Government’s R&D Tax Incentive scheme for FY2025, bolstering its cash reserves as it advances its Sofra technology platform and HERACLES clinical program. The funding supports preparation for next-phase clinical trials, expanded external collaborations and further development of Sofra-based drug candidates, including SOF-SKN for cutaneous lupus, which targets a global market exceeding US$3.3 billion amid broader growth in autoimmune and immuno-oncology therapeutics.

The most recent analyst rating on (AU:NOX) stock is a Hold with a A$0.07 price target. To see the full list of analyst forecasts on Noxopharm Ltd. stock, see the AU:NOX Stock Forecast page.

Noxopharm Secures Flexible $5m At-the-Market Equity Facility with Acuity Capital
Feb 27, 2026

Noxopharm Limited has entered into an At-the-Market Subscription Agreement with Acuity Capital, securing access to up to $5 million in standby equity capital over a five-year period to July 2031. The facility gives the company full discretion over whether to draw on the funding, the number of shares issued, pricing floors and timing, and can be terminated at any time without penalty, while placing no restrictions on alternative capital-raising avenues.

As security for the arrangement, Noxopharm will place 15 million fully paid ordinary shares from its existing capacity with Acuity Capital at nil cash consideration, with the option to buy back and cancel these shares at no cost upon early termination or maturity, subject to shareholder approval. The flexible structure is designed to provide additional balance sheet support and financial agility as the company advances its Sofra and Chroma platform-based drug development programs in the competitive cancer and autoimmune therapeutics space.

The most recent analyst rating on (AU:NOX) stock is a Hold with a A$0.07 price target. To see the full list of analyst forecasts on Noxopharm Ltd. stock, see the AU:NOX Stock Forecast page.

Noxopharm’s Sofra Platform Science Published in Top Immunology Journal
Feb 10, 2026

Noxopharm has announced that the breakthrough science underpinning its Sofra platform has been published in Nature Immunology, a leading peer-reviewed journal in the field. The paper, led by Professor Michael Gantier of the Hudson Institute with contributions from Noxopharm staff and international collaborators, details a newly discovered anti-inflammatory mechanism that protects against autoimmune disorders.

The research explains how specific RNA fragments can modulate immune sensors TLR7 and TLR8, enabling the development of novel therapeutics such as Noxopharm’s SOF-SKN candidate for autoimmune skin conditions. Endorsement from prominent U.S. oligonucleotide expert Professor Arthur Krieg and the journal’s prestige bolster the scientific credibility of Sofra, potentially enhancing Noxopharm’s industry profile and attracting greater interest from partners and investors as it advances its drug pipeline for diseases like lupus, psoriasis, diabetes and rheumatoid arthritis.

The most recent analyst rating on (AU:NOX) stock is a Hold with a A$0.06 price target. To see the full list of analyst forecasts on Noxopharm Ltd. stock, see the AU:NOX Stock Forecast page.

Noxopharm Clears Key Safety Milestone as HERACLES Trial Concludes and Sofra Platform Gains Global Traction
Jan 30, 2026

Noxopharm reported a strong December quarter, highlighted by the successful completion of dosing in all cohorts of its milestone HERACLES clinical trial evaluating SOF-SKN™, which delivered highly positive safety and tolerability results and clears a key regulatory hurdle ahead of planned Phase II-enabling studies. The company also broadened the potential applications of its Sofra platform through a new Material Transfer Agreement with an overseas partner developing an innovative drug-delivery system for inflammatory bowel disease, secured its first US “first-tier” composition of matter patent protecting its immune-modulatory oligonucleotides for cancer treatment, and received high-profile recognition from the Victorian Government and the scientific community, reinforcing its positioning at the cutting edge of RNA technology and bolstering the platform’s credibility with investors and collaborators.

The most recent analyst rating on (AU:NOX) stock is a Hold with a A$0.07 price target. To see the full list of analyst forecasts on Noxopharm Ltd. stock, see the AU:NOX Stock Forecast page.

Noxopharm Clears Safety Milestone as HERACLES Trial for SOF-SKN Concludes
Jan 20, 2026

Noxopharm has successfully completed the clinical component of its HERACLES trial, reporting that the second and final multiple-dose cohort of its topical drug candidate SOF-SKN was safe and well tolerated across all dosing groups. The positive safety profile, combined with strong participant compliance and rapid trial progression, clears the way for Phase II-enabling studies and drug scale-up, advancing SOF-SKN’s development for cutaneous lupus erythematosus and potentially other autoimmune-related skin diseases. The outcome strengthens Noxopharm’s position in the competitive autoimmune market and supports broader commercial prospects for its Sofra platform, which targets a range of immune-related conditions with significant global market potential.

The most recent analyst rating on (AU:NOX) stock is a Hold with a A$0.07 price target. To see the full list of analyst forecasts on Noxopharm Ltd. stock, see the AU:NOX Stock Forecast page.

Noxopharm Rolls Over $2.6m in Convertible Notes, Flagging Potential Share Dilution
Jan 1, 2026

Noxopharm has issued 2.6 million new convertible notes with a face value of $1 each and 520,000 unlisted options to sophisticated and professional investors, rolling over an equivalent value of maturing notes first issued in January 2025. The notes, which carry 12% annual interest and mature in January 2027, can convert into between about 29.4 million and 41.6 million shares depending on the conversion price, while the attached options carry a separate exercise price; together, these securities will increase the number of instruments on issue and, upon conversion or exercise, dilute existing shareholders, although the transaction does not bring in fresh cash but instead extends the company’s existing convertible funding structure.

The most recent analyst rating on (AU:NOX) stock is a Hold with a A$0.10 price target. To see the full list of analyst forecasts on Noxopharm Ltd. stock, see the AU:NOX Stock Forecast page.

Noxopharm Issues New Unquoted Options and Convertible Notes
Jan 1, 2026

Noxopharm Limited has notified the market of the issue of 520,000 unquoted options, exercisable at A$0.1488 and expiring on 10 September 2027, along with 2.6 million unquoted convertible notes, both dated 2 January 2026. The new options and convertible notes expand the company’s pool of unquoted securities and indicate continued use of structured equity and hybrid instruments to support its financing needs, with potential future dilution and capital structure changes relevant to existing shareholders and investors tracking the company’s funding strategy.

The most recent analyst rating on (AU:NOX) stock is a Hold with a A$0.10 price target. To see the full list of analyst forecasts on Noxopharm Ltd. stock, see the AU:NOX Stock Forecast page.

Noxopharm Redeems 2.6 Million Convertible Notes, Trimming Convertible Debt
Jan 1, 2026

Noxopharm Limited has notified the market that 2.6 million NOXAH convertible notes have ceased following repayment or redemption without conversion, effective 2 January 2026. The cessation of these convertible debt securities indicates a reduction in the company’s outstanding convertible obligations, which may simplify its capital structure and marginally lessen potential future equity dilution for existing shareholders.

The most recent analyst rating on (AU:NOX) stock is a Hold with a A$0.10 price target. To see the full list of analyst forecasts on Noxopharm Ltd. stock, see the AU:NOX Stock Forecast page.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Feb 11, 2026