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Noxopharm Ltd. (AU:NOX)
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Noxopharm Ltd. (NOX) AI Stock Analysis

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AU:NOX

Noxopharm Ltd.

(Sydney:NOX)

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Neutral 42 (OpenAI - 5.2)
Rating:42Neutral
Price Target:
AU$0.07
▼(-18.89% Downside)
The score is driven primarily by weak financial performance—large ongoing losses, negative cash flow, and increased leverage that raises funding and balance-sheet risk. Technicals also weigh on the score with a clear downtrend (below major moving averages and negative MACD), partially offset by oversold indicators. Valuation is difficult to support with a negative P/E and no dividend yield data.
Positive Factors
Focused oncology therapeutic pipeline
A clear, focused business model targeting oncology and adjuncts to radiotherapy/immuno-oncology supports durable strategic clarity. This concentration aligns R&D, regulatory planning and potential partner interest, improving chances of clinical and commercial progress over months.
Proprietary small‑molecule platform and partner orientation
Owning proprietary small‑molecule platforms provides IP-based differentiation and scalability. Active engagement with external partners can de-risk late‑stage development and accelerate commercialization, preserving cash and leveraging partner capabilities over the medium term.
Revenue uptick and free cash flow improvement in 2025
An uptick in revenue alongside improved free cash flow suggests early operational traction and partial progress toward stabilizing cash needs. If maintained, this trend can extend runway, reduce near-term external funding dependence, and validate commercial elements of the model.
Negative Factors
Sustained heavy cash burn
Persistently negative operating and free cash flows mean the company must repeatedly seek external capital. This structurally increases dilution risk, raises financing costs, and can force program prioritization or delays, constraining long‑term R&D and commercialization plans.
Materially weakened balance sheet and high leverage
Sharp rise in leverage and materially reduced equity weaken financial flexibility. High debt relative to equity increases refinancing and covenant risk, reduces ability to absorb trial setbacks, and makes strategic investments or licensing deals more difficult without substantial new funding.
Persistent large losses and deteriorating profitability
Negative gross profit and recurring large operating losses indicate the core business is not yet economically viable. Continued unprofitable operations mean internal cash cannot support growth, making long‑term sustainability dependent on successful trials, partnerships, or frequent external financing.

Noxopharm Ltd. (NOX) vs. iShares MSCI Australia ETF (EWA)

Noxopharm Ltd. Business Overview & Revenue Model

Company DescriptionNoxopharm Limited, a drug development company, focuses on developing treatment options for a range of solid tumor cancers and septic shock in Australia and internationally. It primarily develops Veyonda, which is an adjuvant therapy in chemotherapy and radiotherapy for the treatment of late-stage cancers. The company also develops DARRT program that is in Phase 1b/2a for the treatment of metastatic castration-resistant prostate cancer and other solid tumors; LuPIN with combined therapy of Veyonda and 177Lu-PSMA-617 for the treatment of late-stage prostate cancer; IONIC program with Veyonda, which is combined with the Bristol Myers Squibb checkpoint inhibitor Opdivo for the treatment of various solid tumor types; and chemotherapy enhancement program (CEP) combined with carboplatin for patients with refractory solid tumors in the breast, head and neck, lung, prostate, and ovaries. In addition, it develops NOXCOVID Program, a dose escalation and dose expansion study of NOX66 for the treatment of COVID-19 infection. Further, the company develops programs to treat pancreatic cancer and glioblastoma. Noxopharm Limited has a collaboration with Hudson Institute of Medical Research and The Australian National University for the research and development of therapeutic drug against inflammatory disorders. The company was incorporated in 2015 and is based in Chatswood, Australia.
How the Company Makes MoneyNoxopharm Ltd. generates revenue primarily through the development and commercialization of its drug candidates, particularly those targeting cancer treatment. The company earns money by advancing its proprietary drug technology through clinical trials and obtaining regulatory approvals, which can lead to partnerships with larger pharmaceutical companies or direct commercialization. Additionally, Noxopharm may engage in licensing agreements, where it licenses its technology to other companies in exchange for upfront payments, milestone payments, and royalties on future sales. Strategic partnerships and collaborations with research institutions and other biotech companies can also provide funding and support for their drug development programs, contributing to their revenue streams.

Noxopharm Ltd. Financial Statement Overview

Summary
Income statement and cash flow indicate an early-stage biotech with persistent, sizable losses and ongoing cash burn. 2025 shows negative gross profit and very large operating losses, while free cash flow remains meaningfully negative despite some improvement. Balance sheet risk increased in 2025 as debt rose and equity fell sharply, leaving leverage high and reducing financial flexibility.
Income Statement
18
Very Negative
Revenue has been volatile (down sharply from 2023 to 2024, then up ~20% in 2025), but profitability is weak and deteriorating in the most recent year: 2025 shows negative gross profit and very large operating losses. Net losses remain significant across all years, with margins deeply negative, indicating the core business is not yet economically self-sustaining.
Balance Sheet
32
Negative
The balance sheet has weakened materially in 2025 as debt rose to ~2.48M while equity fell to ~0.69M, pushing leverage high (debt is ~3.6x equity). Returns on equity are strongly negative due to ongoing losses. Earlier years showed lower leverage, but the latest period signals higher financial risk and reduced balance-sheet flexibility.
Cash Flow
20
Very Negative
Cash burn remains heavy, with operating and free cash flow both negative each year. While 2025 free cash flow improved versus the prior year, it is still meaningfully negative, and cash generation does not support the current loss profile. Overall, the company appears reliant on external funding to sustain operations.
BreakdownTTMDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue2.82M2.82M2.40M6.01M5.43M5.61M
Gross Profit-1.45M-1.45M-534.81K5.86M5.17M5.35M
EBITDA-5.38M-5.38M-5.95M-20.85M-23.70M-5.85M
Net Income-4.88M-4.88M-3.58M-15.06M-18.67M-9.35M
Balance Sheet
Total Assets4.58M4.58M6.78M10.13M26.59M47.85M
Cash, Cash Equivalents and Short-Term Investments1.55M1.55M2.32M3.01M14.01M26.80M
Total Debt2.48M2.48M0.000.00160.62K349.31K
Total Liabilities3.89M3.89M1.29M1.06M2.48M7.08M
Stockholders Equity689.96K689.96K5.50M9.07M24.12M40.78M
Cash Flow
Free Cash Flow-5.82M-5.82M-684.31K-10.95M-13.73M-8.85M
Operating Cash Flow-5.82M-5.82M-684.31K-10.95M-13.73M-8.85M
Investing Cash Flow2.48M2.48M0.00123.51K0.00225.23K
Financing Cash Flow2.60M2.60M0.00-178.09K975.73K28.32M

Noxopharm Ltd. Technical Analysis

Technical Analysis Sentiment
Negative
Last Price0.09
Price Trends
50DMA
0.09
Negative
100DMA
0.09
Negative
200DMA
0.09
Negative
Market Momentum
MACD
>-0.01
Positive
RSI
37.76
Neutral
STOCH
33.99
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For AU:NOX, the sentiment is Negative. The current price of 0.09 is above the 20-day moving average (MA) of 0.09, below the 50-day MA of 0.09, and above the 200-day MA of 0.09, indicating a bearish trend. The MACD of >-0.01 indicates Positive momentum. The RSI at 37.76 is Neutral, neither overbought nor oversold. The STOCH value of 33.99 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for AU:NOX.

Noxopharm Ltd. Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
70
Outperform
AU$87.03M12.6927.24%2.81%0.65%-9.90%
52
Neutral
AU$190.86M-7.330.66%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
50
Neutral
AU$88.33M-9.23-49.72%10.78%
45
Neutral
AU$8.84M-469.35%46.28%
44
Neutral
AU$106.91M-13.09-47.98%700.00%26.88%
42
Neutral
AU$23.67M-4.85-157.93%-36.89%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
AU:NOX
Noxopharm Ltd.
0.08
-0.02
-19.00%
AU:PTX
Prescient Therapeutics Limited
0.08
0.03
44.83%
AU:CHM
Chimeric Therapeutics Ltd.
AU:EZZ
EZZ Life Science Holdings Ltd.
1.85
-0.37
-16.74%
AU:RCE
Recce Pharmaceuticals Ltd.
0.66
0.20
41.94%
AU:ALA
Arovella Therapeutics Limited
0.09
-0.11
-55.50%

Noxopharm Ltd. Corporate Events

Noxopharm Rolls Over $2.6m in Convertible Notes, Flagging Potential Share Dilution
Jan 1, 2026

Noxopharm has issued 2.6 million new convertible notes with a face value of $1 each and 520,000 unlisted options to sophisticated and professional investors, rolling over an equivalent value of maturing notes first issued in January 2025. The notes, which carry 12% annual interest and mature in January 2027, can convert into between about 29.4 million and 41.6 million shares depending on the conversion price, while the attached options carry a separate exercise price; together, these securities will increase the number of instruments on issue and, upon conversion or exercise, dilute existing shareholders, although the transaction does not bring in fresh cash but instead extends the company’s existing convertible funding structure.

The most recent analyst rating on (AU:NOX) stock is a Hold with a A$0.10 price target. To see the full list of analyst forecasts on Noxopharm Ltd. stock, see the AU:NOX Stock Forecast page.

Noxopharm Issues New Unquoted Options and Convertible Notes
Jan 1, 2026

Noxopharm Limited has notified the market of the issue of 520,000 unquoted options, exercisable at A$0.1488 and expiring on 10 September 2027, along with 2.6 million unquoted convertible notes, both dated 2 January 2026. The new options and convertible notes expand the company’s pool of unquoted securities and indicate continued use of structured equity and hybrid instruments to support its financing needs, with potential future dilution and capital structure changes relevant to existing shareholders and investors tracking the company’s funding strategy.

The most recent analyst rating on (AU:NOX) stock is a Hold with a A$0.10 price target. To see the full list of analyst forecasts on Noxopharm Ltd. stock, see the AU:NOX Stock Forecast page.

Noxopharm Redeems 2.6 Million Convertible Notes, Trimming Convertible Debt
Jan 1, 2026

Noxopharm Limited has notified the market that 2.6 million NOXAH convertible notes have ceased following repayment or redemption without conversion, effective 2 January 2026. The cessation of these convertible debt securities indicates a reduction in the company’s outstanding convertible obligations, which may simplify its capital structure and marginally lessen potential future equity dilution for existing shareholders.

The most recent analyst rating on (AU:NOX) stock is a Hold with a A$0.10 price target. To see the full list of analyst forecasts on Noxopharm Ltd. stock, see the AU:NOX Stock Forecast page.

Noxopharm Ltd. Announces Director’s Interest Change
Dec 12, 2025

Noxopharm Ltd. has announced a change in the director’s interest, specifically involving Fred Bart, who has acquired 250,000 options and 1,250,000 convertible notes through 4F Investment Pty Limited. This change was approved by shareholders on November 18, 2025, and reflects a strategic move to enhance the company’s financial instruments, potentially impacting its market positioning and shareholder value.

Noxopharm Issues Convertible Notes to Restructure Capital
Dec 12, 2025

Noxopharm Limited has issued 1,250,000 convertible notes and 250,000 unlisted options to 4F Investments Pty Limited, associated with a company director. This financial maneuver, involving a conversion of an unsecured loan into convertible notes, will not bring new cash inflow but will impact the company’s capital structure by potentially increasing the number of shares if the notes are converted. The move is designed to allow the resale of shares without disclosure to retail investors, potentially diluting existing shareholdings and altering the company’s equity distribution.

Noxopharm Ltd. Issues New Equity Securities to Bolster Growth
Dec 11, 2025

Noxopharm Ltd. has announced the issuance of unquoted equity securities, including 250,000 options expiring in 2027 and 1,250,000 convertible notes. This move is part of the company’s financial strategy to support its ongoing operations and growth in the oncology sector, potentially impacting its market position and stakeholder interests.

Noxopharm Advances SOF-SKN™ Clinical Trial for Autoimmune Diseases
Dec 2, 2025

Noxopharm Limited announced the successful completion of the first multiple-dose cohort in the HERACLES clinical trial for SOF-SKN™, a novel drug candidate for autoimmune diseases like cutaneous lupus erythematosus. The trial, which is being conducted in Australia, aims to assess the safety and tolerability of SOF-SKN™ through repeated applications, reflecting real-world usage. The trial’s progression to the second and final cohort underscores the drug’s potential impact on the autoimmune disease therapeutics market, which is projected to grow significantly.

Noxopharm’s AGM Resolutions Passed, Highlighting Growth Potential of Sofra Platform
Nov 18, 2025

Noxopharm Limited announced that all resolutions were passed at its Annual General Meeting, with significant support for the adoption of the Remuneration Report. The company’s Sofra technology platform, which targets inflammatory and autoimmune diseases, holds potential for significant market impact, given the projected growth in the autoimmune disease therapeutics and immuno-oncology markets.

Noxopharm Unveils 2025 AGM Presentation, Showcasing Clinical and Market Advancements
Nov 17, 2025

Noxopharm Limited has released its 2025 AGM Corporate Presentation, highlighting significant progress in its HERACLES clinical trial and the growing market opportunities for its Sofra™ technology in treating inflammation and cancer. The company has achieved a milestone with its first US patent grant and is gaining increased recognition and interest from third parties in its Sofra assets, positioning it well in the multi-billion dollar biotech market.

Noxopharm Advances Sofra™ Platform with Promising Clinical Trials
Nov 17, 2025

Noxopharm Limited’s 2025 AGM highlighted significant progress in advancing its Sofra™ technology platform, particularly with the SOF-SKN™ clinical trial in Australia. This advancement enhances the company’s reputation and attracts external stakeholder interest, evidenced by a US patent grant and support from the Victorian government. The company is well-positioned to capitalize on the growing interest in RNA technology and the rise in autoimmune diseases, while maintaining prudent operational spending and exploring funding opportunities.

Noxopharm Advances HERACLES Trial with SOF-SKN Dosing
Nov 16, 2025

Noxopharm Limited has commenced the second part of its HERACLES clinical trial, administering the first dose of SOF-SKN™, a novel drug candidate for autoimmune diseases like cutaneous lupus erythematosus. This phase aims to evaluate the safety and tolerability of SOF-SKN through repeated dosing, reflecting real-world conditions. The trial’s success could enhance Noxopharm’s position in the regulatory approval process and potentially expand the use of SOF-SKN to other autoimmune-related skin diseases, positioning the company to capture a share of the growing global cutaneous lupus market, valued at over US$3.3 billion.

Noxopharm and UNSW Sydney Collaborate on Inflammation Study with Government Grant
Nov 10, 2025

Noxopharm Limited has announced a collaboration with UNSW Sydney, supported by a TechVoucher grant from the NSW Government, to conduct an early-stage feasibility study on their Sofra™ technology. This study aims to explore the potential of Noxopharm’s anti-inflammatory oligonucleotides to reduce inflammation caused by implants. The initiative highlights the versatility of the Sofra™ platform, which targets a wide range of inflammatory and autoimmune diseases, and underscores Noxopharm’s strategic partnerships to enhance its market positioning in the biotech industry.

Noxopharm Advances HERACLES Trial for Autoimmune Drug SOF-SKN
Nov 4, 2025

Noxopharm Limited has commenced the second phase of its HERACLES clinical trial for SOF-SKN, a new drug candidate aimed at treating autoimmune diseases like cutaneous lupus erythematosus (CLE). The trial, which will test multiple ascending doses, aims to ensure the drug’s safety over repeated applications, potentially accelerating its development timeline by skipping the lowest dose cohorts. This advancement could position Noxopharm favorably within the growing global CLE market, valued at over US$3.3 billion, and further applications of the Sofra technology could extend to other autoimmune and inflammatory diseases.

Noxopharm Advances Sofra Platform with New Collaborations and Promising Trial Results
Oct 30, 2025

Noxopharm Limited has reported significant progress in its September 2025 Quarterly Activities Report, highlighting new collaborations and promising trial results. The company has signed several collaboration agreements with institutions interested in its Sofra technology platform, which is being explored for various inflammatory diseases. A US company, Tezcat Biosciences, has shown promising preclinical results using Noxopharm’s oligonucleotides in a novel drug candidate. Additionally, Noxopharm’s HERACLES clinical trial has demonstrated that its SOF-SKN treatment is safe and well-tolerated, supporting the platform’s potential in treating autoimmune diseases. The extension of convertible notes and access to government rebates further strengthen the company’s financial position.

Noxopharm Secures First US Patent for Sofra™ Technology in Cancer Treatment
Oct 21, 2025

Noxopharm Limited has secured its first US patent for the Sofra™ technology platform, which is designed to harness immune-modulatory oligonucleotides for cancer treatment. This patent protects the structure of Noxopharm’s assets, ensuring the commercial value of their ongoing cancer research. The Sofra platform, developed in collaboration with the Hudson Institute of Medical Research, shows potential for versatile applications in mitigating inflammation and weaponizing the immune system against cancer. This milestone positions Noxopharm favorably in the growing immuno-oncology market, projected to expand significantly in the coming years.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Jan 17, 2026