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Chimeric Therapeutics Ltd. (AU:CHM)
ASX:CHM
Australian Market

Chimeric Therapeutics Ltd. (CHM) AI Stock Analysis

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AU:CHM

Chimeric Therapeutics Ltd.

(Sydney:CHM)

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Neutral 45 (OpenAI - 5.2)
Rating:45Neutral
Price Target:
AU$0.01
▲(10.00% Upside)
The score is primarily constrained by weak financial performance: ongoing losses, continued cash burn, and a materially reduced equity cushion. Offsetting factors include high recent gross margins and no reported debt. Limited technical data prevents a stronger technical read, and valuation is challenged by negative earnings and no dividend support.
Positive Factors
FDA Orphan Drug Designation
The FDA Orphan Drug Designation provides market exclusivity and tax incentives, strengthening Chimeric's competitive position in cancer therapy.
Promising Clinical Trial Results
Promising trial results enhance Chimeric's reputation and potential for successful therapies, supporting long-term growth in the oncology market.
R&D Tax Incentive
The R&D tax incentive boosts financial resources for innovation, aiding Chimeric's development of new therapies and reinforcing its market position.
Negative Factors
Ongoing Cash Burn
Continued cash burn indicates reliance on external funding, which could lead to dilution and financial instability if not addressed.
Shrinking Equity Base
A reduced equity base limits financial flexibility and increases funding risks, potentially affecting Chimeric's ability to sustain operations.
Material Capital Raising
While raising capital strengthens finances, it risks significant shareholder dilution, impacting investor returns and market perception.

Chimeric Therapeutics Ltd. (CHM) vs. iShares MSCI Australia ETF (EWA)

Chimeric Therapeutics Ltd. Business Overview & Revenue Model

Company DescriptionChimeric Therapeutics Limited, a clinical stage cell therapy company, develops and commercializes a range of cell therapies in oncology in Australia. The company develops CHM 0201 (core NK platform) that is in phase I clinical trial for treating solid tumors and hematological malignancies; and CHM 1101 (CLTX CAR T), which is in phase I clinical trial for treating patients with MMP2+ recurrent or progressive glioblastoma. It is also developing CHM 0301 for blood cancers; CHM 1301 (CLTX CAR NK) and CHM 2301 (CDH17 CAR NK) for solid tumors; CHM 1101 (CLTX CAR T) for melanoma, colorectal, and prostate; and CHM 2101 (CDH17 CAR T) for neuroendocrine, colorectal, pancreatic, and gastric. The company was incorporated in 2020 and is based in Carlton, Australia.
How the Company Makes MoneyChimeric Therapeutics makes money primarily through the development and commercialization of its CAR-T cell therapy products. The company's revenue streams include licensing agreements, where it partners with other pharmaceutical companies to co-develop or market its therapies. Additionally, Chimeric Therapeutics may receive milestone payments and royalties from these partnerships as their products advance through clinical trials and reach the market. Furthermore, the company might engage in research collaborations and secure grants or funding from governmental or non-governmental organizations, contributing to its financial resources.

Chimeric Therapeutics Ltd. Financial Statement Overview

Summary
High recent gross margins and improved losses versus 2023 are positives, and no reported debt reduces balance-sheet risk. However, the company remains deeply unprofitable with persistent operating cash outflows and negative free cash flow, and the equity base has shrunk materially—raising ongoing funding/dilution risk.
Income Statement
28
Negative
Revenue has been volatile—strong growth in 2022 and a rebound in 2025, but a clear step-down versus 2024. Gross margin is high in the most recent years (2024–2025), suggesting good economics on reported revenue, but the company remains deeply unprofitable: EBIT and net margins are significantly negative across all periods, reflecting a business still in heavy investment mode. Losses have improved materially from 2023 levels, but profitability is not yet in sight based on the current trajectory.
Balance Sheet
46
Neutral
Leverage appears manageable overall with no debt reported in 2025 (and several prior years), which reduces financial risk. However, the equity base has shrunk substantially over time (from ~25.7M in 2022 to ~2.0M in 2025), consistent with ongoing losses and potential dilution/consumption of capital. Returns on equity are strongly negative, highlighting that shareholder capital is not currently generating earnings, and the reduced equity cushion limits flexibility if losses persist.
Cash Flow
22
Negative
Cash generation is weak: operating cash flow is consistently negative, and TTM (Trailing-Twelve-Months) free cash flow is also negative, indicating continued cash burn to fund operations. Free cash flow swung sharply year-to-year (including a near-breakeven 2024), but 2025 reverts to meaningfully negative levels. While cash burn has improved versus 2023, the business still relies on external funding unless operating losses and cash outflows narrow further.
BreakdownTTMDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue9.12M3.97M7.46M0.002.62M2.65K
Gross Profit8.70M3.12M7.45M3.54M1.67M-844.31K
EBITDA-7.37M-9.08M-11.30M-28.59M-13.62M-14.26M
Net Income-6.64M-10.43M-12.53M-25.92M-15.90M-15.11M
Balance Sheet
Total Assets21.57M21.57M15.27M22.38M34.88M36.50M
Cash, Cash Equivalents and Short-Term Investments5.76M5.76M3.05M5.37M18.38M22.41M
Total Debt0.000.003.59M0.000.000.00
Total Liabilities19.60M19.60M12.80M16.71M9.17M11.37M
Stockholders Equity1.97M1.97M2.47M5.66M25.71M25.13M
Cash Flow
Free Cash Flow-4.96M-7.28M10.11K-16.43M-13.69M-14.15M
Operating Cash Flow-4.96M-7.28M-7.54M-16.32M-13.15M-8.84M
Investing Cash Flow0.000.000.00-112.19K-577.86K-5.30M
Financing Cash Flow10.05M10.05M8.26M253.38K9.50M36.54M

Chimeric Therapeutics Ltd. Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
52
Neutral
AU$186.52M-6.660.66%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
50
Neutral
AU$79.92M-8.35-49.72%10.78%
48
Neutral
AU$9.02M-19.05-8.72%71.10%
45
Neutral
AU$11.05M-469.35%46.28%
44
Neutral
AU$105.70M-13.24-47.98%700.00%26.88%
42
Neutral
AU$23.38M-4.61-157.93%-36.89%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
AU:CHM
Chimeric Therapeutics Ltd.
AU:PTX
Prescient Therapeutics Limited
0.07
0.02
27.27%
AU:IXC
Invex Therapeutics Ltd.
0.13
0.06
85.71%
AU:NOX
Noxopharm Ltd.
0.08
-0.01
-14.44%
AU:RCE
Recce Pharmaceuticals Ltd.
0.56
0.11
23.08%
AU:ALA
Arovella Therapeutics Limited
0.09
-0.10
-54.74%

Chimeric Therapeutics Ltd. Corporate Events

Chimeric Therapeutics Issues 309.9 Million New Shares Under Regulatory Notice
Jan 7, 2026

Chimeric Therapeutics has issued 309,900,722 new ordinary shares on 7 January 2026, expanding its share capital without providing a prospectus-style disclosure under the Corporations Act provisions governing fundraising. The company affirmed it is up to date with its financial reporting and continuous disclosure obligations and stated that there is no excluded information requiring disclosure, signalling regulatory compliance around the capital issuance for existing and prospective investors.

The most recent analyst rating on (AU:CHM) stock is a Hold with a A$0.01 price target. To see the full list of analyst forecasts on Chimeric Therapeutics Ltd. stock, see the AU:CHM Stock Forecast page.

Chimeric Therapeutics Seeks ASX Quotation for 309.9 Million New Shares
Jan 7, 2026

Chimeric Therapeutics Limited has applied to the ASX for quotation of 309,900,722 ordinary fully paid shares, to be issued and quoted from 7 January 2026 under its existing ticker CHM. The large issuance, tied to previously announced transactions, will significantly expand the company’s quoted share base, potentially affecting liquidity and ownership structure for investors as the new securities commence trading.

The most recent analyst rating on (AU:CHM) stock is a Hold with a A$0.01 price target. To see the full list of analyst forecasts on Chimeric Therapeutics Ltd. stock, see the AU:CHM Stock Forecast page.

Chimeric Therapeutics Announces Change in Substantial Holding After Share Placement
Jan 5, 2026

Chimeric Therapeutics has disclosed that Paul Hopper has ceased to be a substantial shareholder in the company as of 31 December 2025, following the filing of a statutory notice. The change in substantial holding status arises solely from dilution of Hopper’s percentage interest due to a recent share placement, with the company emphasising that there has been no on-market or off-market sale of shares by him, indicating that his absolute shareholding remains unchanged while the company’s expanded capital base has altered ownership proportions.

The most recent analyst rating on (AU:CHM) stock is a Hold with a A$0.01 price target. To see the full list of analyst forecasts on Chimeric Therapeutics Ltd. stock, see the AU:CHM Stock Forecast page.

Chimeric Therapeutics Issues 466.7 Million New Shares Under Section 708A
Dec 31, 2025

Chimeric Therapeutics has issued 466,666,665 new ordinary shares on 31 December 2025, expanding its share capital without providing a prospectus or other disclosure document, in reliance on the provisions of section 708A of the Corporations Act. The company affirmed that it is up to date with its financial reporting and continuous disclosure obligations and stated there is no excluded information requiring disclosure, signalling that the large capital issuance is being conducted within existing regulatory frameworks and without undisclosed market-sensitive information for investors.

The most recent analyst rating on (AU:CHM) stock is a Hold with a A$0.01 price target. To see the full list of analyst forecasts on Chimeric Therapeutics Ltd. stock, see the AU:CHM Stock Forecast page.

Chimeric Therapeutics Seeks ASX Quotation for 466.7 Million New Shares
Dec 31, 2025

Chimeric Therapeutics Limited has applied for quotation on the ASX of 466,666,665 new fully paid ordinary shares, to be issued on 31 December 2025 under its existing capital management program. The substantial increase in quoted securities signals a significant capital move that may affect the company’s ownership structure and liquidity, with implications for existing shareholders as the enlarged share base begins trading on the market.

The most recent analyst rating on (AU:CHM) stock is a Hold with a A$0.01 price target. To see the full list of analyst forecasts on Chimeric Therapeutics Ltd. stock, see the AU:CHM Stock Forecast page.

Chimeric Therapeutics Plans Major Capital Raise via Shares, Notes and Options
Dec 23, 2025

Chimeric Therapeutics Limited has announced a proposed capital raising via a placement and related securities issue, seeking to issue up to 690,099,278 new fully paid ordinary shares, 4,000,000 convertible notes, and a substantial number of options expiring in 2029 and 2030. The transaction, slated for completion around 11 March 2026, would significantly expand the company’s capital base and provide additional funding flexibility, potentially diluting existing shareholders but strengthening its financial position to support ongoing operations and future growth initiatives.

Chimeric Therapeutics Issues 16.7 Million Unquoted Options Under Employee Incentive Scheme
Dec 19, 2025

Chimeric Therapeutics Limited has notified the market of the issue of 16,667,000 unquoted options under an employee incentive scheme, with various exercise prices and expiry dates, effective 12 December 2025. The additional unquoted equity securities expand the company’s pool of staff incentives, aligning employee remuneration with shareholder interests and potentially impacting future capital structure depending on option exercise and subsequent share issuance.

Chimeric Therapeutics Grants 16.7 Million Unlisted Options to Director Miles Prince
Dec 19, 2025

Chimeric Therapeutics has disclosed a change in director Miles Prince’s interests, confirming the issue of 16,667,000 unlisted options to him following shareholder approval at the company’s 25 November 2025 Annual General Meeting. The grant, made for nil cash consideration and without any disposal of existing securities, increases Prince’s direct exposure to the company’s equity and further aligns his incentives with shareholders, signalling continued confidence in Chimeric’s strategic direction in the competitive oncology biotech space.

Chimeric Therapeutics Shares Halted Ahead of Material Capital Raising Announcement
Dec 19, 2025

Chimeric Therapeutics has requested and been granted a trading halt on its securities by the ASX as it prepares to announce details of a material capital raising. The halt will remain in place until the anticipated announcement is released or until the start of normal trading on 23 December 2025, signalling that the company is undertaking a significant funding initiative that could influence its capital structure and near-term strategic activities.

Chimeric Therapeutics’ CHM 1107 Receives FDA Orphan Drug Designation for Gastric Cancer
Dec 7, 2025

Chimeric Therapeutics announced that its novel CAR-T cell therapy, CHM 1107, has been granted Orphan Drug Designation by the FDA for the treatment of gastric cancer. This designation provides the company with incentives such as tax credits and potential market exclusivity, enhancing its position in the cell therapy industry and addressing significant unmet medical needs in gastric cancer treatment.

Chimeric Therapeutics Announces Board Changes and Promising Trial Results
Nov 27, 2025

Chimeric Therapeutics announced significant board changes following shareholder feedback from its recent AGM, including the appointment of a new Chairperson and a Non-Executive Director nominated by a major shareholder. The company is optimistic about its future as it progresses its CHM CDH17 Phase 1/2 trial, which is showing promising results in tumor shrinkage and disease control, with more data expected soon.

Chimeric Therapeutics Announces Director Resignation
Nov 26, 2025

Chimeric Therapeutics Ltd. announced the resignation of Paul Hopper from his position as a director, effective November 25, 2025. This change in the board may impact the company’s strategic direction and investor confidence, given Hopper’s significant holdings of 21,232,142 ordinary shares and 31,580,882 options. The transition could influence the company’s operations and its positioning in the competitive biotechnology market.

Chimeric Therapeutics AGM Results and Leadership Changes
Nov 25, 2025

Chimeric Therapeutics Ltd. announced the results of its Annual General Meeting, where all resolutions were conducted via poll. A significant outcome was the ‘first strike’ against the Remuneration Report under the Corporations Act, indicating shareholder dissatisfaction with executive pay. Additionally, Paul Hopper retired as Executive Chairman, with Phillip Hains appointed as Acting Chair until a new Chair is announced. The meeting also saw the election of Professor Henry Miles Prince as a Director and approval for issuing incentive options to him, while similar options for Paul Hopper were not approved. These developments may impact the company’s governance and strategic direction.

Chimeric Therapeutics Highlights Risks in Clinical Trials and Regulatory Processes
Nov 24, 2025

Chimeric Therapeutics Ltd. has issued a news release containing forward-looking statements, highlighting potential risks and uncertainties related to their clinical trials and regulatory approvals. The announcement underscores the company’s commitment to advancing its cell therapy solutions while acknowledging the challenges and costs associated with clinical trials and regulatory processes.

Chimeric Therapeutics Secures $4.5M R&D Tax Incentive to Boost Cancer Therapy Development
Nov 24, 2025

Chimeric Therapeutics has received a $4.5 million R&D tax incentive from the Australian Government, recognizing its research and development activities in 2025. This financial boost supports Chimeric’s ongoing efforts in advancing its cell therapy programs, potentially enhancing its position in the oncology treatment market and benefiting stakeholders through continued innovation in cancer therapies.

Chimeric Therapeutics Reports Promising Results in CHM CDH17 Clinical Trial
Nov 13, 2025

Chimeric Therapeutics announced promising results from its CHM CDH17 Phase 1/2 clinical trial, showing 75% disease control among evaluable subjects at 28 days. The trial, which focuses on advanced colorectal cancer, gastric cancer, and gastrointestinal NETs, demonstrated stable disease in all patients treated at Dose Level 2, with one patient maintaining stable disease for nearly a year without additional therapy. This progress underscores the potential impact of CHM CDH17 as a novel CAR-T cell therapy targeting CDH17, a biomarker linked to poor prognosis in gastrointestinal tumors.

Chimeric Therapeutics Temporarily Halts Phase 1b Trial Due to Supply Chain Issues
Nov 13, 2025

Chimeric Therapeutics has temporarily suspended its CHM CORE-NK + Vactosertib Phase 1b clinical trial due to supply chain issues unrelated to the treatment itself. The trial aims to treat patients with advanced colorectal and blood cancers, and the company expects to resolve the issue soon, potentially impacting its operations and stakeholder confidence.

Chimeric Therapeutics Reports Promising ADVENT-AML Trial Results
Nov 6, 2025

Chimeric Therapeutics Limited responded to an ASX query regarding the ADVENT-AML clinical trial results. The company disclosed that no dose-limiting toxicities were observed, and CORE-NK cells persisted in patients’ blood. Notably, 57% of high-risk frontline subjects showed clinical responses, with two new complete responses in AML. This information, although not initially disclosed, is considered to have a potential material impact on the company’s securities when combined with additional new data.

Chimeric Therapeutics Advances Clinical Trials and Expands Leadership
Oct 31, 2025

Chimeric Therapeutics has reported significant progress in its CHM CDH17 Phase 1/2 clinical trial, advancing to dose level 2 with promising safety and efficacy results. The trial has shown manageable safety profiles and encouraging disease control in patients, with notable tumor size reductions in colorectal and neuroendocrine cancers. Additionally, the company has strengthened its leadership by appointing Professor Miles Prince as a Non-Executive Director and has signed a local manufacturing agreement with the New South Wales Government, potentially enhancing its operational capabilities.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Dec 30, 2025