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Acrux Limited (AU:ACR)
ASX:ACR

Acrux (ACR) AI Stock Analysis

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AU:ACR

Acrux

(Sydney:ACR)

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Neutral 42 (OpenAI - 5.2)
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Neutral 42 (OpenAI - 5.2)
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Neutral 42 (OpenAI - 5.2)
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Neutral 42 (OpenAI - 5.2)
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Neutral 42 (OpenAI - 5.2)
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Neutral 42 (OpenAI - 5.2)
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Neutral 42 (OpenAI - 5.2)
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Neutral 42 (OpenAI - 5.2)
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Neutral 42 (OpenAI - 5.2)
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Neutral 42 (OpenAI - 5.2)
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Neutral 42 (OpenAI - 5.2)
Rating:42Neutral
Price Target:
AU$0.01
▼(-40.00% Downside)
Action:ReiteratedDate:11/28/25
Acrux's overall stock score is primarily impacted by its weak financial performance, characterized by persistent losses and high leverage. Technical analysis provides mixed signals, with no strong momentum. Valuation metrics are concerning, with a negative P/E ratio and no dividend yield. These factors collectively suggest a high-risk investment with significant challenges ahead.
Positive Factors
Licensing / Royalty Business Model
Acrux's partner-focused licensing and royalty model is structurally durable: it reduces the need for a large salesforce and leverages partners' regulatory and commercial capabilities, allowing revenue to be earned via recurring royalties and milestone timing rather than ongoing fixed-cost selling investments.
Revenue growth and gross margin improvement
Sustained top-line expansion combined with a sharply improved gross margin indicates successful commercial execution or favorable product mix through partners; if maintained, these trends can underpin scalable profitability as royalties and milestone receipts grow relative to direct costs.
Positive equity base provides balance-sheet buffer
Maintaining positive equity gives Acrux a structural cushion against shocks and supports ongoing licensing negotiations and R&D funding; it preserves creditor and partner confidence, making it easier to access contingent financing or partner-funded development over the medium term.
Negative Factors
High financial leverage
A 3.55 debt-to-equity ratio is structurally risky: it increases interest and covenant pressure, reduces financial flexibility for R&D or to support partners, and heightens refinancing risk if cash generation stays weak, which can constrain long-term strategic options.
Negative operating and free cash flow
Persistent negative operating and free cash flows signal structural liquidity pressure: the business relies on milestone receipts, financing, or asset sales to fund operations, limiting reinvestment capacity and making long-term product development and partner commitments more tenuous.
Ongoing negative profitability metrics
Despite revenue gains, consistent net losses and negative return on equity reflect underlying cost structure or one-off items that have not been resolved; prolonged unprofitability undermines capital formation, impedes scaling, and increases reliance on external funding.

Acrux (ACR) vs. iShares MSCI Australia ETF (EWA)

Acrux Business Overview & Revenue Model

Company DescriptionAcrux Limited (ACR) is a biopharmaceutical company based in Australia, specializing in the development and commercialization of innovative drug delivery technologies and pharmaceutical products. The company operates primarily in the healthcare sector, focusing on transdermal delivery systems, which enable medications to be absorbed through the skin. Acrux's core products include various transdermal patches and formulations designed to improve patient adherence and therapeutic outcomes in areas such as hormone replacement therapy and pain management.
How the Company Makes MoneyAcrux has historically generated revenue primarily through (1) royalties on net sales of products commercialized by partners that use Acrux-developed formulations and/or intellectual property, (2) upfront payments and milestone payments under licensing and collaboration agreements tied to development, regulatory approvals, and commercial performance, and (3) other licensing-related receipts (such as technology access fees) where applicable. In this model, Acrux typically does not rely solely on building its own large salesforce; instead, it seeks partners with established commercial and regulatory capabilities to market products, while Acrux earns a contracted share of economics (royalties) and contingent payments (milestones). Specific product-level revenue contributions, current material partnerships, and the present mix between royalties, milestones, and any direct product sales are null.

Acrux Financial Statement Overview

Summary
Acrux faces significant financial challenges, characterized by persistent losses, high leverage, and negative cash flows. While there are some improvements in revenue growth and gross profit margin, the company's profitability and cash flow issues pose substantial risks. The high debt-to-equity ratio and negative return on equity further highlight financial instability.
Income Statement
30
Negative
Acrux's income statement reveals significant challenges, with consistently negative net profit margins and EBIT margins over the years. Although there was a notable revenue growth of 48.38% in 2025, the company still reported a substantial net loss. The gross profit margin improved to 100% in 2025, but this is overshadowed by the negative profitability metrics, indicating operational inefficiencies and high costs relative to revenue.
Balance Sheet
40
Negative
The balance sheet shows a concerning debt-to-equity ratio of 3.55 in 2025, indicating high leverage and potential financial risk. Return on equity is negative, reflecting ongoing losses. The equity ratio has decreased, suggesting a weakening financial position. Despite these issues, the company has managed to maintain a positive equity base, which provides some stability.
Cash Flow
35
Negative
Cash flow analysis highlights negative operating and free cash flows, with a slight improvement in free cash flow growth in 2025. The operating cash flow to net income ratio is negative, indicating cash flow challenges. The free cash flow to net income ratio is close to 1, suggesting that cash outflows are closely aligned with net losses, which is a concern for liquidity.
BreakdownJun 2025Jun 2024Jun 2023Jun 2022Jun 2021
Income Statement
Total Revenue1.19M5.09M8.43M1.72M1.34M
Gross Profit1.19M1.13M1.95M-4.65M-7.59M
EBITDA-5.17M-8.06M-2.79M-12.29M-15.59M
Net Income-5.95M-5.80M-764.00K-9.83M-12.63M
Balance Sheet
Total Assets7.22M8.96M14.30M15.27M24.20M
Cash, Cash Equivalents and Short-Term Investments863.00K2.94M6.23M5.83M15.27M
Total Debt3.63M3.70M2.35M2.08M2.23M
Total Liabilities6.20M5.69M5.60M6.18M5.73M
Stockholders Equity1.02M3.28M8.70M9.09M18.47M
Cash Flow
Free Cash Flow-5.48M-4.58M584.00K-9.28M-11.52M
Operating Cash Flow-5.47M-4.30M703.00K-8.82M-11.41M
Investing Cash Flow-5.00K-276.00K-119.00K-465.00K-102.00K
Financing Cash Flow3.39M1.29M-183.00K-155.00K17.58M

Acrux Technical Analysis

Technical Analysis Sentiment
Negative
Last Price0.02
Price Trends
50DMA
0.01
Negative
100DMA
0.01
Negative
200DMA
0.02
Negative
Market Momentum
MACD
>-0.01
Positive
RSI
38.31
Neutral
STOCH
>-0.01
Positive
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For AU:ACR, the sentiment is Negative. The current price of 0.02 is above the 20-day moving average (MA) of 0.01, above the 50-day MA of 0.01, and above the 200-day MA of 0.02, indicating a bearish trend. The MACD of >-0.01 indicates Positive momentum. The RSI at 38.31 is Neutral, neither overbought nor oversold. The STOCH value of >-0.01 is Positive, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for AU:ACR.

Acrux Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
48
Neutral
AU$7.89M-3.15-17.07%71.10%
45
Neutral
AU$8.84M-0.152844.96%46.28%
43
Neutral
AU$25.75M-6.84-49.25%
42
Neutral
AU$4.93M9.33-211.88%-76.63%12.00%
40
Underperform
AU$30.26M-5.38-19.10%-672.73%
39
Underperform
AU$17.08M-1.59-91.88%-93.83%20.00%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
AU:ACR
Acrux
0.01
-0.01
-50.00%
AU:1AI
Living Cell Technologies
0.02
<0.01
50.00%
AU:IXC
Invex Therapeutics Ltd.
0.11
0.03
50.00%
AU:CHM
Chimeric Therapeutics Ltd.
AU:NSB
Neuroscientific Biopharmaceuticals Ltd.
0.09
0.05
127.50%
AU:MEM
Memphasys Ltd
0.01
0.00
0.00%

Acrux Corporate Events

Acrux Secures $0.55m Advance on FY26 R&D Tax Incentive to Support HRT Development
Mar 11, 2026

Acrux Limited has secured a second advance of $0.55 million against its FY26 R&D Tax Incentive from Radium Capital, covering eligible R&D conducted between 1 October 2025 and 28 February 2026. The funding represents about 80% of the estimated rebate for that four-month period and is obtained through a short-term facility that provides earlier access to tax incentive cash flows, improving alignment with spending.

Following confirmation from the U.S. Food and Drug Administration on the regulatory pathway for Acrux’s Hormone Replacement Therapy program, the company plans to use the funds to support development of its HRT pipeline and manage working capital needs. The terms of this advance are unchanged from the prior FY26 drawdown, underscoring a consistent funding approach that helps sustain R&D momentum and operational flexibility while Acrux progresses key topical pharmaceutical products toward commercialisation.

The most recent analyst rating on (AU:ACR) stock is a Hold with a A$0.01 price target. To see the full list of analyst forecasts on Acrux stock, see the AU:ACR Stock Forecast page.

Acrux Performance Rights Lapse After Reaching Expiry
Feb 26, 2026

Acrux Limited has notified the market that 910,769 performance rights, trading under the ASX security code ACRAT, have lapsed. The cessation follows the expiry of these rights without being exercised or converted, resulting in a reduction of the company’s outstanding equity-linked securities.

The move slightly simplifies Acrux’s capital structure and may marginally reduce potential future dilution for existing shareholders. While the announcement is procedural, it clarifies the current level of issued capital and the status of incentive-related instruments on the company’s register.

The most recent analyst rating on (AU:ACR) stock is a Sell with a A$0.01 price target. To see the full list of analyst forecasts on Acrux stock, see the AU:ACR Stock Forecast page.

Acrux Posts Strong Half-Year Profit Rebound Despite Lower Asset Backing
Feb 25, 2026

Acrux Limited reported a strong improvement in financial performance for the half-year ended 31 December 2025, with revenues from ordinary activities rising 109% to A$3.57 million. Net profit attributable to members also more than doubled to A$165,000, although no dividends were declared for the period.

Despite the profit rebound, the company’s net tangible asset backing per share fell to 0.21 cents from 0.67 cents a year earlier, indicating a weaker asset base on a per-share basis. The reviewed half-year figures highlight both the company’s accelerating operational momentum and a capital structure that investors will watch closely as Acrux pursues further growth.

The most recent analyst rating on (AU:ACR) stock is a Sell with a A$0.01 price target. To see the full list of analyst forecasts on Acrux stock, see the AU:ACR Stock Forecast page.

Acrux Lifts Cash and Revenue as It Refocuses Portfolio on Higher-Value Therapies
Jan 28, 2026

Acrux reported a solid December 2025 quarter, with customer receipts rising to $1.807 million and cash and cash equivalents increasing to $0.946 million, supported by strong growth in profit-share and royalty income as its U.S. topical generics portfolio completed its first full revenue periods since launch. The company strengthened its portfolio by divesting the underperforming Prilocaine/Lidocaine cream—which generated $0.822 million and removed associated liabilities—while expanding fee-for-service work for external partners, tightening operating costs, and reallocating R&D spending from mature generics toward higher-potential HRT and next-generation drug delivery programs, moves that collectively aim to bolster margins, de-risk returns in a competitive U.S. generics market, and reposition Acrux for longer-term growth.

The most recent analyst rating on (AU:ACR) stock is a Sell with a A$0.01 price target. To see the full list of analyst forecasts on Acrux stock, see the AU:ACR Stock Forecast page.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Nov 28, 2025