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Apellis Pharmaceuticals Inc (APLS)
NASDAQ:APLS
US Market
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Apellis Pharmaceuticals (APLS) Earnings Dates, Call Summary & Reports

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Earnings Data

Report Date
Mar 04, 2026
After Close (Confirmed)
Period Ending
2025 (Q4)
Consensus EPS Forecast
-0.37
Last Year’s EPS
-0.29
Same Quarter Last Year
Moderate Buy
Based on 16 Analysts Ratings

Earnings Call Summary

Q3 2025
Earnings Call Date:Oct 30, 2025|
% Change Since:
|
Earnings Call Sentiment|Neutral
The earnings call reflected significant progress with the FDA approval of EMPAVELI and strong market leadership of SYFOVRE. However, challenges in SYFOVRE revenue due to free drug programs and operational challenges in patient access were notable concerns.
Company Guidance
During the Apellis Pharmaceuticals Third Quarter 2025 Earnings Conference Call, the company provided guidance indicating significant progress and strategic initiatives to drive future growth. The key highlight was the FDA approval of EMPAVELI for C3 glomerulopathy and IC-MPGN, expanding its market by approximately 5,000 patients. This approval is expected to deliver meaningful results across proteinuria reduction, eGFR stabilization, and substantial C3 deposit clearance. Apellis is also preparing to launch EMPAVELI with a target of 225 cumulative patient start forms by the end of the year and has scaled its field teams to 100 people to cover U.S. nephrologists. For SYFOVRE, which has demonstrated a 4% injection growth this quarter, the company anticipates steady growth driven by new tools and market education initiatives over the next 12 to 18 months. Financially, total revenue for the quarter was $459 million, including $151 million from SYFOVRE and $27 million from EMPAVELI across all indications, with a noted $15 million revenue headwind from free goods. Apellis remains confident in its long-term market strategy and the transformative impact of its therapies, supported by a strong cash position of $475 million, allowing for further pipeline advancements.
FDA Approval of EMPAVELI
EMPAVELI was approved for treating patients 12 years and older with C3 glomerulopathy (C3G) or primary immune complex membranoproliferative glomerulonephritis (IC-MPGN), expanding the addressable market by approximately 5,000 patients.
SYFOVRE Market Leadership
SYFOVRE maintained its leading position, accounting for an estimated 52% of new patient starts and more than 60% of the overall market.
Strong Financial Performance
Total revenue for the third quarter was $459 million, including a $275 million upfront payment from Sobi.
Positive EMPAVELI Launch Feedback
The market feedback for EMPAVELI has been exceptionally positive, highlighting its ease of use and the convenience of twice-weekly dosing.
Continued Injection Growth for SYFOVRE
SYFOVRE experienced a 4% growth in total estimated injections during the quarter.

Apellis Pharmaceuticals (APLS) Earnings, Revenues Date & History

The upcoming earnings date is based on a company’s previous reporting, and may be updated when the actual date is announced

APLS Earnings History

Report Date
Fiscal Quarter
Forecast / EPS
Last Year's EPS
EPS YoY Change
Press Release
Slides
Play Transcript
Mar 04, 2026
2025 (Q4)
-0.37 / -
-0.29
Oct 30, 2025
2025 (Q3)
1.58 / 1.67
-0.46463.04% (+2.13)
Jul 31, 2025
2025 (Q2)
-0.47 / -0.33
-0.3-10.00% (-0.03)
May 07, 2025
2025 (Q1)
-0.34 / -0.74
-0.54-37.04% (-0.20)
Feb 28, 2025
2024 (Q4)
-0.37 / -0.29
-0.7360.27% (+0.44)
Nov 05, 2024
2024 (Q3)
-0.29 / -0.46
-1.1760.68% (+0.71)
Aug 01, 2024
2024 (Q2)
-0.31 / -0.30
-1.0270.59% (+0.72)
May 07, 2024
2024 (Q1)
-0.48 / -0.54
-1.5665.38% (+1.02)
Feb 27, 2024
2023 (Q4)
-0.73 / -0.73
-1.551.33% (+0.77)
Nov 01, 2023
2023 (Q3)
-0.99 / -1.17
-1.7533.14% (+0.58)
The table shows recent earnings report dates and whether the forecast was beat or missed. See the change in forecast and EPS from the previous year.
Beat
Missed

APLS Earnings-Related Price Changes

Report Date
Price 1 Day Before
Price 1 Day After
Percentage Change
Oct 30, 2025
$30.05$20.73-31.01%
Jul 31, 2025
$19.00$22.34+17.58%
May 07, 2025
$19.12$17.99-5.91%
Feb 28, 2025
$26.00$25.15-3.27%
Earnings announcements can affect a stock’s price. This table shows the stock's price the day before and the day after recent earnings reports, including the percentage change.

FAQ

When does Apellis Pharmaceuticals Inc (APLS) report earnings?
Apellis Pharmaceuticals Inc (APLS) is schdueled to report earning on Mar 04, 2026, After Close (Confirmed).
    What is Apellis Pharmaceuticals Inc (APLS) earnings time?
    Apellis Pharmaceuticals Inc (APLS) earnings time is at Mar 04, 2026, After Close (Confirmed).
      Where can I see when companies are reporting earnings?
      You can see which companies are reporting today on our designated earnings calendar.
        What companies are reporting earnings today?
        You can see a list of the companies which are reporting today on TipRanks earnings calendar.
          What is APLS EPS forecast?
          APLS EPS forecast for the fiscal quarter 2025 (Q4) is -0.37.
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