Strong Topline Growth
Net sales from proprietary products increased 38% year-over-year to $338.1 million in Q1 2026, contributing to total revenues of $392.9 million for the quarter.
Robust Performance Across Key Brands
VIVITROL Q1 net sales of $112.4M (2026 guidance $460M–$480M); ARISTADA Q1 net sales of $93.8M (2026 guidance $365M–$385M); LYBALVI Q1 net sales of $92.4M, up 32% YoY with TRX growth of 21% YoY and 2026 guidance $380M–$400M.
Successful Acquisition and LUMRYZ Launch Momentum
Closed Avadel acquisition mid-February. LUMRYZ recorded approximately $39.5M of net sales in the 6 weeks post-close and ~ $72M for the full quarter reported; exited the quarter with ~3,600 patients on therapy (brand patient count growth ~28% YoY). Full-year LUMRYZ net sales guidance $350M–$370M (Alkermes share $315M–$335M).
Adjusted EBITDA Beat and Improved Near-Term Outlook
Generated adjusted EBITDA of $80.3M in Q1, well above prior Q1 guidance of $30M–$50M; Q2 adjusted EBITDA expected $100M–$120M. Full-year EBITDA outlook improved to positive $105M–$135M after purchase price accounting refinements.
Purchase Price Accounting Refinements Reduced Expected Charges
Inventory step-up expense for LUMRYZ now expected ~$105M in 2026 (vs prior ~$150M), lowering expected 2026 COGS to $320M–$340M (from prior $365M–$385M). Full-year amortization of intangibles revised down to $75M–$85M (from $95M–$105M).
Progressing a Broad Orexin Pipeline
Alixorexton Brilliance Phase III is open for enrollment in NT1 and NT2; Vibrance-2 (NT2) data to be presented in June; Vibrance-3 (IH) Phase II on track to complete in Q4. New molecules ALKS 7290 (ADHD) and ALKS 4510 (fatigue in MS/Parkinson’s) advancing—Phase Ib ADHD data expected Q4 2026 and Phase II (~300 pts) planned for 2026/2027.
Balance Sheet Actions and Share Repurchase
Ended Q1 with ~$538M cash and investments after deploying ~$775M cash toward Avadel acquisition and entering $1.525B term loans due 2031; repurchased ~1M shares for $28M with $172M remaining authorization.