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Aethlon Medical Inc (AEMD)
NASDAQ:AEMD

Aethlon Medical (AEMD) AI Stock Analysis

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AEMD

Aethlon Medical

(NASDAQ:AEMD)

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Neutral 45 (OpenAI - 5.2)
Rating:45Neutral
Price Target:
$2.50
▲(5.04% Upside)
The score is held down primarily by very weak financial performance (minimal/zero recent revenue, large losses, and heavy cash burn). Earnings-call execution on cost reductions and early clinical progress provide some offset, but limited cash and dilution/financing risk (warrants) remain notable. Technicals are mixed with short-term improvement but a still-bearish longer-term trend, and valuation is not supportive due to ongoing losses and no dividend.
Positive Factors
Clinical Progress / Safety
Early clinical safety data from Cohort 1 reduces clinical and regulatory risk over the coming months. Demonstrated tolerance of the 4-hour Hemopurifier treatment supports further cohort expansion and de-risks development pathways, improving prospects for future trials, partnerships, and eventual commercial adoption.
Operating Cost Discipline
A sustained ~48% reduction in operating expenses reflects management’s ability to materially lower cash burn and reallocate scarce resources. If maintained, this structural cost discipline can extend runway, reduce near-term financing frequency, and increase the odds of reaching additional clinical milestones without immediate dilutive capital raises.
Proprietary Technology & Scientific Collaboration
The Hemopurifier’s demonstrated ability to bind disease-related extracellular vesicles, coupled with a UCSF collaboration and planned manuscript, strengthens the company’s scientific credibility. This durable technical differentiation can expand addressable indications (oncology, Long COVID) and underpin longer-term partnerships or licensing opportunities.
Negative Factors
Weak Cash Generation
Trailing cash flow is sharply negative and operating cash flow does not cover losses, creating persistent dependence on external financing. With a reported cash balance near $5.8M, continued cash burn risks truncating development timelines and forces recurring capital raises that can dilute investors and slow program execution.
No Commercial Revenue / Persistent Losses
The company has little-to-no recurring commercial revenue while producing sizable operating and net losses. This structural lack of revenue undermines margin sustainability and makes profitable scaling contingent on successful clinical outcomes or new partnerships, leaving long-term viability tied to uncertain trial results.
Dilution & Financing Dependence
Removing exercise restrictions on pre-funded warrants accelerates potential equity conversion and highlights reliance on financings to fund operations. This structural capital‑raising pathway increases dilution risk for existing shareholders and may pressure governance dynamics and investor returns if repeated before revenue or clinical value is realized.

Aethlon Medical (AEMD) vs. SPDR S&P 500 ETF (SPY)

Aethlon Medical Business Overview & Revenue Model

Company DescriptionAethlon Medical, Inc., a medical technology company, focuses on developing products to diagnose and treat life and organ threatening diseases in the United States. The company develops Aethlon Hemopurifier, a clinical-stage immunotherapeutic device that removes tumor-derived exosomes and life-threatening viruses from the human circulatory system, including removal of COVID-19 virus, associated variants, and related exosomes. Aethlon Medical, Inc. has a collaboration with the University of Pittsburgh Medical Center Hillman Cancer Center for studies related to head and neck cancer. The company was founded in 1999 and is based in San Diego, California.
How the Company Makes MoneyAethlon Medical makes money through the development and commercialization of its Hemopurifier product, targeting both therapeutic and diagnostic markets. Revenue is primarily generated from grants, research and development contracts, and potential sales or licensing of its proprietary technology. As a company focused on early-stage biotechnology, Aethlon also relies on government funding and partnerships with research institutions to support its development efforts. Key factors contributing to its earnings include the expansion of its product applications, regulatory approvals, and strategic collaborations that enhance its market reach and product development pipeline.

Aethlon Medical Earnings Call Summary

Earnings Call Date:Nov 12, 2025
(Q2-2026)
|
% Change Since: |
Next Earnings Date:Feb 16, 2026
Earnings Call Sentiment Neutral
The earnings call highlighted significant progress in clinical trials and substantial reduction in operating expenses, indicating effective cost management. Nonetheless, challenges in patient recruitment for the oncology trial and concerns about cash reserves present potential hurdles. The company's strategic focus on its core projects while managing resources optimally reflects a balanced approach.
Q2-2026 Updates
Positive Updates
Australian Oncology Trial Progress
The ongoing progress in the Australian oncology trial of the Hemopurifier shows promising results. All three participants in Cohort 1 completed a single 4-hour Hemopurifier treatment without any device deficiencies or immediate complications. The trial is advancing to the second cohort with plans for participants to receive two Hemopurifier treatments during a 1-week treatment period.
Financial Expense Reduction
Operating expenses for the quarter ending September 30, 2025, were approximately $1.5 million, down by approximately 48% from $2.9 million in the same period of 2024. This reduction was reflected across payroll, general and administrative expenses, and professional fees.
Preclinical R&D Developments
Aethlon Medical presented preclinical data on Long COVID at the Keystone Symposium, demonstrating the binding of extracellular vesicles from Long COVID patients to the Hemopurifier. The company is preparing a manuscript with UCSF Medical Center collaborators for publication.
Negative Updates
Slow Enrollment in Oncology Trial
Enrollment for Cohort 2 in the Australian oncology trial has been slower than anticipated, attributed to the novel nature of extracorporeal therapies for cancer patients and the complexity of the trial procedures.
Cash Balance Concerns
As of September 30, 2025, Aethlon Medical had a cash balance of approximately $5.8 million, which might raise concerns about the company's ability to sustain operations without additional funding or revenue streams.
Company Guidance
During the Aethlon Medical Second Quarter Fiscal 2026 Earnings Call, the company provided several key updates and metrics regarding its ongoing projects and financial status. Dr. Steven LaRosa shared progress on the Australian oncology trial, highlighting that all three participants in Cohort 1 completed a 4-hour Hemopurifier treatment without adverse events, and the trial is advancing to Cohort 2. The primary endpoint of the trial is safety, with secondary focus on extracellular vesicle (EV) concentration changes. Financially, Aethlon reported a cash balance of approximately $5.8 million as of September 30, 2025, with consolidated operating expenses decreasing by 48% to $1.5 million, down from $2.9 million in the same period of 2024. This reduction was attributed to lower payroll, administrative expenses, and professional fees, resulting in an operating loss decrease to $1.5 million from $2.8 million in the prior year. The company is actively seeking to optimize its resources and accelerate trial enrollment through strategic initiatives.

Aethlon Medical Financial Statement Overview

Summary
Overall fundamentals are very weak: TTM revenue is effectively zero with large operating and net losses, and cash flow shows sustained, heavy burn. The balance sheet is a relative bright spot with modest leverage and positive equity, but ongoing losses and funding needs remain a central risk.
Income Statement
8
Very Negative
Profitability is very weak. In TTM (Trailing-Twelve-Months), revenue is effectively zero while the company is generating large operating losses (EBIT of about -$7.1M and net loss of about -$11.3M). The multi-year pattern shows persistent net losses with no clear path to break-even, and revenue has been volatile and recently absent, which limits visibility into operating leverage and margin recovery.
Balance Sheet
52
Neutral
The balance sheet is a relative bright spot: leverage is modest (TTM debt-to-equity ~0.17) and equity remains positive (~$5.7M) against total assets of ~$7.3M. However, returns are deeply negative (TTM return on equity is negative), reflecting ongoing losses that can pressure the equity base over time if cash burn continues.
Cash Flow
6
Very Negative
Cash generation is very weak with sustained cash burn. TTM (Trailing-Twelve-Months) operating cash flow and free cash flow are both sharply negative, and operating cash flow does not cover reported earnings (coverage is negative). While some prior annual periods show fluctuations in free cash flow growth, the overall profile is consistent with a cash-consuming business that likely depends on external funding.
BreakdownTTMDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue0.000.000.00574.25K294.17K659.10K
Gross Profit-391.72K0.000.00574.25K294.17K659.10K
EBITDA-10.83M-13.04M-12.28M-11.66M-10.30M-7.85M
Net Income-11.26M-13.39M-12.21M-12.03M-10.42M-7.89M
Balance Sheet
Total Assets7.32M7.36M8.25M17.51M19.42M10.67M
Cash, Cash Equivalents and Short-Term Investments5.85M5.50M5.44M14.53M17.07M9.86M
Total Debt496.77K649.75K940.32K1.21M729.41K42.54K
Total Liabilities1.58M2.24M2.48M2.44M2.43M1.38M
Stockholders Equity5.75M5.12M5.77M15.06M17.13M9.43M
Cash Flow
Free Cash Flow-1.72B-7.65M-10.38M-11.45M-10.12M-6.82M
Operating Cash Flow-1.72B-7.65M-10.13M-10.51M-9.77M-6.76M
Investing Cash Flow0.000.00-250.87K-943.11K-349.19K-59.88K
Financing Cash Flow736.11K7.73M1.29M8.91M17.37M7.13M

Aethlon Medical Technical Analysis

Technical Analysis Sentiment
Negative
Last Price2.38
Price Trends
50DMA
3.10
Negative
100DMA
4.64
Negative
200DMA
12.09
Negative
Market Momentum
MACD
-0.16
Positive
RSI
37.78
Neutral
STOCH
2.41
Positive
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For AEMD, the sentiment is Negative. The current price of 2.38 is below the 20-day moving average (MA) of 2.68, below the 50-day MA of 3.10, and below the 200-day MA of 12.09, indicating a bearish trend. The MACD of -0.16 indicates Positive momentum. The RSI at 37.78 is Neutral, neither overbought nor oversold. The STOCH value of 2.41 is Positive, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for AEMD.

Aethlon Medical Risk Analysis

Aethlon Medical disclosed 61 risk factors in its most recent earnings report. Aethlon Medical reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Aethlon Medical Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
46
Neutral
$2.39M-0.02-126.20%97.70%
45
Neutral
$2.34M-0.04-191.39%76.53%
45
Neutral
$2.78M-0.11-178.18%-49.63%82.22%
42
Neutral
$3.14M-0.04-173.74%82.96%82.04%
40
Underperform
$2.80M-0.08-352.39%63.87%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
AEMD
Aethlon Medical
2.33
-53.67
-95.84%
VTAK
Catheter Precision
1.84
-5.38
-74.52%
BJDX
Bluejay Diagnostics
3.19
-10.45
-76.61%
TIVC
Tivic Health Systems
1.03
-3.07
-74.88%
AMIX
Autonomix Medical, Inc.
0.40
-2.29
-85.14%

Aethlon Medical Corporate Events

Private Placements and FinancingRegulatory Filings and Compliance
Aethlon Medical Amends Warrants to Allow Immediate Exercise
Positive
Jan 26, 2026

On January 22, 2026, Aethlon Medical, Inc. and an institutional investor amended a December 5, 2025 Securities Purchase Agreement to remove a requirement that the company obtain shareholder approval under Nasdaq Rule 5635 before pre-funded warrants could be exercised, making those warrants immediately exercisable while leaving all other terms of the agreement unchanged. On the same date, the parties also amended a December 8, 2025 pre-funded common stock purchase warrant on identical terms, a move that accelerates the potential conversion of these instruments into common stock and could impact Aethlon Medical’s capital structure and existing shareholders’ dilution profile.

The most recent analyst rating on (AEMD) stock is a Hold with a $3.00 price target. To see the full list of analyst forecasts on Aethlon Medical stock, see the AEMD Stock Forecast page.

Business Operations and StrategyFinancial DisclosuresRegulatory Filings and Compliance
Aethlon Medical Reports Q2 Financial Results and Progress
Positive
Nov 12, 2025

On November 12, 2025, Aethlon Medical announced its financial results for the fiscal second quarter ending September 30, 2025, reporting a significant reduction in operating expenses by 48% compared to the previous year. The company highlighted its ongoing clinical progress, including recruitment for the second cohort of its Australian oncology trial and collaboration with UCSF on Long COVID research. Aethlon’s Nasdaq compliance issues have been resolved, maintaining its listing, and the company continues to advance its Hemopurifier technology with new evaluations for simplified blood treatment systems.

The most recent analyst rating on (AEMD) stock is a Hold with a $1.50 price target. To see the full list of analyst forecasts on Aethlon Medical stock, see the AEMD Stock Forecast page.

Delistings and Listing ChangesRegulatory Filings and Compliance
Aethlon Medical Regains Nasdaq Compliance After Stock Surge
Positive
Nov 6, 2025

On November 5, 2025, Aethlon Medical, Inc. announced it had regained compliance with the Nasdaq’s minimum bid price requirement, following a period of non-compliance due to its stock price falling below $1.00. This development marks a positive shift for the company, as maintaining its Nasdaq listing is crucial for its market presence and investor confidence.

The most recent analyst rating on (AEMD) stock is a Hold with a $1.50 price target. To see the full list of analyst forecasts on Aethlon Medical stock, see the AEMD Stock Forecast page.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Jan 27, 2026