Completed Cohort 2 and Progressed to Cohort 3 in Australian Oncology Trial
Enrollment and treatment in Cohort 2 completed (3 participants received two 4-hour Hemopurifier treatments each). An independent DSMB identified no safety concerns and recommended advancing to Cohort 3 without protocol modifications. The first participant in Cohort 3 has been treated (three Hemopurifier sessions) with no device deficiencies and is in safety follow-up; screening is active at all three sites.
Clinical Biomarker and Measurement Data Collected
Central lab at the University of Sydney measured extracellular vesicle (EV) and T cell parameters for Cohort 2; formal statistical analyses comparing three dosing regimens will be performed by the CRO at trial completion. Prior cohort data showed reductions in EVs (including PDL1+ EVs) and positive T cell signals.
Preclinical Pipeline Expansion — EV Research in New Indications
Advancing preclinical studies evaluating removal of extracellular vesicles from plasma samples in rheumatoid arthritis and chronic kidney disease (platelet-derived EVs implicated in RA; EVs linked to heart failure in CKD). Work is being conducted in-house and intended to support abstracts and peer-reviewed publications.
Compatibility with Simplified Blood Pump Demonstrated
Initial testing of Hemopurifier compatibility with Sabre Medical’s simplified blood pump showed successful flow rates and fluid transfer. This could enable treatment outside dialysis units, use of less invasive vascular access, and broader physician and site adoption.
Compassionate Use Ebola Protocol Remains Open
The compassionate use protocol for life‑threatening viral infections (Ebola-specific) remains open for enrollment (up to 20 subjects at up to 10 U.S. institutions). Company has shared in vitro and clinical removal data with WHO and U.S. special pathogen centers.
Improved Expense Discipline — Operating Expenses Down 21.9% Year‑over‑Year
Consolidated operating expenses declined 21.9% YoY to approximately $7.3 million in FY2026 from $9.3 million in FY2025, driven by reductions of ~$1.1M in payroll, ~$0.5M in G&A, and ~$0.4M in professional fees.
Stronger Post‑Year‑End Liquidity and Improved Net Loss
Cash and cash equivalents were approximately $5.0 million as of March 31, 2026, and the company raised approximately $1.85 million in net proceeds afterward via an at‑the‑market (ATM) program. Net loss attributable to common stockholders improved to $7.2 million (FY2026) from $13.4 million (FY2025) — a ~46% reduction.
Other Income Improved Versus Prior Year
Other income in FY2026 was approximately $142,000 (primarily interest income) versus other expense of ~ $4 million in FY2025; the prior year included approximately $4.7M of noncash financing-related charges.