Strong ASCENIV Revenue Growth
ASCENIV revenue was $97.5 million in Q1 2026, up approximately 28% year-over-year, with record end-market demand, record new patient starts, growing prescriber adoption, improved product pull-through and patient adherence. Management cites April run-rate in line with Q1 direct sales, indicating continuing momentum into Q2.
Margin Expansion and Gross Profit
Gross profit for the quarter was $80.8 million, resulting in gross margin expansion to 71% from 53% in the prior year period (an increase of ~18 percentage points), reflecting improved mix toward higher-margin ASCENIV and yield-enhanced manufacturing.
Improved Profitability (Adjusted EBITDA and Net Income)
Adjusted EBITDA was $59.7 million, up 24% year-over-year, and adjusted net income rose ~22% year-over-year to $40.7 million. GAAP net income was $45.3 million for the quarter.
Strong Operating Cash Generation and Liquidity
Generated approximately $58 million of cash from operations in Q1 2026 (greater than all of 2025), ended the quarter with $138 million of cash and cash equivalents, received $5 million proceeds from sale of 3 plasma centers, and maintained pro forma net leverage below 0.5x with ~ $100 million of additional borrowing capacity.
Balance Sheet Actions and Capital Return
Company executed accelerated stock repurchases converting ~3.6% of outstanding shares into treasury stock and retains capacity to continue opportunistic share repurchases while supporting growth initiatives.
Operational and Supply Enhancements
Completed monetization of 3 plasma centers while adding a new third-party plasma supplier, established a balanced mix of internal and third-party plasma procurement, and is using yield-enhanced manufacturing for ASCENIV production to maximize high-titer plasma utilization.
Pipeline and Regulatory Catalysts
Received pediatric label expansion approval for ASCENIV and plans pre-IND engagement for SG-001 later in 2026; SG-001 preclinical data to be presented at an upcoming conference and management estimates a potential peak market opportunity of $300M–$500M if approved.