Strong Full-Year Financial Performance
Total revenue of $510,200,000 for FY2025, representing 20% year-over-year growth; adjusted EBITDA of $231,000,000, up 40% YoY; adjusted net income of $160,800,000, up 35% YoY — demonstrating expanding profitability and operating leverage.
Ascentive Product Surge
Ascentive achieved $363,000,000 in net revenue in 2025, a 51% year-over-year increase; company reported a roughly 70/30 split between Ascentive and Bivigam in 2025 and described record utilization and strong prescriber adoption.
Margin Expansion and Yield-Enhanced Production
FY2025 gross margin expanded to 57.4% from 51.5% in 2024 (≈6.0 percentage-point improvement); corporate Q4 2025 gross margin exited at 63.8% (approximately 10% YoY improvement in exit margin). Management attributed margin gains to full integration of yield-enhanced production into commercial operations.
Robust Quarter-End Results
Q4 2025 total revenue of $139,200,000 (up 18% YoY); Q4 adjusted EBITDA of $73,600,000, up 52% YoY; Q4 adjusted net income of $52,600,000, up 57% YoY — indicating accelerating profitability into year-end.
Ambitious and Upward Guidance
2026 guidance: revenue > $635,000,000, adjusted net income > $255,000,000, adjusted EBITDA > $360,000,000. 2027 guidance: revenue > $775,000,000, adjusted EBITDA > $455,000,000. 2029 target: revenue > $1,100,000,000 and adjusted EBITDA > $700,000,000.
Improved Plasma Supply Visibility and Network Repositioning
Strategic repositioning includes monetizing 3 plasma centers while retaining 7 and executing long-term supply agreements; company now has access to over 280 plasma collection centers and improved supply visibility into the late 2030s.
Real-World Evidence and Clinical Validation
Independent peer-reviewed study (Tan et al.) presented/published in 2025 showed statistically significant reductions in infections and hospitalizations for patients who failed prior IVIG and transitioned to Ascentive; 71% of those patients showed clinical improvement, with additional publications expected in 2026.
Leadership and Financial Execution Focus
Planned CFO transition from retiring Brad Tade to incoming Terry Kohler (with expertise in working capital optimization and cash conversion) to support disciplined execution; company reported $88,000,000 in cash at year-end (excluding divestiture proceeds) and expects improving cash generation in 2026.