tiprankstipranks
ADC Therapeutics Ltd (ADCT)
NYSE:ADCT
US Market

ADC Therapeutics (ADCT) Earnings Dates, Call Summary & Reports

412 Followers

Earnings Data

Report Date
May 11, 2026
Before Open (Confirmed)
Period Ending
2026 (Q1)
Consensus EPS Forecast
-0.2
Last Year’s EPS
-0.36
Same Quarter Last Year
Based on 3 Analysts Ratings

Earnings Call Summary

Q4 2025
Earnings Call Date:Mar 10, 2026|
% Change Since:
|
Earnings Call Sentiment|Positive
Overall the call conveyed meaningful progress: encouraging clinical signals from LOTIS-7 and LOTIS-5 lead-in, improved revenues and expense reductions, and a stronger balance sheet with runway into 2028. However, material risks remain — commercial volumes are flat, GAAP losses persist, outcomes depend on upcoming trial readouts and regulatory actions, and the competitive landscape is intensifying. The positives (clinical progress, cost cuts, financing, and clear near-term catalysts) outweigh the negatives, though execution risk remains.
Company Guidance
Management guided that LOTIS‑5 top‑line PFS data will be reported in Q2 2026 (study powered on ~262 events) with full results by year‑end 2026, a potential sBLA/compendia submission in H1 2027 and possible confirmatory approval mid‑2027; LOTIS‑7 full data are planned by end‑2026 and indolent IIT publications between end‑2026 and mid‑2027. They expect multiple 2026 data catalysts, a year‑end cash balance of $261.3M after $100M and $60M PIPE financings and a cash runway at least into 2028. Commercial and financial metrics cited include Q4 2025 net product revenue $22.3M (FY $73.6M), Q4 total operating expense $41.0M (FY $202.9M), adjusted op ex Q4 $39.4M (FY $181.3M; adjusted op ex down 15% Q4 and 6% FY), GAAP net loss Q4 $6.4M ($0.04/sh) and FY $142.6M ($1.12/sh), and an R&D run‑down expected in 2026–2027. They quantified the market opportunity as ~12,000 second‑line and ~6,000 third‑line patients, average cycles increasing ~3→5–6, each 10‑point share ≈ $200M in 2L (≈ $100M in 3L), current ~10% 3L share, and U.S. peak revenue potential of $600M–$1B (LOTIS‑5 ~$200M–$300M; LOTIS‑7 ~$500M–$800M; indolent ~$100M–$200M), citing encouraging signals (LOTIS‑5 safety lead‑in ORR 80%/CR 50%; LOTIS‑7 best ORR 90%/CR 78% in 49 evaluable patients, ≥6‑month follow‑up).
Strong Q4 and Full-Year Net Product Revenue Growth
ZYNLONTA net product revenues were $22.3M in Q4 2025 vs $16.4M in Q4 2024 (approximately +36%) and $73.6M for full-year 2025 vs $69.3M in 2024 (approximately +6.2%), with Q4 strength driven by customer ordering variability and activation of new accounts.
Robust Clinical Data from LOTIS-7 and LOTIS-5 Lead-in
LOTIS-7 Phase Ib updated results showed a 90% best overall response rate and a 78% complete response rate across 49 efficacy-evaluable patients (minimum 6-month follow-up). LOTIS-5 safety lead-in reported an 80% overall response rate and 50% complete response rate, supporting potential competitive second-line efficacy.
Clear Near-Term Development Catalysts and Timelines
Management expects LOTIS-5 top-line PFS data in Q2 2026 (study powered for 262 events) with full results by year-end 2026 and potential sBLA/compendia activity in H1 2027; LOTIS-7 full data and publications are planned by end of 2026, and IIT indolent lymphoma data expected between end-2026 and mid-2027.
Significant Cost Reductions and Improved Operating Efficiency
Company implemented strategic reprioritization and reduced operating cost structure by ~50%. Total adjusted operating expenses were $39.4M in Q4 and $181.3M for full-year 2025, down ~15% (quarter) and ~6% (year) versus prior periods, driven primarily by lower R&D and broad expense reductions.
Improved GAAP Results and Adjustments
GAAP net loss improved to $6.4M in Q4 2025 ($0.04 per share) from $30.7M in Q4 2024, and full-year net loss improved to $142.6M in 2025 from $157.8M in 2024, reflecting catch-up adjustment gains related to the deferred royalty obligation and lower R&D spend.
Strengthened Balance Sheet and Extended Runway
Ended 2025 with $261.3M cash and equivalents (up from $250.9M at year-end 2024, ~+4.1%). Company completed a $100M PIPE in June 2025 and a $60M PIPE in October 2025 and expects cash runway at least into 2028.
Commercial Footprint and Market Position
Established ~10% share in third-line plus DLBCL as a monotherapy; field force covers ~90% of DLBCL potential; management expects incremental commercial and MSL investments prelaunch to support second-line expansion if trials succeed.

ADC Therapeutics (ADCT) Earnings, Revenues Date & History

The upcoming earnings date is based on a company’s previous reporting, and may be updated when the actual date is announced

ADCT Earnings History

Report Date
Fiscal Quarter
Forecast / EPS
Last Year's EPS
EPS YoY Change
Press Release
Slides
Play Transcript
May 11, 2026
2026 (Q1)
-0.20 / -
-0.36
Mar 10, 2026
2025 (Q4)
-0.27 / -0.04
-0.2986.21% (+0.25)
Nov 10, 2025
2025 (Q3)
-0.36 / -0.30
-0.4228.57% (+0.12)
Aug 12, 2025
2025 (Q2)
-0.49 / -0.50
-0.38-31.58% (-0.12)
May 14, 2025
2025 (Q1)
-0.40 / -0.36
-0.5635.71% (+0.20)
Mar 27, 2025
2024 (Q4)
-0.41 / -0.29
-1.0371.84% (+0.74)
Nov 07, 2024
2024 (Q3)
-0.40 / -0.42
-0.5827.59% (+0.16)
Aug 06, 2024
2024 (Q2)
-0.46 / -0.38
-0.5834.48% (+0.20)
May 06, 2024
2024 (Q1)
-0.56 / -0.56
-0.7424.32% (+0.18)
Mar 13, 2024
2023 (Q4)
-0.50 / -1.03
-0.3-243.33% (-0.73)
The table shows recent earnings report dates and whether the forecast was beat or missed. See the change in forecast and EPS from the previous year.
Beat
Missed

ADCT Earnings-Related Price Changes

Report Date
Price 1 Day Before
Price 1 Day After
Percentage Change
Mar 10, 2026
$4.23$4.80+13.48%
Nov 10, 2025
$4.04$4.21+4.21%
Aug 12, 2025
$2.68$2.94+9.70%
May 14, 2025
$1.32$1.81+37.12%
Earnings announcements can affect a stock’s price. This table shows the stock's price the day before and the day after recent earnings reports, including the percentage change.

FAQ

When does ADC Therapeutics Ltd (ADCT) report earnings?
ADC Therapeutics Ltd (ADCT) is schdueled to report earning on May 11, 2026, Before Open (Confirmed).
    What is ADC Therapeutics Ltd (ADCT) earnings time?
    ADC Therapeutics Ltd (ADCT) earnings time is at May 11, 2026, Before Open (Confirmed).
      Where can I see when companies are reporting earnings?
      You can see which companies are reporting today on our designated earnings calendar.
        What companies are reporting earnings today?
        You can see a list of the companies which are reporting today on TipRanks earnings calendar.
          What is ADCT EPS forecast?
          ADCT EPS forecast for the fiscal quarter 2026 (Q1) is -0.2.