Record Annual Revenue and Strong Growth
Worldwide revenue for 2025 was $200.9 million, a 20.2% year-over-year increase, with fourth quarter revenue of $56.3 million up 15%.
Robust U.S. Adoption and Procedure Growth
U.S. revenue grew 20.6% for the year to $191.1 million driven by a 22% increase in procedure volume; Q4 U.S. revenue was $53.5 million, up 13.9%, and U.S. 2-year stack revenue grew 20.7% (90 bps acceleration vs. Q3).
Expanding Physician Base and Commercial Productivity
Record 1,640 physicians performed procedures in Q4 (addition of 250 physicians, +18% YoY). Over 1,640 active physicians in Q4 and >2,400 U.S. physicians performing nearly 22,000 procedures in 2025. Annual revenue per territory was $2.1 million, +18% YoY, and 13th consecutive quarter of double-digit territory productivity growth.
First Full Year Positive Adjusted EBITDA and Margin Improvement
Delivered positive adjusted EBITDA of $8.9 million for full year 2025 (versus a $5.1 million adjusted EBITDA loss in 2024), a roughly $14 million year-over-year improvement. Q4 adjusted EBITDA was $5.1 million, a 176.2% improvement with a 9.1% adjusted EBITDA margin.
Improved Profitability and Narrowing Net Loss
Q4 net loss narrowed to $1.6 million ($0.04 per diluted share) versus $4.5 million prior-year quarter. Full-year net loss narrowed 38.8% to $18.9 million ($0.44 per diluted share).
Positive Free Cash Flow and Strong Liquidity
Exited 2025 with $147.8 million cash and equivalents (up $2.1 million from Q3). Generated positive free cash flow in Q4 of ~ $0.5 million and full-year cash consumption improved to $2.2 million from $16 million in 2024.
Significant Reimbursement and Regulatory Wins
Secured NTAP for iFuse TORQ TNT and TPT for iFuse Bedrock Granite; Medicare OBL reimbursement for INTRA X increased by 17% effective Jan 1, 2026. Granite benefits from TPT with a $0 device offset (100% facility-reported cost reimbursement).
Product Innovation and Pipeline Momentum
Launched INTRA Ti (alpha launch) and expect commercialization of a third breakthrough device in late 2026 (510(k) filing targeted in Q3). iFuse Bedrock Granite outpaced deformity market growth; iFuse TORQ TNT saw a 50% increase in physician adoption in Q4.
Strategic Commercial Partnership
Entered a strategic partnership with Smith & Nephew to expand trauma reach into Level 1 and Level 2 trauma centers, accelerating penetration of TORQ/TNT and freeing direct sales to focus on spine and interventional markets.
Guidance Showing Continued Growth
2026 revenue guidance of $228.5M to $232.5M implying 14% to 16% YoY growth, with expected gross margin approximately 78% and OpEx growth ~12.5%; company expects increased adjusted EBITDA and continued progress toward free cash flow goals.