Rhythm Pharmaceuticals demonstrated strong revenue growth and regulatory progress, particularly for IMCIVREE in hypothalamic obesity. While international revenue faced challenges, the company's successful equity offering and promising data in BBS highlight a positive outlook. R&D costs are rising, but the overall sentiment remains optimistic.
Company Guidance
During the Rhythm Pharmaceuticals Q3 2025 earnings call, the company provided comprehensive guidance on various metrics and strategic initiatives. Rhythm reported $51.3 million in global IMCIVREE sales for the quarter, marking a 6% sequential growth, driven by a 10% increase in the number of patients on reimbursed therapy. The U.S. contributed $38.2 million to this revenue with an 84% gross-to-net ratio. Internationally, revenue was $13.1 million, though impacted by a $3.2 million one-time charge due to reimbursement agreements in France. The company highlighted its robust balance sheet, bolstered by a $189 million equity offering in July, ensuring at least 24 months of operational runway. Rhythm is preparing for the potential U.S. launch of IMCIVREE in acquired hypothalamic obesity, with a PDUFA date set for December 20, 2025, and a European launch anticipated in the second half of 2026. The company also plans to report preliminary results from its Phase II trial in Prader-Willi syndrome by year-end, with a target for a 5% BMI decrease at 52 weeks in the Phase III trial.
Strong Revenue Growth
Rhythm Pharmaceuticals reported Q3 2025 revenue of $51.3 million, a 6% sequential increase from Q2 2025. The U.S. accounted for $38.2 million (74%) and international sales contributed $13.1 million (26%).
Successful Equity Offering
The company strengthened its balance sheet with a $189 million equity offering in July 2025.
Regulatory Progress for IMCIVREE
IMCIVREE's regulatory filings for acquired hypothalamic obesity were accepted by both the FDA and EMEA, with a PDUFA date set for December 20, 2025.
Promising Data in Bardet-Biedl Syndrome
A German study showed that 80% of patients with BBS experienced improvement in steatotic liver disease or stabilization at the lowest grade after 6 months of setmelanotide therapy.
Rhythm Pharmaceuticals (RYTM) Earnings, Revenues Date & History
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The table shows recent earnings report dates and whether the forecast was beat or missed. See the change in forecast and EPS from the previous year.
Beat
Missed
RYTM Earnings-Related Price Changes
Report Date
Price 1 Day Before
Price 1 Day After
Percentage Change
Nov 04, 2025
$113.74
$104.99
-7.69%
Aug 05, 2025
$90.24
$88.57
-1.85%
May 07, 2025
$62.71
$64.63
+3.06%
Feb 26, 2025
$51.03
$53.32
+4.49%
Earnings announcements can affect a stock’s price. This table shows the stock's price the day before and the day after recent earnings reports, including the percentage change.
FAQ
When does Rhythm Pharmaceuticals Inc (RYTM) report earnings?
Rhythm Pharmaceuticals Inc (RYTM) is schdueled to report earning on Mar 04, 2026, TBA (Confirmed).
What is Rhythm Pharmaceuticals Inc (RYTM) earnings time?
Rhythm Pharmaceuticals Inc (RYTM) earnings time is at Mar 04, 2026, TBA (Confirmed).
Where can I see when companies are reporting earnings?
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