Strong Top-Line Growth
Royalty receipts grew 13% for the full year and 17% in Q4; portfolio receipts (including milestones) grew 16% for the year and 18% in Q4, outperforming initial guidance and prompting three guidance raises during 2025.
Attractive Returns Metrics
Return on invested capital was 15.8% and return on invested equity was 22.8% for 2025, supported by a sale of MorphoSys development bonds that generated ~$511M proceeds and ~25% IRR on that investment.
Material Capital Deployment and Shareholder Returns
Announced transaction value totaled $4.7B in 2025; deployed capital was $2.6B for the year (including $887M in Q4). Returned $1.7B to shareholders via $1.2B in share repurchases (37M shares) and >$500M in dividends; weighted average share count declined ~5%.
Internalization Delivered Cost Savings
Manager internalization completed in May 2025 drove operating/professional costs down to 6.7% of portfolio receipts in Q4 (8.9% for the year). Company expects 2026 operating/professional costs of 5%–6.5% of portfolio receipts and $100M of run-rate savings in 2026.
Synthetic Royalties Momentum
2025 was the strongest year ever for synthetic royalty transactions: four synthetic deals totaling >$2B and the market value for synthetics jumped ~50% year-over-year to ~$4.7B; synthetic announced value exceeded existing royalties in committed capital for the first time.
Robust Portfolio and Pipeline Potential
Portfolio includes 20 development-stage therapies with combined non-risk-adjusted peak sales >$43B, which the company estimates could translate into >$2.1B in peak annual royalties; multiple pivotal readouts expected over the next 24 months.
Strong Cash Generation and Liquidity
Portfolio cash flow (adjusted EBITDA less net interest) was $815M in Q4 and $2.7B for the year; cash and equivalents totaled $619M, and the company has access to >$3.5B of financial capacity (including $9.2B investment-grade debt and an undrawn $1.8B revolver).
Dividend Increase and Capital Return Discipline
Dividend was increased by 7% for 2026 consistent with mid-single-digit growth target; management emphasized a dynamic capital allocation framework balancing buybacks, dividends, and royalty investments.