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Krystal Biotech (KRYS)
NASDAQ:KRYS
US Market
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Krystal Biotech (KRYS) Earnings Dates, Call Summary & Reports

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Earnings Data

Report Date
Aug 10, 2026
Before Open (Confirmed)
Period Ending
2026 (Q2)
Consensus EPS Forecast
1.79
Last Year’s EPS
1.29
Same Quarter Last Year
Based on 11 Analysts Ratings

Earnings Call Summary

Q1 2026
Earnings Call Date:May 04, 2026|
% Change Since:
|
Earnings Call Sentiment|Positive
The call emphasized strong commercial momentum, robust profitability, a growing international launch and a busy clinical pipeline with multiple near-term readouts and regulatory designations — balanced by operational challenges including insurance switchovers, start-stop treatment dynamics, rising G&A, certain program-specific regulatory/timing requirements, and ongoing European pricing negotiations. Overall the positives (revenue growth, high gross margin, strong cash position, multiple upcoming data readouts and regulatory designations) materially outweigh the operational and timing headwinds described.
Company Guidance
Krystal reiterated guidance for 2026 non‑GAAP R&D and SG&A of approximately $175 million to $195 million and highlighted a busy clinical and commercial year: Q1 net revenue was $116.4 million (U.S. $87.5M; Europe + Japan $28.9M), up 9% sequentially vs. 4Q25 and 32% year‑over‑year vs. Q1 2025, bringing cumulative VYJUVEK revenue to >$846M; gross margin was 95% (COGS $6.3M), R&D expense $15.3M, G&A $41.0M, noncash stock‑comp $13.6M, net income $55.9M (EPS $1.91 basic / $1.83 diluted), and cash & investments exceed $1 billion. Management expects two registrational readouts this year (and two more in 2027), up to six potential data readouts before year‑end (including KB803 with enrollment complete at 16 patients and a Q4 readout; KB801 ~60‑patient readout later this year; KB807/KB111 repeat‑dose readouts later this year; KB407 5‑patient 24‑week repeat‑dose dosing starting this month with data by year‑end), regulatory milestones (Germany decision H2 2026; France in 2027; potential Italy/Spain launches in H2 2026 pending negotiations), and commercial traction (U.S. 695 reimbursement approvals, >60 new prescribers in Q1 and 570 unique prescribers since launch; >140 DDEB patients prescribed in Germany/Japan/France), with management noting roughly 60% market share among ~1,200 identified patients.
Strong Quarter Revenue and Growth
Global net revenue for VYJUVEK was $116.4 million in Q1 2026, representing 9% sequential growth versus Q4 2025 and a 32% increase versus Q1 2025; cumulative net VYJUVEK revenue since launch exceeded $846 million.
High Profitability and Earnings
Krystal delivered its 11th consecutive quarter of positive EPS with net income of $55.9 million in Q1 2026 (basic EPS $1.91, diluted $1.83) versus $35.7 million (basic $1.24, diluted $1.20) in Q1 2025 — net income increased ~56.6% year-over-year.
Very Strong Gross Margin and Cash Position
Gross margin was 95% in Q1 2026 (up from 94% in Q1 2025) driven by manufacturing process improvements; combined cash and investments exceeded $1 billion, supporting pipeline and commercial expansion.
International Launch Traction
Europe + Japan contributed $28.9 million in net revenue (≈24.8% of the quarter's revenue). More than 140 DDEB patients have been prescribed VYJUVEK across Germany, Japan and France; company expects potential launches in Italy and Spain in H2 2026 pending negotiations.
U.S. Commercial Momentum and Access
U.S. net revenue was $87.5 million for the quarter, with over 695 reimbursement approvals and 570 unique prescribers since launch (60 new prescribers in Q1), indicating expanding prescriber base and patient access.
Robust Clinical Pipeline and Upcoming Readouts
Company positioned for multiple data readouts: completed enrollment in KB803 (16 patients) with anticipated Q4 2026 readout; KB801 registrational study on track for later this year; up to six potential readouts before year-end including two registrational readouts and updates for KB707 and KB408.
Regulatory/Platform Advantage
FDA granted platform technology designations to KB407 (CF) and KB111 (Hailey-Hailey) in addition to prior designation for KB801, which company says streamlines interactions with FDA and provides compounding regulatory advantages across programs.
Controlled Cost Guidance and Non-GAAP Outlook
Noncash stock-based compensation was stable (~$13.6 million). Management reaffirmed prior guidance for non-GAAP R&D and SG&A of approximately $175 million to $195 million for full-year 2026.

Krystal Biotech (KRYS) Earnings, Revenues Date & History

The upcoming earnings date is based on a company’s previous reporting, and may be updated when the actual date is announced

KRYS Earnings History

Report Date
Fiscal Quarter
Forecast / EPS
Last Year's EPS
EPS YoY Change
Press Release
Slides
Play Transcript
Aug 10, 2026
2026 (Q2)
1.79 / -
1.29
May 04, 2026
2026 (Q1)
1.49 / 1.83
1.252.50% (+0.63)
Feb 17, 2026
2025 (Q4)
1.53 / 1.70
1.5211.84% (+0.18)
Nov 03, 2025
2025 (Q3)
1.09 / 2.66
0.91192.31% (+1.75)
Aug 04, 2025
2025 (Q2)
1.19 / 1.29
0.53143.40% (+0.76)
May 06, 2025
2025 (Q1)
1.43 / 1.20
0.033900.00% (+1.17)
Feb 19, 2025
2024 (Q4)
1.18 / 1.52
0.3406.67% (+1.22)
Nov 04, 2024
2024 (Q3)
0.99 / 0.91
2.79-67.38% (-1.88)
Aug 05, 2024
2024 (Q2)
0.73 / 0.53
-1.25142.40% (+1.78)
May 06, 2024
2024 (Q1)
0.27 / 0.03
-1.76101.70% (+1.79)
The table shows recent earnings report dates and whether the forecast was beat or missed. See the change in forecast and EPS from the previous year.
Beat
Missed

KRYS Earnings-Related Price Changes

Report Date
Price 1 Day Before
Price 1 Day After
Percentage Change
May 04, 2026
$266.04$286.95+7.86%
Feb 17, 2026
$276.45$287.84+4.12%
Nov 03, 2025
$197.51$197.85+0.17%
Aug 04, 2025
$156.98$134.94-14.04%
Earnings announcements can affect a stock’s price. This table shows the stock's price the day before and the day after recent earnings reports, including the percentage change.

FAQ

When does Krystal Biotech (KRYS) report earnings?
Krystal Biotech (KRYS) is schdueled to report earning on Aug 10, 2026, Before Open (Confirmed).
    What is Krystal Biotech (KRYS) earnings time?
    Krystal Biotech (KRYS) earnings time is at Aug 10, 2026, Before Open (Confirmed).
      Where can I see when companies are reporting earnings?
      You can see which companies are reporting today on our designated earnings calendar.
        What companies are reporting earnings today?
        You can see a list of the companies which are reporting today on TipRanks earnings calendar.
          What is KRYS EPS forecast?
          KRYS EPS forecast for the fiscal quarter 2026 (Q2) is 1.79.