Strong Revenue Performance
Jazz Pharmaceuticals generated over $1 billion in total revenue in Q2 2025, with neuroscience assets leading the growth. Xywav grew 13% year-over-year, with robust net patient additions in both narcolepsy and idiopathic hypersomnia.
Strategic Pipeline Developments
Jazz is preparing for the anticipated approval of dordaviprone with an upcoming FDA PDUFA target action date of August 18. This could enhance Jazz's presence in rare oncology.
Oncology Pipeline Advancements
Positive Phase III data for Zepzelca presented at ASCO and the addition of a new Phase II trial for zanidatamab in HER2-positive breast cancer highlight progress in Jazz's R&D pipeline.
Financial Guidance and Cash Flow
Despite a modest reduction in revenue guidance, Jazz has raised the lower end of its ANI and EPS guidance for 2025, supported by reductions in SG&A, R&D, and effective tax rate guidance.