Crinetics Pharmaceuticals Receives Buy Rating on Promising Phase 2 Trial Results and Strong Financial PositionThis morning, Crinecs Pharmaceuc als (Nasdaq: CRNX) reported top- line Phase 2 open-label data with its once-daily oral ACTH-receptor antagonist, atumelnant, in adults with congenital adrenal hyperplasia (CAH). Recall that prior to the December 2024 approval of Neurocrine’s (Nasdaq: NBIX) twice-daily CRF1-r antagonist, Crenessity (crinecerfont), there were no available treatments for CAH beyond high-dose glucocorc oids (GCs). In CAH, long-term exposure to supraphysiological levels GCs is associated with harmful consequences ranging from metabolic disease, loss of bone density, and psychological disturbances.