Revenue Growth and Top-Line Metrics
Total net revenue rose to $45.1 million in Q1 2026 from $42.0 million in Q1 2025, an increase of approximately 7.4% year-over-year. U.S. revenue was broadly consistent with Q1 2025. The overall IPE market grew ~3% YoY in Q1 2026.
U.S. Market Share and Branded Prescription Growth
Amarin's share of the IPE market increased to 48% at March 31, 2026 from 42% a year earlier (+6 percentage points). VASCEPA branded prescriptions rose 17% in Q1 2026 versus Q1 2025, demonstrating continued branded demand despite generic competition.
European Partnership Traction (Recordati)
Under the Recordati partnership, Q1 2026 European product revenue was $4.9 million and more than doubled (+113%) versus Q4 2025 ($2.3 million), driven by $3.0 million of supply shipments to Recordati in Q1. Recordati has commenced sales of VAZKEPA in 10 countries; Europe IP protection extends through 2039 across 59 countries.
Global Commercial Expansion and Pipeline Filings
Continued rest-of-world growth with partners in China, Australia, Canada and the Middle East (Q1 2026 RoW revenue $2.8 million vs none in Q1 2025). Preparing for early-2027 launches in South Korea and Singapore; regulatory reviews in Thailand and the Philippines; Vietnam filing submitted in Q1 2026 and Malaysia planned for Q2 2026.
Operating Expense Reductions and Restructuring Progress
Total operating expenses declined 31% YoY ($12.8 million) to $29.1 million in Q1 2026. Excluding a $3.3 million restructuring charge, operating expenses were $25.8 million, a 38% YoY reduction. SG&A declined 42% YoY and represented 47% of net sales in Q1 2026 versus 87% in Q1 2025. Company expects ~$70 million in total operating expense savings by June 30, 2026.
Improved Profitability and Cash Generation
Operating loss narrowed to $11.3 million in Q1 2026 from $16.8 million in Q1 2025; excluding restructuring charges, operating loss was $8.0 million. Generated positive operating cash flow of $6.4 million in Q1 2026 (second consecutive quarter). Company ended the quarter with $308 million in cash and investments (up from $303 million at year-end 2025), no debt, and working capital of $450 million, and expects to be cash-flow positive for full-year 2026.
Favorable Clinical and Guideline Developments
Updated ACC/AHA 2026 lipid management guideline positions icosapent ethyl (VASCEPA) as the only primary triglyceride-lowering medication shown to reduce cardiovascular event risk on top of statin therapy. Company cites >500 peer-reviewed publications and >30 million prescriptions by >250,000 HCPs supporting the therapy's evidence base.