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ZyVersa Therapeutics (ZVSA)
OTHER OTC:ZVSA
US Market

ZyVersa Therapeutics (ZVSA) AI Stock Analysis

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ZVSA

ZyVersa Therapeutics

(OTC:ZVSA)

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Neutral 46 (OpenAI - 5.2)
Rating:46Neutral
Price Target:
$0.22
▲(72.31% Upside)
The score is primarily constrained by very weak financial performance: immaterial revenue, extremely large losses, heavy negative free cash flow, and negative equity. Technicals provide some offset via short-term momentum (price above 20/50/100-day averages with positive MACD), but elevated RSI/Stoch suggests the move is stretched, and valuation remains unattractive due to negative earnings and no indicated dividend yield.
Positive Factors
Low reported leverage
Very low reported debt reduces ongoing interest burdens and preserves borrowing headroom, improving the company’s structural ability to fund clinical programs or negotiate partnerships. Over months this lowers solvency pressure versus highly levered peers when raising capital.
Focused clinical-stage pipeline
A concentrated pipeline in renal and inflammatory indications creates durable strategic focus and technical expertise. Specialized assets (mAb and small-molecule platforms) increase odds of partnering or milestone financing, which can materially de-risk funding needs over a multi-month horizon.
Small positive TTM gross profit
A modest positive gross profit suggests the company can, at least in part, generate margin on product-related activity or recognize revenue with controllable direct costs. If scaled, this structural cost profile could support better long-term unit economics once commercialized.
Negative Factors
Minimal revenue base
Essentially no recurring revenue leaves the business dependent on external financing and makes commercial viability unproven. Over 2-6 months this impairs self-funding of trials, increases dilution risk, and limits operational runway absent new capital or strategic transactions.
Deep cash burn and negative cash flow
Sustained, worsening negative operating and free cash flow creates a structural funding gap that must be filled via equity or partnerships. Persistent cash burn undermines long-term R&D continuity and elevates refinancing risk, pressuring strategic options over months.
Negative equity and diminished capital base
Negative equity indicates capital erosion and reduces financial flexibility: borrowing capacity, counterparty confidence, and partner negotiating leverage are all impaired. Structurally this raises insolvency risk and complicates long-term funding of clinical programs.

ZyVersa Therapeutics (ZVSA) vs. SPDR S&P 500 ETF (SPY)

ZyVersa Therapeutics Business Overview & Revenue Model

Company DescriptionZyVersa Therapeutics, Inc., a clinical stage biopharmaceutical company, develops and commercializes products for the treatment of renal and inflammatory diseases. It engages in the development of VAR 200, a cholesterol efflux mediator to treat focal segmental glomerulosclerosis, alport syndrome, and diabetic kidney disease; and IC 100, a novel inflammasome ASC inhibitor for treatment of multitude of inflammatory diseases. ZyVersa Therapeutics, Inc. is headquartered in Weston, Florida.
How the Company Makes MoneyZyVersa Therapeutics makes money primarily through the development and commercialization of its drug candidates. Revenue streams include potential milestone payments and royalties from licensing agreements with pharmaceutical partners. The company may also generate income from collaborations and partnerships aimed at advancing its drug candidates through clinical trials and towards market approval. Additionally, ZyVersa could explore strategic alliances to leverage shared resources and expertise, contributing to its financial growth.

ZyVersa Therapeutics Financial Statement Overview

Summary
Income statement shows immaterial TTM revenue (~$26K) with extremely large operating/net losses and highly negative margins. Cash flow is deeply negative with worsening free cash flow, implying heavy cash burn and financing dependence. Balance sheet has low/near-zero debt, but negative equity in TTM signals significant strain and reduced financial flexibility.
Income Statement
3
Very Negative
TTM (Trailing-Twelve-Months) revenue is immaterial (~$26K) and profitability is deeply negative, with extremely large operating and net losses and highly negative margins. Annual periods also show no meaningful revenue generation, indicating the business remains pre-commercial and heavily loss-making. Strength is limited to a small positive gross profit in TTM, but it is not enough to offset the large expense base and persistent losses.
Balance Sheet
10
Very Negative
Leverage is low on paper (total debt reported at or near zero in recent periods), which is a positive. However, equity has turned negative in TTM, signaling balance-sheet strain and reducing financial flexibility; assets are also very small in TTM versus prior years, pointing to a significantly diminished capital base. Earlier years showed positive equity, but the trajectory deteriorates sharply into the most recent period.
Cash Flow
6
Very Negative
Cash generation is consistently negative, with TTM (Trailing-Twelve-Months) operating and free cash flow both deeply negative and worsening versus the prior period (free cash flow growth is strongly negative). While free cash flow broadly tracks net losses (suggesting losses are largely cash-based rather than accounting-only), the magnitude of cash burn implies ongoing financing dependence and elevated runway/refinancing risk.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue26.08K0.000.000.000.000.00
Gross Profit13.04K-6.93K-10.40K-10.40K-10.40K-10.40K
EBITDA-20.76B-9.14B-107.74M-14.43M-7.25M-12.16M
Net Income-19.81B-9.41B-98.30M-14.05M-8.08M-12.68M
Balance Sheet
Total Assets1.04M20.60M22.11M118.51M1.13M685.57K
Cash, Cash Equivalents and Short-Term Investments527.98K1.53M3.14M5.90M328.58K174.67K
Total Debt0.000.008.66K108.76K9.15M3.82M
Total Liabilities12.77M12.08M11.04M18.51M13.63M9.24M
Stockholders Equity-11.73M8.52M11.07M99.99M-12.50M-8.56M
Cash Flow
Free Cash Flow-4.70B-7.56M-8.72M-1.49M-5.08M-5.11M
Operating Cash Flow-4.70B-7.56M-8.72M-4.89M-5.08M-5.11M
Investing Cash Flow0.000.000.000.000.000.00
Financing Cash Flow3.70B5.95M5.96M1.87M5.23M4.56M

ZyVersa Therapeutics Technical Analysis

Technical Analysis Sentiment
Neutral
Last Price0.13
Price Trends
50DMA
0.15
Positive
100DMA
0.15
Positive
200DMA
0.32
Negative
Market Momentum
MACD
0.01
Negative
RSI
54.01
Neutral
STOCH
26.01
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For ZVSA, the sentiment is Neutral. The current price of 0.13 is below the 20-day moving average (MA) of 0.16, below the 50-day MA of 0.15, and below the 200-day MA of 0.32, indicating a neutral trend. The MACD of 0.01 indicates Negative momentum. The RSI at 54.01 is Neutral, neither overbought nor oversold. The STOCH value of 26.01 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Neutral sentiment for ZVSA.

ZyVersa Therapeutics Risk Analysis

ZyVersa Therapeutics disclosed 86 risk factors in its most recent earnings report. ZyVersa Therapeutics reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

ZyVersa Therapeutics Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
46
Neutral
$1.60M-0.0488.30%
43
Neutral
$738.01K-0.07178.82%-4121.10%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
ZVSA
ZyVersa Therapeutics
0.18
-1.33
-88.15%
SCNI
Scinai Immunotherapeutics
0.82
-2.72
-76.85%
ADTX
Aditxt
1.17
-3,154.36
-99.96%
CERO
CERo Therapeutics Holdings
0.05
-46.95
-99.90%
PBM
Psyence Biomedical
0.67
-12.96
-95.08%
CDT
Conduit Pharmaceuticals
1.40
-598.60
-99.77%
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Jan 13, 2026