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Syros Pharmaceuticals (SYRS)
OTHER OTC:SYRS
Sy-2101, Arsenic Trioxide
Acute Promyelocytic Leukemia
Phase I
Suspended
A Study for Oral SY-2101 for Participants With Acute Promyelocytic Leukemia
Aug 03, 2021
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Venetoclax, Azacitidine, Tamibarotene
Acute Myeloid Leukemia
Phase II
Terminated
Tamibarotene Plus Venetoclax/Azacitidine in Participants With Newly Diagnosed Acute Myeloid Leukemia (AML)
May 24, 2021
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Azacitidine, Tamibarotene
Myelodysplastic Syndromes
Phase III
Terminated
Tamibarotene Plus Azacitidine in Participants With Newly Diagnosed RARA-positive Higher-Risk Myelodysplastic Syndrome
Mar 11, 2021
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Gemcitabine, Nab-paclitaxel, Fulvestrant, Sy-5609
Small-cell Lung Cancer, Breast Cancer, Pancreatic Cancer, Advanced Solid Tumor
Phase I
Completed
A Study of SY 5609, a Selective CDK7 Inhibitor, in Advanced Solid Tumors
Jan 22, 2020
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Carboplatin, Fulvestrant, Sy-1365 (Part 1), Sy-1365 (Cohort 2), Sy-1365 (Cohort 5), Sy-1365 (Part 2 Single Agent)
Ovarian Cancer, Breast Cancer, Advanced Solid Tumors
Phase I
Terminated
A Study of SY-1365 in Adult Patients With Advanced Solid Tumors
Apr 19, 2017
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Daratumumab, Azacitidine, Tamibarotene
Acute Myeloid Leukemia, Myelodysplastic Syndrome
Phase II
Completed
A Biomarker-Directed Phase 2 Trial of Tamibarotene (SY-1425) in Participants With Acute Myeloid Leukemia or Myelodysplastic Syndrome
Jun 13, 2016
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FAQ
What are the FDA phases for drug approval?
The FDA approval process for new drugs is divided into several phases:
a. Preclinical testing
b. Phase 1 – Safety and dosage
c. Phase 2 – Effectiveness and side effects
d. Phase 3 – Confirmation of effectiveness, monitoring of adverse reactions, and comparison with existing treatments
e. Phase 4 – Post-marketing studies to track long-term safety and effectiveness
a. Preclinical testing
b. Phase 1 – Safety and dosage
c. Phase 2 – Effectiveness and side effects
d. Phase 3 – Confirmation of effectiveness, monitoring of adverse reactions, and comparison with existing treatments
e. Phase 4 – Post-marketing studies to track long-term safety and effectiveness
What is a clinical trial?
A clinical trial is a carefully designed study in which researchers test a drug, treatment, or medical device in people to evaluate its safety, effectiveness, and potential side effects. These trials are essential for determining whether a new treatment should be approved for widespread use.
What drugs does Syros Pharmaceuticals (SYRS) have in its pipeline
SYRS is currently developing the following drugs: Sy-2101, Arsenic Trioxide, Venetoclax, Azacitidine, Tamibarotene, Azacitidine, Tamibarotene. These drug candidates are in various stages of clinical development as the company works toward FDA approval.