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Spruce Biosciences, Inc. (SPRB)
OTHER OTC:SPRB
US Market
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Spruce Biosciences (SPRB) Stock Forecast & Price Target

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SPRB Financial Forecast

SPRB Earnings Forecast

Currently, no earnings data available.
Currently, no earnings data available.

SPRB Sales Forecast

Currently, no sales data available.
Currently, no sales data available.

Detailed List of Analyst Forecasts​

Detailed List of Analyst Forecasts​
Analyst Profile
Expert Firm
Price Target
Position
Upside / Downside
Action
Date
Follow
Article
Leerink Partners Analyst forecast on SPRB
Leerink Partners
Leerink Partners
$1
Hold
-89.98%
Downside
Reiterated
05/07/25
Analysts Offer Insights on Healthcare Companies: Adicet Bio (NASDAQ: ACET) and Spruce Biosciences (Other OTC: SPRB)We are updating our model to reflect SPRB's 1Q25 financial results and corporate update; the BLA for tralesinidase alfa for the treatment of Sanfilippo Syndrome Type B (MPS IIIB) remains on track for 1H26. Following the strategy update last month (Pipeline but MP), SPRB is focused on advancing tralesinidase alfa, an enzyme replacement therapy (ERT), for the treatment of MPS IIIB. the FDA confirmed in a Type C meeting that HS-NRE (heparan sulfate non-reducing end) is deemed to be a surrogate biomarker reasonably likely to predict clinical benefit and could serve as a basis for Accelerated Approval. The company continues to guide to a Biologics License Application (BLA) submission in the first half of 2026.
RBC Capital Analyst forecast on SPRB
RBC Capital
RBC Capital
$0.5
Hold
-94.99%
Downside
Reiterated
05/06/25
Analysts Conflicted on These Healthcare Names: Spruce Biosciences (Other OTC: SPRB), Cigna (NYSE: CI) and Axsome Therapeutics (NASDAQ: AXSM)
H.C. Wainwright Analyst forecast on SPRB
H.C. Wainwright
H.C. Wainwright
Hold
Reiterated
04/28/25
Spruce Biosciences: Promising Strategy Amidst Financial Challenges and Regulatory Uncertainties
Citizens JMP Analyst forecast on SPRB
Citizens JMP
Citizens JMP
Hold
Reiterated
04/23/25
Citizens JMP reiterates Market Perform Rating on Spruce Biosciences, Inc. (SPRB)Citizens JMP analyst Jonathan Wolleben reiterated a Market Perform rating and {REMOVEPT} price target on Spruce Biosciences, Inc. (NASDAQ: SPRB).
Oppenheimer Analyst forecast on SPRB
Oppenheimer
Oppenheimer
Hold
Downgraded
12/11/24
Spruce Biosciences Downgraded to Hold Amid Unmet Clinical Trial Endpoints and Strategic Reevaluation
Ranks
Any
Any
Analyst Rating
Any
Any
Upside/ Downside
Any
Any
Action
Any
Any
Analyst Profile
Expert Firm
Price Target
Position
Upside / Downside
Action
Date
Follow
Article
Leerink Partners Analyst forecast on SPRB
Leerink Partners
Leerink Partners
$1
Hold
-89.98%
Downside
Reiterated
05/07/25
Analysts Offer Insights on Healthcare Companies: Adicet Bio (NASDAQ: ACET) and Spruce Biosciences (Other OTC: SPRB)We are updating our model to reflect SPRB's 1Q25 financial results and corporate update; the BLA for tralesinidase alfa for the treatment of Sanfilippo Syndrome Type B (MPS IIIB) remains on track for 1H26. Following the strategy update last month (Pipeline but MP), SPRB is focused on advancing tralesinidase alfa, an enzyme replacement therapy (ERT), for the treatment of MPS IIIB. the FDA confirmed in a Type C meeting that HS-NRE (heparan sulfate non-reducing end) is deemed to be a surrogate biomarker reasonably likely to predict clinical benefit and could serve as a basis for Accelerated Approval. The company continues to guide to a Biologics License Application (BLA) submission in the first half of 2026.
RBC Capital Analyst forecast on SPRB
RBC Capital
RBC Capital
$0.5
Hold
-94.99%
Downside
Reiterated
05/06/25
Analysts Conflicted on These Healthcare Names: Spruce Biosciences (Other OTC: SPRB), Cigna (NYSE: CI) and Axsome Therapeutics (NASDAQ: AXSM)
H.C. Wainwright Analyst forecast on SPRB
H.C. Wainwright
H.C. Wainwright
Hold
Reiterated
04/28/25
Spruce Biosciences: Promising Strategy Amidst Financial Challenges and Regulatory Uncertainties
Citizens JMP Analyst forecast on SPRB
Citizens JMP
Citizens JMP
Hold
Reiterated
04/23/25
Citizens JMP reiterates Market Perform Rating on Spruce Biosciences, Inc. (SPRB)Citizens JMP analyst Jonathan Wolleben reiterated a Market Perform rating and {REMOVEPT} price target on Spruce Biosciences, Inc. (NASDAQ: SPRB).
Oppenheimer Analyst forecast on SPRB
Oppenheimer
Oppenheimer
Hold
Downgraded
12/11/24
Spruce Biosciences Downgraded to Hold Amid Unmet Clinical Trial Endpoints and Strategic Reevaluation
Stocks with the Highest Top Analyst Consensus in the Healthcare Sector
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SPRB Analyst Recommendation Trends

Rating
Nov 24
Dec 24
Jan 25
Apr 25
May 25
Strong Buy
0
0
0
0
0
Buy
2
3
2
2
0
Hold
7
10
10
11
7
Sell
2
4
5
4
2
Strong Sell
0
0
0
0
0
total
11
17
17
17
9
In the current month, SPRB has received 0 Buy Ratings, 7 Hold Ratings, and 2 Sell Ratings. SPRB average Analyst price target in the past 3 months is 0.75.
Each month's total comprises the sum of three months' worth of ratings.

SPRB Stock Forecast FAQ

What is SPRB’s average 12-month price target, according to analysts?
Based on analyst ratings, Spruce Biosciences, Inc.’s 12-month average price target is 0.75.
    What is SPRB’s upside potential, based on the analysts’ average price target?
    Currently there's no upside potential for SPRB, based on the analysts’ average price target.
    Can I see which stocks the top-ranking analysts are rating?
    Yes, go to the Analysts’ Top Stocks tool to see stocks with a Strong Buy or Strong Sell analyst rating consensus, according to the top performers.
      How can I follow the stock ratings of top Wall Street analysts?
      Head over to our Expert Center to see a list of the top 100 Wall Street analysts and follow the analysts of your choice. Visit their profiles for more details about their stock ratings and see how they perform on a stock-by-stock basis.
        Is SPRB a Buy, Sell or Hold?
        Spruce Biosciences, Inc. has a consensus rating of Hold which is based on 0 buy ratings, 0 hold ratings and 0 sell ratings.
          What is Spruce Biosciences, Inc.’s price target?
          The average price target for Spruce Biosciences, Inc. is 0.75. This is based on 0 Wall Streets Analysts 12-month price targets, issued in the past 3 months.
          The highest analyst price target is $1.00 ,the lowest forecast is $0.50. The average price target represents -92.48% Decrease from the current price of $9.98.
            What do analysts say about Spruce Biosciences, Inc.?
            Spruce Biosciences, Inc.’s analyst rating consensus is a Hold. This is based on the ratings of 0 Wall Streets Analysts.
              How can I buy shares of SPRB?
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