Clinical DevelopmentSilexion plans to initiate a Phase 2/3 study for SIL-204, with meetings scheduled with regulators to discuss and finalize the study design, indicating progress towards clinical development.
Market PotentialKRAS mutations, which SIL-204 effectively targets, occur in high percentages of pancreatic, colorectal, non-small cell lung, and gastrointestinal cancers, indicating a broad market potential.
Regulatory SupportThe FDA awarding daraxonrasib a CNPV suggests the FDA is highly supportive of the KRAS targeting approach, thus when Silexion eventually files its IND in the U.S., there may be similar support in development.