Persistent Operating Cash BurnMaterial negative operating cash flows indicate the company is cash-consuming and dependent on external capital to fund operations and trials. Over the medium term this constrains autonomy, increases financing and dilution risk, and could slow program timelines if fresh funding is delayed.
Volatile, Declining RevenueSharp, unpredictable revenue declines undermine the foundation for sustainable operations and suggest weak commercial traction or one-off receipts. Continued volatility increases reliance on external funding and limits reinvestment capacity, hindering long-term program and commercial development.
Eroding Equity And Negative ROEDeclining equity and sustained negative ROE indicate persistent value erosion from operating losses. This damages investor returns and can raise the cost of capital, making future fundraising more dilutive and potentially constraining strategic choices over the medium term.