Clinical Trial FailureThe decision to discontinue RLYB212 was based on pharmacokinetic (PK) data from the Phase 2 trial indicating the inability to achieve predicted target concentrations, as well as the minimum target concentration required for efficacy.
Program DiscontinuationRallybio has announced the discontinuation of its RLYB212 program, which was undergoing development for the prevention of fetal and neonatal alloimmune thrombocytopenia (FNAIT).
Stock Valuation ImpactWe are surprised by the negative PK data and consider this a major setback, as the FNAIT program represented the most significant component of our valuation.