Commercial Adoption And Market PathwaysPhysician interest in at-home subcutaneous use and acceptance of clinic administration with buy-and-bill indicate flexible commercial pathways that could accelerate patient adoption across large psoriasis and psoriatic arthritis markets.
ORKA-002 Differentiation And Efficacy PotentialORKA-002's extended half-life and comparable peak exposure to a leading IL-17 therapy suggest the drug could deliver similar efficacy with much less frequent maintenance dosing, improving patient experience in psoriasis and hidradenitis suppurativa.
Pharmacokinetics And DosingExceptional half-life and sustained target inhibition for ORKA-001 support the potential for a once-year dosing regimen that could boost adherence and convenience versus current injectable therapies.