Financial StabilityOruka has completed a private investment in public equity (PIPE) financing resulting in gross proceeds of approximately $180M, providing financial stability and operational runway well into 2028.
Market PositionORKA is the only other clinical-stage IL-17A/F targeted therapy that we are aware of besides MoonLake Immunotherapeutics.
Product PotentialSingle doses of ORKA-001 demonstrated complete and sustained inhibition of STAT3 signaling, a downstream marker of IL-23 activity, in an ex vivo assay through 24 weeks, suggesting potential effectiveness.