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Kazia Therapeutics Limited (KZIA)
NASDAQ:KZIA
US Market

Kazia Therapeutics (KZIA) AI Stock Analysis

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KZIA

Kazia Therapeutics

(NASDAQ:KZIA)

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Neutral 49 (OpenAI - 5.2)
Rating:49Neutral
Price Target:
$7.50
▲(16.46% Upside)
Action:ReiteratedDate:02/28/26
The score is held down primarily by weak financial performance (minimal revenue, large ongoing losses, and persistent cash burn with negative equity). Technicals are a notable offset with strong momentum above major moving averages, but overbought signals add near-term risk; valuation remains challenged due to negative earnings and no dividend support.
Positive Factors
Diversified, brain‑penetrant oncology pipeline
A focused pipeline centered on a brain‑penetrant PI3K/mTOR inhibitor plus next‑gen programs gives durable strategic depth in high‑need CNS and aggressive solid tumors. Successful clinical progression would create lasting competitive differentiation and multiple value inflection points over the next 2–4 years.
Negative Factors
Persistent negative operating cash flow
Sustained negative operating and free cash flow indicates the business cannot self‑fund development and must rely on external capital. Over the medium term this raises funding risk and potential dilution, and magnifies execution risk if trial setbacks or slower enrollment increase cash burn beyond current projections.
Read all positive and negative factors
Positive Factors
Negative Factors
Diversified, brain‑penetrant oncology pipeline
A focused pipeline centered on a brain‑penetrant PI3K/mTOR inhibitor plus next‑gen programs gives durable strategic depth in high‑need CNS and aggressive solid tumors. Successful clinical progression would create lasting competitive differentiation and multiple value inflection points over the next 2–4 years.
Read all positive factors

Kazia Therapeutics (KZIA) vs. SPDR S&P 500 ETF (SPY)

Kazia Therapeutics Business Overview & Revenue Model

Company Description
Kazia Therapeutics Limited, an oncology-focused biotechnology company, develops anti-cancer drugs. Its lead development candidate is Paxalisib, a small molecule, brain-penetrant inhibitor of the PI3K/Akt/mTor pathway, which is developed as a poten...
How the Company Makes Money
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Kazia Therapeutics Financial Statement Overview

Summary
Financials are very weak: revenue is extremely small and volatile (down to ~$42K in 2025 from ~$2.3M in 2024), losses remain large (net loss ~$20.7M in 2025), and operating/free cash flow are consistently negative (FCF about -$13.3M in 2025). Low absolute debt helps, but negative equity and a shrinking asset base materially raise funding and execution risk.
Income Statement
12
Very Negative
Balance Sheet
28
Negative
Cash Flow
20
Very Negative
BreakdownTTMJun 2025Jun 2024Jun 2023Jun 2022Jun 2021
Income Statement
Total Revenue19.71K42.00K2.31M555.0010.00K15.18M
Gross Profit19.71K42.00K2.31M555.0010.00K15.18M
EBITDA-18.15M-13.28M-26.59M-22.28M-23.52M-5.11M
Net Income-22.27M-20.70M-26.78M-20.47M-25.01M-8.42M
Balance Sheet
Total Assets71.04M6.06M21.59M28.08M35.89M58.09M
Cash, Cash Equivalents and Short-Term Investments69.39M4.34M1.66M5.24M7.36M27.59M
Total Debt98.71K396.00K634.00K1.80M1.84M0.00
Total Liabilities24.62M14.36M31.60M16.03M17.61M20.24M
Stockholders Equity46.42M-8.30M-10.02M12.05M18.27M37.85M
Cash Flow
Free Cash Flow-9.07M-13.28M-9.58M-15.16M-22.76M-9.11M
Operating Cash Flow-13.22M-13.28M-9.58M-15.16M-22.76M-9.11M
Investing Cash Flow0.000.000.000.00-2.37M0.00
Financing Cash Flow79.08M15.98M5.99M12.97M3.73M28.11M

Kazia Therapeutics Technical Analysis

Technical Analysis Sentiment
Neutral
Last Price6.44
Price Trends
50DMA
7.08
Positive
100DMA
7.92
Negative
200DMA
7.90
Negative
Market Momentum
MACD
-0.05
Positive
RSI
48.78
Neutral
STOCH
45.87
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For KZIA, the sentiment is Neutral. The current price of 6.44 is below the 20-day moving average (MA) of 7.57, below the 50-day MA of 7.08, and below the 200-day MA of 7.90, indicating a neutral trend. The MACD of -0.05 indicates Positive momentum. The RSI at 48.78 is Neutral, neither overbought nor oversold. The STOCH value of 45.87 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Neutral sentiment for KZIA.

Kazia Therapeutics Risk Analysis

Kazia Therapeutics disclosed 37 risk factors in its most recent earnings report. Kazia Therapeutics reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 3 New Risks
1.
Holders of the ADSs are not treated as holders of our ordinary shares. Q2, 2024
2.
We have a history of operating losses and we expect to continue to incur losses and may never be profitable. Q2, 2024
3.
If the Company fails to comply with the rules under the Sarbanes-Oxley Act of 2002 related to accounting controls and procedures in the future, or, if the Company discovers material weaknesses and other deficiencies in our internal control and accounting procedures, the price of the ADSs could decline significantly and raising capital could be more difficult. Q2, 2024

Kazia Therapeutics Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
51
Neutral
$14.64M-0.72-107.58%83.95%
49
Neutral
$83.21M-0.65-116.86%-98.25%63.05%
$6.01M-5.5665.45%
49
Neutral
$8.22M-0.46-684.86%96.75%
44
Neutral
$23.51M-3.35>-0.01%-12.99%-13.67%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
KZIA
Kazia Therapeutics
7.34
3.87
111.53%
PHIO
Phio Pharmaceuticals
1.26
0.25
24.75%
XTLB
XTL Biopharmaceuticals Sponsored ADR
2.49
-2.23
-47.25%
MRKR
Marker Therapeutics
1.41
0.36
34.29%
RNAZ
TransCode Therapeutics
8.96
-1.90
-17.50%

Kazia Therapeutics Corporate Events

Kazia Therapeutics Announces Board Changes and AGM Outcomes as It Highlights Oncology Pipeline
Apr 1, 2026
On March 26, 2026, Kazia Therapeutics Limited, a Sydney-based clinical-stage oncology company focused on high-need CNS cancers and aggressive solid tumors, announced that Chairman Bryce Carmine had notified the board of his intention to retire. Hi...
Kazia Therapeutics Taps Leerink for New ATM Facility as Cash Bolstered by Late-2025 PIPE
Mar 30, 2026
Kazia Therapeutics Limited, an Australian oncology-focused RD company developing assets such as paxalisib and EVT801 and listed on Nasdaq via ADSs, reported a net loss of $12.6 million for the half year to 31 December 2025, with operating cash out...
Kazia Therapeutics Posts Wider Half-Year Loss but Bolsters Cash, Pipeline and Nasdaq Compliance
Mar 19, 2026
Kazia Therapeutics reported unaudited half-year results for the six months to December 31, 2025, on March 16, 2026, showing a post-tax loss of $12.55 million, widening from $10.45 million a year earlier. Despite higher operating losses and cash ou...
Kazia Therapeutics Posts Early Efficacy Signals for Paxalisib Combo in Metastatic Triple-Negative Breast Cancer
Jan 27, 2026
On January 27, 2026, Kazia Therapeutics reported encouraging early clinical signals from an ongoing Phase 1b trial of paxalisib in combination with pembrolizumab and chemotherapy in late-stage metastatic triple-negative breast cancer, initiated in...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Feb 28, 2026