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Bristol-Myers Squibb (IT:1BMY)
:1BMY
Atezolizumab, Bevacizumab, Ipilimumab, Pumitamig
Hepatocellular Carcinoma (Hcc)
Phase I/II
Not Yet Recruiting
A Study to Evaluate the Safety and Tolerability of Pumitamig Alone or In Combination With Ipilimumab in Participants With First-Line Advanced or Unresectable Hepatocellular Carcinoma (HCC) (ROSETTA HCC-206)
Dec 17, 2025
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Gemcitabine, Cetuximab, Pembrolizumab, Nab-paclitaxel, Bms-986523
Non-Small Cell Lung Cancer (Nsclc), Advanced Solid Malignancies, Colorectal Cancer (Crc), Pancreatic Ductal Adenocarcinoma (Pdac)
Phase I/II
Recruiting
A Study to Evaluate the Safety, Tolerability, and Efficacy of BMS-986523 Alone and in Combination With Anti-Cancer Agents in Participants With Advanced Solid Malignancies
Oct 29, 2025
Nivolumab, Folfox, Pumitamig, Capox
Untreated Advanced Or Metastatic Gastric, Gastroesophageal Junction, Or Esophageal Adenocarcinoma
Phase II/III
Not Yet Recruiting
A Study to Evaluate the Safety and Efficacy of Pumitamig in Combination With Chemotherapy Versus Nivolumab in Combination With Chemotherapy in Participants With Previously Untreated Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma
Oct 23, 2025
Bevacizumab, Folfiri, Folfox, Pumitamig, Capox
Untreated, Unresectable, Or Metastatic Colorectal Cancer
Phase II/III
Recruiting
A Study to Evaluate the Safety and Efficacy of Pumitamig in Combination With Chemotherapy Versus Bevacizumab in Combination With Chemotherapy in Participants With Previously Untreated, Unresectable, or Metastatic Colorectal Cancer
Oct 23, 2025
Lamotrigine, Xanomeline/Trospium Chloride, Lithium, Valproate
Bipolar Disorder, Mania
Phase III
Recruiting
A Study to Evaluate the Efficacy and Safety of Adjunctive KarXT for the Treatment of Mania, With or Without Mixed Features, in Participants With Bipolar-I Disorder Taking Lithium, Valproate, or Lamotrigine
Aug 21, 2025
FAQ
What are the FDA phases for drug approval?
The FDA approval process for new drugs is divided into several phases:
a. Preclinical testing
b. Phase 1 – Safety and dosage
c. Phase 2 – Effectiveness and side effects
d. Phase 3 – Confirmation of effectiveness, monitoring of adverse reactions, and comparison with existing treatments
e. Phase 4 – Post-marketing studies to track long-term safety and effectiveness
a. Preclinical testing
b. Phase 1 – Safety and dosage
c. Phase 2 – Effectiveness and side effects
d. Phase 3 – Confirmation of effectiveness, monitoring of adverse reactions, and comparison with existing treatments
e. Phase 4 – Post-marketing studies to track long-term safety and effectiveness
What is a clinical trial?
A clinical trial is a carefully designed study in which researchers test a drug, treatment, or medical device in people to evaluate its safety, effectiveness, and potential side effects. These trials are essential for determining whether a new treatment should be approved for widespread use.
What drugs does Bristol-Myers Squibb (1BMY) have in its pipeline
1BMY is currently developing the following drugs: Atezolizumab, Bevacizumab, Ipilimumab, Pumitamig, Karxt, Gemcitabine, Cetuximab, Pembrolizumab, Nab-paclitaxel, Bms-986523. These drug candidates are in various stages of clinical development as the company works toward FDA approval.