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International Stem Cell (ISCO)
OTHER OTC:ISCO
US Market

International Stem Cell (ISCO) AI Stock Analysis

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ISCO

International Stem Cell

(OTC:ISCO)

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Neutral 49 (OpenAI - 5.2)
Rating:49Neutral
Price Target:
$0.16
▲(32.50% Upside)
Action:ReiteratedDate:03/31/26
The score is held back mainly by weak financial performance—persistent losses, deteriorating recent free cash flow, and a higher-risk balance sheet with periods of negative equity. Technicals are modestly supportive with the price above major moving averages, and valuation appears favorable on a low P/E, but these are not enough to offset the fundamental risk profile.
Positive Factors
Gross margin sustainability
Consistently high gross margins indicate the company’s products/services have durable unit economics. That margin buffer supports gross profitability even with volatile revenue, giving management room to invest in R&D or sales while pursuing a path to operating leverage if top-line stabilizes.
Negative Factors
Weak balance sheet
Repeated periods of negative equity and materially fluctuating debt create financial fragility. That weak capitalization reduces flexibility to fund R&D or scale, raises refinancing and covenant risk, and can deter large partners or investors for longer-term projects.
Read all positive and negative factors
Positive Factors
Negative Factors
Gross margin sustainability
Consistently high gross margins indicate the company’s products/services have durable unit economics. That margin buffer supports gross profitability even with volatile revenue, giving management room to invest in R&D or sales while pursuing a path to operating leverage if top-line stabilizes.
Read all positive factors

International Stem Cell (ISCO) vs. SPDR S&P 500 ETF (SPY)

International Stem Cell Business Overview & Revenue Model

Company Description
International Stem Cell Corporation, a clinical stage biotechnology company, focuses on the development of therapeutic and biomedical products in North America, Asia, Europe, and internationally. The company's products are based on human parthenog...
How the Company Makes Money
ISCO has historically generated revenue through multiple sources tied to its stem cell platforms: (1) sales of stem cell–related products and services (e.g., cell lines, cell-based materials, and/or contract services supporting research and develo...

International Stem Cell Financial Statement Overview

Summary
Gross margins are consistently healthy (~56%–61%), but profitability remains weak with persistent net losses and a sharp 2025 revenue decline versus 2024. The balance sheet is the biggest risk due to periods of negative equity and volatile leverage, while cash flow weakened in 2024–2025 with negative free cash flow after a stronger 2023.
Income Statement
34
Negative
Balance Sheet
22
Negative
Cash Flow
28
Negative
BreakdownTTMDec 2025Mar 2025Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue9.39M9.10M9.09M7.79M8.18M7.18M
Gross Profit5.43M5.07M5.32M4.61M4.91M4.24M
EBITDA279.00K-267.00K142.00K202.00K22.00K-220.00K
Net Income-59.00K-418.00K-209.00K-131.00K-466.00K-1.04M
Balance Sheet
Total Assets5.28M4.82M5.17M5.39M5.13M4.95M
Cash, Cash Equivalents and Short-Term Investments966.00K993.00K1.23M1.59M742.00K171.00K
Total Debt3.89M393.00K3.84M4.18M4.28M4.07M
Total Liabilities4.76M4.58M9.10M5.28M9.65M9.53M
Stockholders Equity524.00K240.00K-3.93M113.00K-4.52M-4.59M
Cash Flow
Free Cash Flow-141.00K-35.00K-153.00K846.00K321.00K-1.34M
Operating Cash Flow-98.00K8.00K13.00K929.00K332.00K-1.30M
Investing Cash Flow-43.00K-45.00K-171.00K-83.00K-11.00K-45.00K
Financing Cash Flow-200.00K-200.00K-200.00K0.00250.00K824.00K

International Stem Cell Technical Analysis

Technical Analysis Sentiment
Positive
Last Price0.12
Price Trends
50DMA
0.15
Positive
100DMA
0.15
Positive
200DMA
0.15
Positive
Market Momentum
MACD
<0.01
Negative
RSI
53.67
Neutral
STOCH
82.40
Negative
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For ISCO, the sentiment is Positive. The current price of 0.12 is below the 20-day moving average (MA) of 0.15, below the 50-day MA of 0.15, and below the 200-day MA of 0.15, indicating a bullish trend. The MACD of <0.01 indicates Negative momentum. The RSI at 53.67 is Neutral, neither overbought nor oversold. The STOCH value of 82.40 is Negative, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for ISCO.

International Stem Cell Risk Analysis

International Stem Cell disclosed 47 risk factors in its most recent earnings report. International Stem Cell reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

International Stem Cell Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
49
Neutral
$1.28M-2.683.33%10.12%79.74%
49
Neutral
$473.41K-0.24178.82%-4121.10%
41
Neutral
$1.38M-148.02-63.03%-100.00%86.75%
$2.18M-0.17-168.95%90.27%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
ISCO
International Stem Cell
0.17
0.05
41.67%
BDRX
Biodexa Pharmaceuticals
0.62
-11.38
-94.86%
QCLS
Q/C Technologies
3.45
-40.74
-92.19%
SCNI
Scinai Immunotherapeutics
0.57
-2.24
-79.72%
OGEN
Oragenics
0.56
-5.81
-91.21%
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Mar 31, 2026