Strong Revenue Growth
Total operating income for Q1 2025 was $807 million, reflecting a 99% growth in product net sales compared to the prior year quarter. The U.S. contributed $681 million, Japan $32 million, and the rest of the world $57 million.
VYVGART Expansion Success
The company successfully launched the pre-filled syringe for VYVGART in the U.S. and Germany, contributing to patient growth in gMG and CIDP markets. VYVGART achieved the fastest market share growth among branded biologics in gMG.
Positive Clinical Data
New data from the ADVANCE-NEXT study showed 56.5% of gMG patients achieved minimum symptom expression during treatment. VYVGART continues to demonstrate sustained efficacy and improved quality of life measures.
Financial Strength
The company reported a gross margin of 90% and an operating profit of $139 million for Q1 2025. The cash balance at quarter-end was $3.6 billion, an increase of $238 million from Q4 2024.
Pipeline Progress
Argenx is advancing 10 registrational and 10 proof-of-concept studies, including Phase III assets and INDs for ARGX-109 and ARGX-213. The company plans several readouts across its pipeline for the year.