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Transgene SA (FR:TNG)
:TNG

Transgene (TNG) AI Stock Analysis

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FR:TNG

Transgene

(TNG)

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Neutral 50 (OpenAI - 5.2)
Rating:50Neutral
Price Target:
€0.75
▼(-19.79% Downside)
Action:ReiteratedDate:03/26/26
The score is held down primarily by weak financial performance (ongoing losses and cash burn) and bearish technicals (downtrend with negative MACD). These are partly offset by a constructive earnings call centered on strengthened liquidity/runway and promising early clinical signals, while valuation is inconclusive due to negative earnings and no dividend.
Positive Factors
Balance sheet & runway
The December 2025 EUR 105m raise and EUR 39m debt conversion materially strengthened liquidity and left Transgene with minimal leverage. This improved capitalization provides financial visibility into early 2028, lowering near-term financing risk, enabling continued R&D and GMP investments and preserving partnering optionality over the medium term.
Negative Factors
Cash burn & weak cash flow
Transgene reported negative operating cash flow (~EUR -36.7m in 2025) and ongoing negative free cash flow, meaning operations consume cash rather than generate it. Even with current runway into early 2028, persistent cash burn implies reliance on future financings or partnerships, creating dilution and execution risk beyond the near term.
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Positive Factors
Negative Factors
Balance sheet & runway
The December 2025 EUR 105m raise and EUR 39m debt conversion materially strengthened liquidity and left Transgene with minimal leverage. This improved capitalization provides financial visibility into early 2028, lowering near-term financing risk, enabling continued R&D and GMP investments and preserving partnering optionality over the medium term.
Read all positive factors

Transgene (TNG) vs. iShares MSCI France ETF (EWQ)

Transgene Business Overview & Revenue Model

Company Description
Transgene SA, a biotechnology company, focuses on designing and developing therapeutic vaccines and oncolytic viruses for the treatment of cancer and infectious diseases. It is involved in developing TG4050, a therapeutic vaccine that is in phase ...
How the Company Makes Money
Transgene primarily makes money through (1) collaboration and partnership revenue and (2) other operating income, while it funds most activities through financing as a clinical-stage R&D company. Key revenue streams: - Collaboration / licensing /...

Transgene Earnings Call Summary

Earnings Call Date:Mar 24, 2026
(Q4-2025)
|
% Change Since: |
Next Earnings Date:Apr 29, 2026
Earnings Call Sentiment Positive
The call emphasized several strong positives: robust fundraising (EUR 105M), a strengthened balance sheet (EUR 39M debt conversion), compelling Phase I efficacy and durable immunogenicity signals for TG4050 (100% disease-free in treated Phase I patients; 73% immunogenicity with responses persisting 24 months), encouraging BT-001 combination data, and a clear plan for manufacturing and regulatory readiness. Counterbalancing these highlights are timing and operational risks (GMP readiness targeted Q3 2027), immature/pending pivotal readouts (Phase II 2-year DFS not yet available), ongoing cash burn (~EUR 38.2M in 2025) and some dependence on broader field validation. Overall, the positive clinical signals and strengthened financial position outweigh the execution and timing risks at this stage.
Positive Updates
Successful Fundraising and Balance Sheet Strengthening
Raised approximately EUR 105 million in December 2025 and converted EUR 39 million of debt into equity, leaving the company virtually debt-free and providing financial visibility/runway through early 2028.
Negative Updates
Key Efficacy Readouts Not Yet Mature or Fully Peer-Reviewed
Primary efficacy readout for Phase I/II (2-year DFS for Phase II) is pending until patients reach 2 years post-randomization; Phase I comprehensive analysis is currently a preprint under peer review, so data are not yet fully validated by peer-reviewed publication.
Read all updates
Q4-2025 Updates
Negative
Successful Fundraising and Balance Sheet Strengthening
Raised approximately EUR 105 million in December 2025 and converted EUR 39 million of debt into equity, leaving the company virtually debt-free and providing financial visibility/runway through early 2028.
Read all positive updates
Company Guidance
The call laid out clear, metric-driven guidance: Transgene raised ~EUR 105m in December 2025 and converted ~EUR 39m of debt to equity (now virtually debt‑free), giving cash visibility through early 2028 (first quarter 2028) after a 2025 cash burn of ~EUR 38.2m; clinically, the primary endpoint for the randomized Phase I/II TG4050 study is 2‑year disease‑free survival (DFS) with an efficacy readout once all patients reach 2 years, Phase I 3‑year DFS data expected Q2–Q3 2026 and 4‑year follow‑up Q2–Q3 2027, Phase II patient randomization to be completed by Q2 2026 and first Phase II immunogenicity data in H2 2026 (with ~1 year follow‑up possible), and Phase I translational results showed 100% DFS at ≥2 years in treated HPV‑negative HNSCC patients vs. 3 relapses in controls and neoantigen‑specific T‑cell responses in 73% of evaluable patients that persisted 24 months; manufacturing and regulatory investments target full GMP capacity by Q3 2027 and a second Phase I indication is slated to start in 2026.

Transgene Financial Statement Overview

Summary
Overall financials are weak: persistent operating/net losses, sharply lower 2025 revenue, and continued negative operating cash flow and free cash flow. The main offset is a comparatively strong balance sheet with very low leverage and a large 2025 equity base, but ongoing cash burn keeps financing/dilution risk elevated.
Income Statement
14
Very Negative
Balance Sheet
63
Positive
Cash Flow
21
Negative
BreakdownDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue137.00K6.35M7.90M3.13M9.99M
Gross Profit0.00-27.93M-21.69M-29.04M-22.89M
EBITDA-39.77M-26.65M-28.44M-30.33M-23.55M
Net Income-37.52M-33.97M-22.33M-32.81M-20.00M
Balance Sheet
Total Assets138.83M42.17M45.22M66.44M101.84M
Cash, Cash Equivalents and Short-Term Investments111.86M16.67M15.67M26.83M49.57M
Total Debt2.06M10.40M1.35M2.45M3.84M
Total Liabilities17.09M26.97M29.61M28.59M34.63M
Stockholders Equity121.73M15.20M15.61M37.84M67.21M
Cash Flow
Free Cash Flow-37.58M-26.62M-37.42M-21.84M-32.63M
Operating Cash Flow-36.74M-23.55M-34.67M-20.30M-31.94M
Investing Cash Flow-105.95M-3.21M34.57M20.27M16.79M
Financing Cash Flow134.38M26.96M11.37M-1.48M15.77M

Transgene Technical Analysis

Technical Analysis Sentiment
Negative
Last Price0.94
Price Trends
50DMA
0.84
Negative
100DMA
0.95
Negative
200DMA
1.00
Negative
Market Momentum
MACD
-0.03
Positive
RSI
38.63
Neutral
STOCH
35.33
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For FR:TNG, the sentiment is Negative. The current price of 0.94 is above the 20-day moving average (MA) of 0.79, above the 50-day MA of 0.84, and below the 200-day MA of 1.00, indicating a bearish trend. The MACD of -0.03 indicates Positive momentum. The RSI at 38.63 is Neutral, neither overbought nor oversold. The STOCH value of 35.33 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for FR:TNG.

Transgene Peers Comparison

Overall Rating
UnderperformOutperform
Sector (55)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
58
Neutral
€414.69M-4.08-63.70%-45.41%-273.69%
55
Neutral
$6.65B3.83-15.92%6.20%10.91%7.18%
52
Neutral
€1.28B-9.10
50
Neutral
€205.43M-3.69-634.16%111.76%-22.45%
49
Neutral
€68.15M-1.87-52.76%-96.92%-175.84%
45
Neutral
€985.15M-3.62-241.12%3.09%
44
Neutral
€103.13M-2.91-658.91%-75.86%-30.54%
* General Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
FR:TNG
Transgene
0.75
0.09
13.33%
FR:GNFT
Genfit
8.31
5.00
151.29%
FR:IPH
Innate Pharma SA
1.08
-0.74
-40.62%
FR:DBV
DBV Technologies
3.52
2.39
212.61%
FR:NANO
Nanobiotix
26.95
23.65
716.67%
FR:OSE
OSE Immunotherapeutics SA
3.08
-2.53
-45.17%
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Mar 26, 2026