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Valerio Therapeutics (FR:ALVIO)
:ALVIO
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Valerio Therapeutics (ALVIO) AI Stock Analysis

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FR:ALVIO

Valerio Therapeutics

(ALVIO)

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Neutral 55 (OpenAI - 5.2)
Rating:55Neutral
Price Target:
€0.16
▲(170.00% Upside)
Action:ReiteratedDate:05/03/26
The score is driven by improving 2025 fundamentals (revenue growth and a shift to positive operating/free cash flow), supported by strong technical momentum with price above major moving averages. These positives are offset by high leverage and continued net losses, while valuation is constrained by a negative P/E and no dividend support.
Positive Factors
Revenue rebound & strong gross margins
A ~40.6% revenue rebound in 2025 combined with sustained ~67–71% gross margins signals improving commercial traction or milestone/licensing progress and an underlying scalable cost structure. For a clinical biotech this supports reinvestment in R&D and improves the odds of reaching durable profitability if growth persists.
Negative Factors
Elevated leverage and balance-sheet volatility
Materially higher leverage and swings in equity reflect balance-sheet fragility. High debt-to-equity (~3.7x) constrains financial flexibility, increases refinancing and interest risk, and limits capacity to absorb clinical setbacks. This elevates funding risk for capital-intensive trials over the medium term.
Read all positive and negative factors
Positive Factors
Negative Factors
Revenue rebound & strong gross margins
A ~40.6% revenue rebound in 2025 combined with sustained ~67–71% gross margins signals improving commercial traction or milestone/licensing progress and an underlying scalable cost structure. For a clinical biotech this supports reinvestment in R&D and improves the odds of reaching durable profitability if growth persists.
Read all positive factors

Valerio Therapeutics (ALVIO) vs. iShares MSCI France ETF (EWQ)

Valerio Therapeutics Business Overview & Revenue Model

Company Description
Valerio Therapeutics Société anonyme, a clinical-stage biotechnology company, designs and develops oncology drugs for tumor DNA repair functions worldwide. The company offers Beleodaq for the treatment of peripheral T-cell lymphoma. It also develo...
How the Company Makes Money
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Valerio Therapeutics Financial Statement Overview

Summary
2025 shows a clear operational inflection with revenue up ~40.6% and gross margin staying strong (~67–71%), plus operating cash flow (~1.8M) and free cash flow (~0.5M) turning positive. Offsetting this, profitability remains negative (net income ~-4.9M) and balance-sheet risk is elevated with high leverage (debt-to-equity ~3.7x) and recent equity volatility.
Income Statement
33
Negative
Balance Sheet
24
Negative
Cash Flow
41
Neutral
BreakdownDec 2025Jun 2025Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue2.57M1.79M1.80M1.44M4.06M
Gross Profit1.73M1.28M1.27M929.00K3.69M
EBITDA542.00K-12.06M-18.44M-17.04M-5.86M
Net Income-4.90M-23.93M-20.34M-19.56M-5.94M
Balance Sheet
Total Assets15.23M17.93M35.27M43.09M53.06M
Cash, Cash Equivalents and Short-Term Investments1.05M1.18M6.82M14.59M17.89M
Total Debt7.61M13.44M9.00M10.09M9.94M
Total Liabilities13.16M26.19M20.47M20.82M20.12M
Stockholders Equity2.08M-8.93M14.80M22.27M32.94M
Cash Flow
Free Cash Flow521.00K-12.78M-18.78M-9.93M-8.71M
Operating Cash Flow1.84M-12.46M-18.60M-9.44M-8.57M
Investing Cash Flow-1.16M-1.39M-177.00K-409.00K-66.00K
Financing Cash Flow-774.00K4.21M10.76M6.46M11.98M

Valerio Therapeutics Technical Analysis

Technical Analysis Sentiment
Positive
Last Price0.06
Price Trends
50DMA
0.14
Positive
100DMA
0.14
Positive
200DMA
0.11
Positive
Market Momentum
MACD
<0.01
Negative
RSI
62.44
Neutral
STOCH
83.48
Negative
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For FR:ALVIO, the sentiment is Positive. The current price of 0.06 is below the 20-day moving average (MA) of 0.12, below the 50-day MA of 0.14, and below the 200-day MA of 0.11, indicating a bullish trend. The MACD of <0.01 indicates Negative momentum. The RSI at 62.44 is Neutral, neither overbought nor oversold. The STOCH value of 83.48 is Negative, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for FR:ALVIO.

Valerio Therapeutics Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
55
Neutral
€84.76M-1.14146.07%-3.12%30.49%
53
Neutral
€231.30M-4.66-30.75%66.75%-103.90%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
50
Neutral
€216.26M-2.10-634.16%291.43%12.24%
49
Neutral
€86.72M-1.28-52.76%-96.28%-197.89%
45
Neutral
€18.91M-0.9751.23%-99.93%44.53%
44
Neutral
€117.75M-1.31-658.91%-77.92%11.11%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
FR:ALVIO
Valerio Therapeutics
0.17
0.11
174.19%
FR:IPH
Innate Pharma SA
1.25
-0.76
-37.61%
FR:TNG
Transgene
0.78
0.19
31.76%
FR:OSE
OSE Immunotherapeutics SA
3.87
-2.10
-35.24%
FR:SIGHT
GenSight Biologics SA
0.08
-0.14
-62.96%
FR:ALCLS
Cellectis SA
3.20
1.85
136.89%
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: May 03, 2026