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Valerio Therapeutics (FR:ALVIO)
:ALVIO
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Valerio Therapeutics (ALVIO) AI Stock Analysis

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FR:ALVIO

Valerio Therapeutics

(LSE:ALVIO)

Rating:43Neutral
Price Target:
€0.00
▼(-100.00% Downside)
Valerio Therapeutics is facing significant financial challenges, with declining revenues and negative profitability margins being the most impactful factors. The technical analysis shows neutral indicators, while the valuation is unattractive due to a negative P/E ratio and no dividend yield. These factors collectively result in a low overall stock score.

Valerio Therapeutics (ALVIO) vs. iShares MSCI France ETF (EWQ)

Valerio Therapeutics Business Overview & Revenue Model

Company DescriptionValerio Therapeutics Société anonyme, a clinical-stage biotechnology company, designs and develops oncology drugs for tumor DNA repair functions worldwide. The company offers Beleodaq for the treatment of peripheral T-cell lymphoma. It also develops AsiDNA, which is in Phase 1 clinical trial for the treatment of metastatic melanoma; OX401, which is in preclinical stage for treating DNA damage response and immuno-oncology; and platON, a decoy oligonucleotide platform. It has a license agreement with Acrotech Biopharma LLC; and clinical research agreement with Gustave Roussy to conduct clinical trial of AsiDNA for the treatment of relapsed ovarian cancer. The company was formerly known as Onxeo SA and changed its name to Valerio Therapeutics Société anonyme in June 2023. Valerio Therapeutics Société anonyme was incorporated in 1997 and is headquartered in Paris, France.
How the Company Makes MoneyValerio Therapeutics generates revenue primarily through the development and commercialization of its therapeutic products. This includes income from collaborations and partnerships with pharmaceutical companies that may involve licensing agreements, milestone payments, and royalties on sales of products developed through these collaborations. Additionally, the company may receive funding from grants and public investments aimed at supporting innovative healthcare solutions. The successful advancement of its drug candidates through clinical trials and eventual market approval plays a critical role in the company's financial performance.

Valerio Therapeutics Financial Statement Overview

Summary
Valerio Therapeutics faces significant financial challenges, with declining revenues, negative profitability margins, and high leverage. The negative equity and cash flow issues further highlight financial instability.
Income Statement
35
Negative
Valerio Therapeutics shows declining revenue with a negative revenue growth rate of -5.08% in the latest year. The gross profit margin is relatively strong at 71.39%, but the company suffers from significant net losses, reflected in a net profit margin of -13.35%. The EBIT and EBITDA margins are also negative, indicating operational challenges.
Balance Sheet
20
Very Negative
The company has a negative stockholders' equity, leading to a concerning debt-to-equity ratio of -1.50. This indicates financial instability and high leverage. The return on equity is positive at 2.68%, but this is due to the negative equity, which is not a healthy sign.
Cash Flow
30
Negative
Valerio Therapeutics has negative operating and free cash flows, with a free cash flow growth rate of -22.25%. The operating cash flow to net income ratio is negative, indicating cash flow issues. However, the free cash flow to net income ratio is slightly above 1, suggesting that free cash flow is somewhat aligned with net income.
BreakdownDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue1.79M1.80M1.44M4.06M1.78M
Gross Profit1.28M1.27M929.00K3.69M-166.00K
EBITDA-12.06M-18.44M-17.04M-4.90M2.33M
Net Income-23.93M-20.34M-19.56M-5.94M1.09M
Balance Sheet
Total Assets17.93M35.27M43.09M53.06M46.51M
Cash, Cash Equivalents and Short-Term Investments1.18M6.82M14.59M17.89M14.52M
Total Debt13.44M9.00M10.09M14.76M6.26M
Total Liabilities26.19M20.47M20.82M20.12M17.47M
Stockholders Equity-8.93M14.80M22.27M32.94M29.04M
Cash Flow
Free Cash Flow-12.78M-18.78M-9.93M-8.71M-4.80M
Operating Cash Flow-12.46M-18.60M-9.44M-8.57M-4.68M
Investing Cash Flow-1.39M-177.00K-409.00K-66.00K6.01M
Financing Cash Flow4.21M10.76M6.46M11.98M7.48M

Valerio Therapeutics Technical Analysis

Technical Analysis Sentiment
Negative
Last Price0.06
Price Trends
50DMA
0.06
Negative
100DMA
0.06
Negative
200DMA
0.07
Negative
Market Momentum
MACD
>-0.01
Positive
RSI
41.91
Neutral
STOCH
22.22
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For FR:ALVIO, the sentiment is Negative. The current price of 0.06 is below the 20-day moving average (MA) of 0.06, below the 50-day MA of 0.06, and below the 200-day MA of 0.07, indicating a bearish trend. The MACD of >-0.01 indicates Positive momentum. The RSI at 41.91 is Neutral, neither overbought nor oversold. The STOCH value of 22.22 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for FR:ALVIO.

Valerio Therapeutics Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
51
Neutral
$7.95B-0.40-41.62%2.21%22.29%-1.85%
43
Neutral
€21.12M-814.67%-0.39%3.51%
€6.04M
€9.86M
€4.07M
€20.27M
€17.16M-313.76%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
FR:ALVIO
Valerio Therapeutics
0.06
-0.02
-24.05%
DE:3HB
Hybrigenics SA Class A
0.02
0.00
0.00%
DE:0N6A
TME Pharma N.V.
0.10
0.00
0.00%
DE:6XB3
Biophytis SA
0.15
-0.33
-68.75%
DE:3VG
Theranexus SA
2.45
1.89
337.50%
DE:82F
NFL Biosciences SA
1.26
-0.93
-42.47%
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Aug 27, 2025