Progress in Ziftomenib Development
Ziftomenib's FDA review for relapsed and refractory NPM1-mutated AML is on track with a PDUFA target action date of November 30, 2025. The drug has shown promising clinical data with a differentiated and favorable benefit-risk profile.
Advancements in Clinical Trials
Kura has advanced its KOMET-017 Phase III trials for ziftomenib in frontline settings with over 150 global sites targeted for enrollment. The trials aim to establish ziftomenib as a cornerstone therapy in AML treatment.
Strong Financial Position
Kura reported pro forma cash of $609.7 million, including recent milestone payments, sufficient to fund operations through 2027.
Farnesyl Transferase Inhibitor Potential
Positive clinical data for FTIs, including darlafarnib, show potential for combinations with major targeted therapies, representing a substantial commercial opportunity.