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Clearside Biomedical (CLSD)
NASDAQ:CLSD
Aflibercept, Cls-Ax
Neovascular Age-Related Macular Degeneration
Phase II
Completed
Study to Evaluate Suprachoroidally Administered CLS-AX in the Treatment of Neovascular Age-Related Macular Degeneration
May 24, 2023
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Cls-Ax, Anti-Vegf
Neovascular Age-Related Macular Degeneration
Phase I/II
Completed
Safety and Tolerability Study of Suprachoroidal Injection of CLS-AX Following Anti-VEGF Therapy in Neovascular AMD
Nov 02, 2020
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Suprachoroidal Cls-Ta, Suprachoroidal Sham, Lucentis Or Avastin
Macular Edema, Retinal Vein Occlusion
Phase III
Terminated
Suprachoroidal Injection of Triamcinolone Acetonide With IVT Anti-VEGF in Subjects With Macular Edema Following RVO
Jun 28, 2017
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Ivt Aflibercept, Sc Cls-Ta, Sham Sc
Diabetic Macular Edema
Phase II
Completed
Suprachoroidal CLS-TA With Intravitreal Aflibercept Versus Aflibercept Alone in Subject With Diabetic Macular Edema
Apr 20, 2017
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4 Mg Cls-Ta Suprachoriodal Injection
Uveitis, Panuveitis, Uveitis, Posterior, Uveitis, Anterior, Uveitis, Intermediate
Phase III
Completed
Suprachoroidal Injection of CLS-TA in Patients With Non-infectious Uveitis
Mar 27, 2017
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Ivt Aflibercept, Suprachoroidal Cls-Ta, Suprachoroidal Sham
Macular Edema, Retinal Vein Occlusion
Phase III
Terminated
Suprachoroidal Injection of Triamcinolone Acetonide With IVT Aflibercept in Subjects With Macular Edema Following RVO
Nov 30, 2016
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Ivt Aflibercept, Sc Cls-Ta
Diabetic Macular Edema
Phase I/II
Completed
Suprachoroidal Injection of CLS-TA Alone or With Aflibercept in Subjects With Diabetic Macular Edema
Oct 25, 2016
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4Mg Cls-Ta Suprachoriodal Injection, Sham Procedure
Uveitis, Panuveitis, Uveitis, Posterior, Uveitis, Anterior, Uveitis, Intermediate
Phase III
Completed
Suprachoroidal Injection of CLS-TA in Subjects With Macular Edema Associated With Non-infectious Uveitis
Oct 28, 2015
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Sham, 4 Mg Cls-Ta, Ivt Aflibercept
Macular Edema, Retinal Vein Occlusion
Phase II
Completed
Suprachoroidal Injection of Triamcinolone Acetonide With IVT Aflibercept in Subjects With Macular Edema Following RVO
Nov 25, 2014
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4 Mg Cls-Ta, 0.8 Mg Cls-Ta
Macular Edema, Uveitis, Panuveitis, Uveitis, Posterior, Uveitis, Anterior, Uveitis, Intermediate
Phase II
Completed
Suprachoroidal Injection of Triamcinolone Acetonide in Subjects With Macular Edema Following Non-Infectious Uveitis
Sep 30, 2014
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FAQ
What are the FDA phases for drug approval?
The FDA approval process for new drugs is divided into several phases:
a. Preclinical testing
b. Phase 1 – Safety and dosage
c. Phase 2 – Effectiveness and side effects
d. Phase 3 – Confirmation of effectiveness, monitoring of adverse reactions, and comparison with existing treatments
e. Phase 4 – Post-marketing studies to track long-term safety and effectiveness
a. Preclinical testing
b. Phase 1 – Safety and dosage
c. Phase 2 – Effectiveness and side effects
d. Phase 3 – Confirmation of effectiveness, monitoring of adverse reactions, and comparison with existing treatments
e. Phase 4 – Post-marketing studies to track long-term safety and effectiveness
What is a clinical trial?
A clinical trial is a carefully designed study in which researchers test a drug, treatment, or medical device in people to evaluate its safety, effectiveness, and potential side effects. These trials are essential for determining whether a new treatment should be approved for widespread use.
What drugs does Clearside Biomedical (CLSD) have in its pipeline
CLSD is currently developing the following drugs: Aflibercept, Cls-Ax, Cls-Ax, Anti-Vegf, Suprachoroidal Cls-Ta, Suprachoroidal Sham, Lucentis Or Avastin. These drug candidates are in various stages of clinical development as the company works toward FDA approval.