Clinical ProgressPerspective Therapeutics is progressing three Pb-212-based clinical-stage radiopharmaceutical therapies, including the VMT-α-NET RPT designed to target and deliver Pb212 to SSTR2-expressing gastroenteropancreatic neuroendocrine tumors.
Efficacy And SafetyPb-212-VMT-α-NET continues to demonstrate a safe and well tolerated profile with no records of dose-limiting toxicities, no discontinuations due to adverse events, no treatment-emergent adverse events of Grade IV or higher, and no deaths.
Regulatory ApprovalPerspective Therapeutics has reached alignment with the FDA to open Cohort 3 of its ongoing Phase I/IIa trial of Pb-212-VMT-α-NET in advanced RPT-naive NETs.