Balance Sheet And Pipeline AdvancementAn upsized follow-on public offering strengthened cash resources, enabling progression of mid-stage trials and support for advancing next-generation APJ agonist candidates toward clinical filing.
Clinical DataPhase 1 results showed strong and durable suppression of key inflammatory biomarkers in blood and cerebrospinal fluid, supporting once-daily dosing and clear target engagement for the lead NLRP3 inhibitor.
Ophthalmology ExpansionOral brain-penetrant compound also reaches the retina, with preclinical evidence of preserved retinal microvascular integrity and planned trials testing standalone and combination use in diabetic macular edema, offering a potential non-invasive alternative to eye injections.