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Amplia Therapeutics Ltd. (AU:ATX)
OTHER OTC:ATX

Amplia Therapeutics (ATX) AI Stock Analysis

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AU:ATX

Amplia Therapeutics

(OTC:ATX)

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Neutral 52 (OpenAI - 5.2)
Rating:52Neutral
Price Target:
AU$0.17
▲(22.86% Upside)
Overall score reflects weak financial performance driven by ongoing losses and negative cash flow, partially offset by a constructive technical uptrend (price above major moving averages with positive MACD). Valuation remains difficult to assess given the negative P/E and lack of dividend data.
Positive Factors
Strong Gross Margins
High gross margins indicate efficient cost management, allowing Amplia to potentially reinvest in R&D and sustain operations despite current losses.
Stable Balance Sheet
A stable balance sheet with low leverage provides financial flexibility and reduces risk, supporting long-term strategic initiatives and growth.
Revenue Growth
Positive revenue growth reflects increasing market demand and successful product development, crucial for future profitability as products mature.
Negative Factors
Ongoing Financial Losses
Persistent financial losses can strain resources and delay profitability, necessitating careful management of expenses and funding strategies.
Weak Cash Flow
Weak cash flow limits the company's ability to self-fund projects, increasing reliance on external financing, which can dilute shareholder value.
Negative Profit Margins
Negative profit margins highlight the challenge of covering high R&D costs, impacting short-term financial health and requiring strategic focus on cost control.

Amplia Therapeutics (ATX) vs. iShares MSCI Australia ETF (EWA)

Amplia Therapeutics Business Overview & Revenue Model

Company DescriptionAmplia Therapeutics (ATX) is a biotechnology company focused on developing innovative therapies for the treatment of fibrotic diseases and cancer. The company specializes in the discovery and development of small molecule drugs that target the underlying biological processes driving these conditions. Amplia's core products include its lead drug candidate, which is designed to inhibit specific pathways involved in fibrosis, thereby offering potential benefits for patients suffering from these debilitating diseases.
How the Company Makes MoneyAmplia Therapeutics generates revenue primarily through the development and commercialization of its drug candidates. The company's revenue model includes funding from grants and research partnerships, which support the clinical development of its therapies. Additionally, Amplia may enter into licensing agreements or partnerships with larger pharmaceutical companies, allowing them to share in the development costs and potential profits from successful drug candidates. Revenue can also be derived from milestone payments and royalties based on sales once products are commercialized. Furthermore, the company may attract investment through equity financing to support its ongoing research and development efforts.

Amplia Therapeutics Financial Statement Overview

Summary
Amplia Therapeutics shows strong gross margins and revenue growth, but faces ongoing losses typical for biotech firms. The balance sheet is stable with low leverage, but cash flow challenges persist.
Income Statement
45
Neutral
Amplia Therapeutics shows a mixed performance in its income statement. The company has a strong gross profit margin, consistently above 90%, indicating efficient cost management. However, the net profit margin is negative, reflecting ongoing losses, which is common in the biotechnology industry due to high R&D expenses. Revenue growth is positive, but the company has not yet achieved profitability, as evidenced by negative EBIT and EBITDA margins.
Balance Sheet
50
Neutral
The balance sheet of Amplia Therapeutics is relatively stable, with a low debt-to-equity ratio, suggesting conservative leverage. However, the return on equity is negative, indicating that the company is not generating profits from its equity base. The equity ratio is healthy, showing a strong equity position relative to total assets, which provides a buffer against financial instability.
Cash Flow
40
Negative
Amplia Therapeutics faces challenges in its cash flow statement. The company has negative operating and free cash flows, which are typical for biotech firms in the development stage. The free cash flow to net income ratio is close to 1, indicating that cash outflows are closely aligned with reported losses. Despite a significant increase in free cash flow growth, the overall cash flow position remains weak.
BreakdownTTMDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue2.38M3.78M4.45M1.19M1.98M1.53M
Gross Profit2.20M3.57M4.01M1.12M1.98M1.53M
EBITDA-10.75M-6.78M-4.48M-7.26M-3.64M-3.81M
Net Income-7.93M-6.57M-4.50M-6.24M-3.64M-2.28M
Balance Sheet
Total Assets44.54M22.94M14.85M18.68M24.48M10.88M
Cash, Cash Equivalents and Short-Term Investments29.16M10.86M3.39M9.26M14.61M1.85M
Total Debt381.42K13.89K1.59M2.27M2.10M0.00
Total Liabilities1.61M1.91M3.43M2.85M2.64M539.13K
Stockholders Equity42.93M21.02M11.42M15.84M21.85M10.34M
Cash Flow
Free Cash Flow-13.39M-6.89M-5.13M-5.31M-4.42M-2.92M
Operating Cash Flow-13.36M-6.89M-5.13M-5.29M-4.40M-2.92M
Investing Cash Flow-81.65K-2.07K-2.23K-58.42K-26.64K-5.35K
Financing Cash Flow37.99M14.32M-772.98K-84.22K17.19M3.66M

Amplia Therapeutics Technical Analysis

Technical Analysis Sentiment
Positive
Last Price0.14
Price Trends
50DMA
0.13
Positive
100DMA
0.15
Positive
200DMA
0.14
Positive
Market Momentum
MACD
<0.01
Negative
RSI
52.47
Neutral
STOCH
23.74
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For AU:ATX, the sentiment is Positive. The current price of 0.14 is below the 20-day moving average (MA) of 0.14, above the 50-day MA of 0.13, and below the 200-day MA of 0.14, indicating a bullish trend. The MACD of <0.01 indicates Negative momentum. The RSI at 52.47 is Neutral, neither overbought nor oversold. The STOCH value of 23.74 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for AU:ATX.

Amplia Therapeutics Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
52
Neutral
AU$79.53M-7.71-27.39%26.64%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
48
Neutral
AU$20.50M-9.26-1651.76%-100.00%2.86%
46
Neutral
AU$25.72M-5.27-157.93%-36.89%
44
Neutral
AU$36.73M-9.09-143.71%306.88%
40
Underperform
AU$10.57M-1.79-166.70%
37
Underperform
AU$13.77M-1.61-628.72%31.87%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
AU:ATX
Amplia Therapeutics
0.16
0.07
78.16%
AU:NOX
Noxopharm Ltd.
0.09
<0.01
6.02%
AU:NC6
Nanollose Ltd.
0.06
0.05
270.59%
AU:CMB
Regeneus Ltd.
0.46
0.05
12.20%
AU:AVE
Avecho Biotechnology Limited
0.01
0.00
0.00%
AU:1AD
AdAlta Ltd.
0.01
-0.01
-50.00%

Amplia Therapeutics Corporate Events

Amplia Showcases Promising Pancreatic Cancer Data for Narmafotinib at ASCO GI
Jan 9, 2026

Amplia Therapeutics has reported updated interim data from its Phase 2a ACCENT trial in metastatic pancreatic cancer, presented at the 2026 ASCO Gastrointestinal Cancer Symposium. The trial, which evaluates narmafotinib in combination with standard chemotherapies gemcitabine and Abraxane, shows a progression-free survival of 7.7 months versus 5.5 months for chemotherapy alone and an overall response rate of 35%, rising to 42% including unconfirmed responses, while maintaining a safety profile comparable to chemotherapy alone. Management says the ASCO GI presentation reinforces Amplia’s positioning among leading oncology developers and highlights the potential of narmafotinib to improve outcomes in advanced pancreatic cancer, complementing its broader clinical strategy that includes the newly opened AMPLICITY trial combining narmafotinib with FOLFIRINOX.

The most recent analyst rating on (AU:ATX) stock is a Hold with a A$0.17 price target. To see the full list of analyst forecasts on Amplia Therapeutics stock, see the AU:ATX Stock Forecast page.

Amplia Deepens Next & Bio Collaboration to Test Narmafotinib–kRAS Combo in Pancreatic Cancer
Dec 18, 2025

Amplia Therapeutics has entered a second phase of its preclinical research collaboration with Korean drug screening specialist Next & Bio to further investigate the effects of its FAK inhibitor narmafotinib in combination with experimental kRAS inhibitors on patient-derived pancreatic cancer cells. The extension follows encouraging initial data showing narmafotinib’s activity against kRAS-mutant pancreatic cancer models, and the partners will now explore potential synergistic effects with kRAS inhibitors, a new class of drugs under development for several solid tumours. Amplia sees this next stage as an opportunity to strengthen its scientific case for combination therapies in hard-to-treat pancreatic cancer, enhance the clinical and commercial prospects of narmafotinib and potentially broaden partnering opportunities, while Next & Bio leverages its advanced patient-derived cell platform to support the development of new treatment options in an area of high unmet medical need.

The most recent analyst rating on (AU:ATX) stock is a Hold with a A$0.12 price target. To see the full list of analyst forecasts on Amplia Therapeutics stock, see the AU:ATX Stock Forecast page.

Amplia Therapeutics Reports Positive ACCENT Trial Results for Pancreatic Cancer
Dec 11, 2025

Amplia Therapeutics announced a positive development in its ACCENT trial for metastatic pancreatic cancer, where its FAK inhibitor narmafotinib, combined with gemcitabine and nab-paclitaxel, achieved a 35% objective response rate. This result surpasses the 23% response rate of the benchmark MPACT trial, indicating a significant advancement in treatment efficacy. The data will be presented at the Life Sciences Virtual Investor Forum, highlighting Amplia’s potential impact on cancer treatment and its strategic positioning in the pharmaceutical industry.

The most recent analyst rating on (AU:ATX) stock is a Hold with a A$0.12 price target. To see the full list of analyst forecasts on Amplia Therapeutics stock, see the AU:ATX Stock Forecast page.

Amplia Therapeutics Reports Promising Trial Results for Pancreatic Cancer Drug
Nov 27, 2025

Amplia Therapeutics has announced its financial report for the half year ending September 2025, highlighting significant progress in its clinical trials. The company’s lead drug, narmafotinib, has shown promising results in the ACCENT trial for advanced pancreatic cancer, achieving a confirmed response rate of 33%, which is superior to existing treatments. A new trial, AMPLICITY, has also commenced, further exploring narmafotinib’s efficacy in combination with FOLFIRINOX.

The most recent analyst rating on (AU:ATX) stock is a Hold with a A$0.11 price target. To see the full list of analyst forecasts on Amplia Therapeutics stock, see the AU:ATX Stock Forecast page.

Amplia Therapeutics Receives FDA Support for Pancreatic Cancer Trial
Nov 20, 2025

Amplia Therapeutics has received positive feedback from the US FDA regarding its planned Phase 2b/3 trial for narmafotinib, a FAK inhibitor, in combination with gemcitabine and Abraxane for pancreatic cancer. The FDA’s support for the dose comparison design and minimal impact on timelines enhances Amplia’s confidence in proceeding with the trial, which is set to begin in late 2026, potentially strengthening its position in the oncology market.

The most recent analyst rating on (AU:ATX) stock is a Buy with a A$0.42 price target. To see the full list of analyst forecasts on Amplia Therapeutics stock, see the AU:ATX Stock Forecast page.

Amplia Therapeutics Issues New Equity Securities
Nov 10, 2025

Amplia Therapeutics Limited has announced the issuance of 480,769 unquoted equity securities in the form of Zero Exercise Price Options under an employee incentive scheme. This strategic move is likely aimed at retaining and motivating employees, potentially impacting the company’s operational efficiency and competitive positioning in the biotechnology sector.

The most recent analyst rating on (AU:ATX) stock is a Buy with a A$0.42 price target. To see the full list of analyst forecasts on Amplia Therapeutics stock, see the AU:ATX Stock Forecast page.

Amplia Therapeutics Expands U.S. Market Presence with OTCQB Listing
Oct 30, 2025

Amplia Therapeutics has commenced trading on the U.S. OTCQB Venture Market, enhancing its engagement with U.S. investors and expanding its presence in the U.S. market. This move coincides with the company’s AMPLICITY clinical trial for advanced pancreatic cancer opening at five sites in the U.S., and is part of Amplia’s broader strategy to educate investors about its FAK inhibitor program, which includes the promising drug narmafotinib.

The most recent analyst rating on (AU:ATX) stock is a Buy with a A$0.42 price target. To see the full list of analyst forecasts on Amplia Therapeutics stock, see the AU:ATX Stock Forecast page.

Amplia Therapeutics Advances Narmafotinib Trials with Promising Results
Oct 28, 2025

Amplia Therapeutics has reported significant progress in its clinical trials for narmafotinib, a FAK inhibitor, showing improved outcomes in metastatic pancreatic cancer treatment. The company has achieved key regulatory milestones, including ethics approval for a new trial combining narmafotinib with FOLFIRINOX chemotherapy and securing a patent for its drug formulation, positioning it for further commercial development and potential partnerships.

The most recent analyst rating on (AU:ATX) stock is a Buy with a A$0.42 price target. To see the full list of analyst forecasts on Amplia Therapeutics stock, see the AU:ATX Stock Forecast page.

Amplia Therapeutics Secures $3.77 Million R&D Tax Rebate to Boost Cancer Trials
Oct 28, 2025

Amplia Therapeutics has received a $3.77 million R&D tax rebate from the Australian Tax Office, which will support the progression of its clinical trials for narmafotinib, a FAK inhibitor. This funding will aid in advancing the ACCENT and AMPLICITY trials, which are exploring narmafotinib’s effectiveness in treating advanced pancreatic cancer, potentially enhancing Amplia’s position in the oncology pharmaceutical industry.

The most recent analyst rating on (AU:ATX) stock is a Buy with a A$0.42 price target. To see the full list of analyst forecasts on Amplia Therapeutics stock, see the AU:ATX Stock Forecast page.

Amplia Therapeutics Expands U.S. Presence with New Investor Campaign
Oct 17, 2025

Amplia Therapeutics is expanding its U.S. presence by increasing investor engagement and awareness through a capital markets campaign. This initiative supports its ongoing Phase 2A clinical trial for pancreatic cancer and includes plans to uplist to the OTCQB market, aiming to broaden its U.S. investor base and enhance its market positioning.

The most recent analyst rating on (AU:ATX) stock is a Buy with a A$0.42 price target. To see the full list of analyst forecasts on Amplia Therapeutics stock, see the AU:ATX Stock Forecast page.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Jan 04, 2026