Biomarker EvidenceReductions in tau species and multiple neuroinflammation markers, together with lower neurofilament light chain, suggest buntanetap may be impacting underlying neurodegeneration and support potential disease-modifying activity.
Regulatory EngagementA scheduled Type C meeting with the FDA to discuss development for Parkinson's disease dementia signals active regulatory dialogue that could clarify the approval pathway and de-risk development strategy.
Safety And Commercial ProfileOral dosing and a favorable safety profile observed so far improve patient convenience and reduce clinical development risk, enhancing the drug's commercial appeal if approved.