Strong Product Launches
Syndax reported $20 million in Revuforj net revenue and $13.6 million in Niktimvo net revenue in the first quarter of 2025, indicating successful product launches and strong market reception.
Financial Stability
The company is well-funded with $602.1 million in cash and equivalents, and anticipates reaching profitability with current revenue streams.
Pipeline Progress
The initiation of the EVOLV-2 trial, a pivotal frontline trial of revumenib, marks significant advancement in the menin inhibitor program.
NCCN Guidelines Inclusion
Revuforj has been rapidly included in NCCN guidelines, with expectations for further inclusion in clinical guidelines for mutant mNPM1 AML treatment.
FDA sNDA Submission
A Supplemental New Drug Application for Revuforj has been submitted, seeking priority review for relapse or refractory mutant mNPM1 AML.