Successful Phase 2b PROGRESS Study
The PROGRESS Phase 2b study of pillabapentin for diabetic peripheral neuropathic pain (DPNP) showed a clear separation in ADPS from baseline, with the 10-milligram dose showing meaningful improvement compared to placebo and improved tolerability.
Significant Licensing Agreement
Lexicon entered into a significant licensing agreement with Beatrice for sotagliflozin outside of the US and Europe, contributing a $25 million upfront payment.
Strong Financial Position
Ended 2024 with $238 million in cash, cash equivalents, and short-term investments, an increase from $170 million at the end of 2023.
Potential of Sotagliflozin
Research highlighted sotagliflozin's effects in reducing major adverse cardiovascular events, myocardial infarction, and stroke, showing promise as a differentiated SGLT1 and 2 inhibitor.