Increased Financial Guidance for 2025
Ionis increased its 2025 revenue guidance by more than 20% due to strong first-quarter results and recent successful licensing transactions, projecting $725 million to $750 million in revenue.
Successful Launch of TRYNGOLZA
TRYNGOLZA, the first FDA-approved treatment for familial chylomicronemia syndrome, exceeded expectations with over $6 million in net product sales in its first full quarter on the market.
Upcoming Launches and Product Pipeline
Ionis is preparing for the launch of donidalorsen for hereditary angioedema in the third quarter and expects data from two Phase III programs later this year, which could lead to significant market opportunities.
Strong Commercial Revenue Growth
Commercial product revenues grew 28% year-over-year, with robust contributions from TRYNGOLZA, SPINRAZA, and WAINUA.