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Ionis Pharmaceuticals (IONS)
NASDAQ:IONS
Earnings Data
Report Date
Apr 30, 2025TBA Not Confirmed
Period Ending
2025 (Q1)Consensus EPS Forecast
-1.1Last Year’s EPS
-0.98Same Quarter Last Year
Moderate Buy
Based on 16 Analysts Ratings
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Earnings Call Summary
Earnings Call Date:Feb 19, 2025
|% Change Since: 2.32%
|Next Earnings Date:Apr 30, 2025
Earnings Call Sentiment|Positive
The earnings call highlighted Ionis Pharmaceuticals' successful launch of Tringolza and strong financial performance, with plans for future product launches and positive market response for existing products like WAYLIVRA. However, challenges remain in patient identification and clinical outcomes, as well as a decline in R&D revenue. The positive developments and strategic plans outweigh the challenges, indicating a positive outlook.Company Guidance
In the recent conference call, Ionis Pharmaceuticals, Inc. shared their optimistic guidance for the upcoming year, highlighting several key metrics. The company reported a non-GAAP operating loss of $345 million, which was better than expected, and revenues of $705 million, surpassing their guidance by over $130 million. They anticipate earning over $600 million in revenue for 2025, driven by both existing and new product launches, including Tringolza for FCS and Donidalorsen for HAE, with Tringolza expected to address a patient population of up to 3,000 in the US. Ionis also projects a high single-digit percentage increase in operating expenses while keeping R&D expenses stable. The company aims for a non-GAAP operating loss of less than $195 million and plans to end the year with approximately $1.7 billion in cash and investments, setting the stage for substantial and sustained revenue growth and a path to positive cash flow.Successful Launch of Tringolza
Ionis Pharmaceuticals achieved a successful launch of Tringolza, the first treatment for familial chylomicronemia syndrome (FCS), with rapid prescription and patient uptake.
Future Product Launches
Ionis is on track for three additional independent launches over the next three years, with expected multibillion-dollar revenue potential.
Strong Financial Performance
Ionis reported revenue of $705 million in 2024, exceeding guidance by $130 million, with a significant improvement in non-GAAP operating loss.
WAYLIVRA Growth
WAYLIVRA product revenue increased 84% in Q4 compared to Q3, with strong demand and expanding use in the community setting.
Upcoming Data Readouts and Regulatory Actions
Ionis anticipates multiple late-stage data readouts and regulatory actions, including the potential approval of Donidalorsen for hereditary angioedema.
SPINRAZA Resilience
SPINRAZA remained a primary source of commercial revenue, generating $216 million in royalties.
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IONS Earnings History
The table shows recent earnings report dates and whether the forecast was beat or missed. See the change in forecast and EPS from the previous year.
Beat
Missed
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IONS Earnings-Related Price Changes
Report Date | Price 1 Day Before | Price 1 Day After | Percentage Change |
|---|---|---|---|
| Feb 19, 2025 | $31.95 | $31.81 | -0.44% |
| Nov 06, 2024 | $38.80 | $39.04 | +0.62% |
| Aug 01, 2024 | $49.46 | $51.32 | +3.76% |
| May 07, 2024 | $42.28 | $40.93 | -3.19% |
Earnings announcements can affect a stock’s price. This table shows the stock's price the day before and the day after recent earnings reports, including the percentage change.
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FAQ
When does Ionis Pharmaceuticals (IONS) report earnings?
Ionis Pharmaceuticals (IONS) is schdueled to report earning on Apr 30, 2025, TBA Not Confirmed.
What is Ionis Pharmaceuticals (IONS) earnings time?
Ionis Pharmaceuticals (IONS) earnings time is at Apr 30, 2025, TBA Not Confirmed.
Where can I see when companies are reporting earnings?
You can see which companies are reporting today on our designated earnings calendar.
What companies are reporting earnings today?
You can see a list of the companies which are reporting today on TipRanks earnings calendar.
What is IONS EPS forecast?
IONS EPS forecast for the fiscal quarter 2025 (Q1) is -1.1.
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