Top- and Bottom-Line Results in Line with Guidance
Reported FY2025 revenue of $4,020,000,000 with non-GAAP EPS nearly flat at $10.28 (vs $10.32 in 2024); management delivered results at the upper end of their November revenue and non-GAAP EPS ranges.
DSA Net Book-to-Bill and Backlog Improvement
DSA net book-to-bill improved to 1.12x in Q4 2025 with net bookings of $665,000,000; backlog modestly rose to $1,860,000,000 from $1,800,000,000 at Q3-end, signaling improving demand momentum into 2026.
Strategic M&A to Strengthen Supply Chain and NAMS
Acquisition of KF Cambodia (closed) to secure NHP supply and reduce sourcing costs; planned acquisition of PathoQuest (expected close soon) to expand NAMS/biologics testing capabilities (PathoQuest expected to provide a small revenue benefit in 2026).
Guidance Calls for EPS Growth and Margin Expansion in 2026
2026 non-GAAP EPS guidance $10.70–$11.20 (≈ +4% to +9%); organic revenue guidance of down ~1% to at least flat (reported revenue at least flat to +1.5%); consolidated operating margin expected to improve by 20–50 bps from 19.8% in 2025.
KF Acquisition Financial Benefits
Management expects the KF Cambodia acquisition to add ~ $0.25 to 2026 EPS (embedded in guidance) and to improve consolidated operating margin by >50 bps (and DSA margin by >100 bps), with further accretion expected into 2027 (management referenced ~ $0.60 accretion by 2027).
Manufacturing and Microbial Strength
Manufacturing Solutions operating margin improved to 32.1% in Q4 (+340 bps) and to 28.8% for the full year (+140 bps); Microbial Solutions reported strong growth across EndoSafe, Celsis and Accugenix platforms; biologics testing returned to modest growth in Q4 after client-specific headwinds.
Cost Savings and Capital Discipline
Company expects at least $100,000,000 incremental annual cost savings above 2025 levels in 2026 and continues to target cumulative annualized savings of >$300,000,000 from actions implemented over the last three years; net interest expense expected to decline to $95M–$100M (vs $102.1M in 2025) and leverage remains comfortable (~2.0x net).
Balance Sheet & Cash Flow Framework
Debt at ~$2.1B (≈70% fixed); management expects to fund KF/PathoQuest (~$500M+) and focus on debt repayment and maintaining dry powder; 2026 capex targeted at ~$200M (~5% of revenue).