Record-Breaking Revenue and Growth
Argenx reported total product net sales of $1.13 billion in Q3 2025, surpassing $1 billion in VYVGART sales in a single quarter for the first time. This represents a 19% growth from the previous quarter and a 96% growth year-over-year.
Successful PFS Launch
The prefilled syringe (PFS) is driving increased demand, with over 50% of new patients starting on PFS. This has expanded the prescriber base, with over 260 new prescribers writing their first VYVGART prescriptions.
Strong Performance Across Geographies
Product net sales breakdown: $964 million in the U.S., $60 million in Japan, $94 million in other global markets, and $9 million for product supply to Zai Lab in China.
Pipeline Progress
Argenx now has 3 first-in-class molecules in Phase III development and expects to begin Phase III studies for Graves' disease early next year.
Positive Data in MG
VYVGART showed up to 60% of patients reaching minimum symptom expression with 83% maintaining it for at least 8 weeks. Additionally, over 55% of patients reduced steroid use to below 5 mg/day after 18 months.