Strong Financial Position
Amylyx Pharmaceuticals ended the third quarter with a cash position of $344 million, up from $181 million at the end of the second quarter, due to the completion of a public offering in September which provided approximately $191 million of net proceeds.
Advancement in ALS Program
The company fully enrolled Cohort 1 in the Phase I LUMINA trial for AMX0114 and plans to share safety data at an upcoming ALS and MMD symposium. Biomarker data is anticipated to be available in the coming months.
Decrease in Operating Expenses
Total operating expenses for the quarter were $36 million, down 53% from the same period in 2024, primarily due to decreased onetime expenses related to the acquisition of avexitide.
FDA Breakthrough Therapy Designation for Avexitide
Avexitide, the company's investigational inhibitor of GLP-1 receptor activity, continues to progress with high participant interest in the LUCIDITY trial, and has FDA breakthrough therapy designation.