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PharmAla Biotech Holdings, Inc. (TSE:MDMA)
:MDMA
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PharmAla Biotech Holdings, Inc. (MDMA) AI Stock Analysis

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TSE:MDMA

PharmAla Biotech Holdings, Inc.

(MDMA)

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Neutral 50 (OpenAI - 5.2)
Rating:50Neutral
Price Target:
C$0.16
▲(40.91% Upside)
Action:ReiteratedDate:04/24/26
The score is held back primarily by weak financial performance (negative gross profit, ongoing losses, and continued cash burn), partially offset by a debt-free balance sheet. Technicals are supportive with price above major moving averages and positive MACD, but overbought RSI reduces confidence. Valuation remains pressured due to negative earnings and no dividend support.
Positive Factors
Debt-free balance sheet
Zero reported debt gives the company durable financial flexibility to fund clinical-stage activities and capex without near-term interest burden. Over 2-6 months this reduces refinancing risk and supports continuing R&D and supply investments while revenues scale.
Negative Factors
Negative gross profit
Reversion to negative gross profit signals deteriorating unit economics and weak pricing or rising direct costs. If sustained, this undermines the ability to scale commercial supply profitably and requires cost restructuring or higher pricing to restore sustainable margins.
Read all positive and negative factors
Positive Factors
Negative Factors
Debt-free balance sheet
Zero reported debt gives the company durable financial flexibility to fund clinical-stage activities and capex without near-term interest burden. Over 2-6 months this reduces refinancing risk and supports continuing R&D and supply investments while revenues scale.
Read all positive factors

PharmAla Biotech Holdings, Inc. (MDMA) vs. iShares MSCI Canada ETF (EWC)

PharmAla Biotech Holdings, Inc. Business Overview & Revenue Model

Company Description
Pharmala Biotech Holdings Inc., doing business as PharmAla, focuses on the developing, manufacturing, and commercializing of substituted methylenedioxy-phenethylamines (MDXX) active pharmaceutical ingredients. It also provides MDXX class compounds...
How the Company Makes Money
null...

PharmAla Biotech Holdings, Inc. Financial Statement Overview

Summary
Despite TTM revenue growth (+17.88%), profitability and cash quality are weak: gross profit is negative, operating and net losses remain large, and both operating cash flow and free cash flow are negative with ongoing cash burn. The balance sheet helps (zero debt), but persistent losses keep overall financial strength low.
Income Statement
18
Very Negative
Balance Sheet
62
Positive
Cash Flow
28
Negative
BreakdownTTMNov 2025Nov 2024Nov 2023Nov 2022Aug 2021
Income Statement
Total Revenue889.57K605.50K1.04M532.00K78.07K0.00
Gross Profit-523.49K-845.17K887.44K454.10K75.78K-303.00
EBITDA-1.55M-2.07M-573.36K-710.18K-973.45K-2.51M
Net Income-1.63M-2.18M-823.60K-779.81K-985.58K-2.51M
Balance Sheet
Total Assets3.13M3.42M2.90M2.41M2.33M2.79M
Cash, Cash Equivalents and Short-Term Investments564.71K960.66K419.38K195.04K852.14K2.47M
Total Debt0.000.000.00253.54K0.000.00
Total Liabilities973.42K961.73K916.88K1.03M423.78K138.48K
Stockholders Equity2.16M2.46M1.98M1.38M1.91M2.66M
Cash Flow
Free Cash Flow-928.74K-1.05M-547.78K-846.39K-1.62M-435.76K
Operating Cash Flow-918.37K-1.04M-321.36K-339.66K-625.37K-173.57K
Investing Cash Flow769.26K-935.27K-226.42K-506.74K-994.87K629.22K
Financing Cash Flow-3.05K1.60M772.12K189.29K0.002.02M

PharmAla Biotech Holdings, Inc. Technical Analysis

Technical Analysis Sentiment
Negative
Last Price0.11
Price Trends
50DMA
0.10
Negative
100DMA
0.10
Negative
200DMA
0.11
Negative
Market Momentum
MACD
>-0.01
Positive
RSI
46.41
Neutral
STOCH
65.00
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For TSE:MDMA, the sentiment is Negative. The current price of 0.11 is above the 20-day moving average (MA) of 0.10, above the 50-day MA of 0.10, and above the 200-day MA of 0.11, indicating a bearish trend. The MACD of >-0.01 indicates Positive momentum. The RSI at 46.41 is Neutral, neither overbought nor oversold. The STOCH value of 65.00 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for TSE:MDMA.

PharmAla Biotech Holdings, Inc. Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
50
Neutral
C$15.79M-7.66-78.88%125.00%25.37%
48
Neutral
C$6.00M-0.15123.88%77.21%
46
Neutral
C$9.10M-10.53-112.32%1.20%
42
Neutral
C$14.67M-5.2521.59%-120.00%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
TSE:MDMA
PharmAla Biotech Holdings, Inc.
0.15
0.00
0.00%
TSE:CSCI
COSCIENS Biopharma
2.70
-1.74
-39.19%
TSE:APS
Aptose Biosciences
2.35
-0.79
-25.16%
TSE:SBM.H
Sirona Biochem
0.06
0.00
0.00%
TSE:PREV
PreveCeutical Medical
0.03
>-0.01
-16.67%
TSE:PHRM
PharmaTher Holdings Ltd
0.10
-0.10
-51.22%

PharmAla Biotech Holdings, Inc. Corporate Events

Business Operations and StrategyProduct-Related Announcements
Cortexa Deepens Lead in Australia’s MDMA Market With New GMP Supply and Expanded Access
Positive
Mar 23, 2026
Cortexa, a 50/50 joint venture between PharmAla Biotech and Vitura Health, has reinforced its leadership in Australia’s emerging psychedelic medicines market by commercializing the country’s first large‑scale GMP batch of MDMA ca...
Business Operations and Strategy
PharmAla Expands MDMA Trial Footprint With Nautilus Sanctuary Data Deal
Positive
Mar 3, 2026
PharmAla Biotech has signed a Supply Data Agreement with Nautilus Sanctuary in New York to provide its LaNeo MDMA for a Phase 2 open-label clinical trial using MDMA-assisted therapy to treat post-traumatic stress and adjustment disorders in front...
Business Operations and Strategy
PharmAla Donates MDMA for Fibromyalgia Trial in Major U.S. Research Collaboration
Positive
Feb 26, 2026
PharmAla Biotech has signed a drug donation agreement with Spaulding Rehabilitation, part of the Mass General Brigham system, to supply its LaNeo MDMA at no cost for a clinical trial investigating MDMA-assisted therapy in fibromyalgia patients. In...
Business Operations and StrategyProduct-Related Announcements
PharmAla Strikes Amsterdam UMC Supply Deal to Advance Commercial-Grade MDMA Packaging
Positive
Feb 23, 2026
PharmAla Biotech Holdings has signed a binding supply agreement with Amsterdam University Medical Center in the Netherlands to provide LaNeo 40 mg MDMA capsules for a proposed clinical trial. The product will be repackaged into a new single-capsul...
Business Operations and StrategyExecutive/Board Changes
PharmAla Biotech Reshapes Board With Addition of Veteran Financial Executive
Positive
Feb 10, 2026
PharmAla Biotech Holdings Inc., a specialist in MDMA and MDXX-class psychedelic molecules, develops and manufactures clinical-grade compounds for research and patient treatments while advancing proprietary candidates such as its lead asset ALA-002...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Apr 24, 2026